SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uif'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 3uif SULFONATE ABC
TRANSPORTER,
PERIPLASMIC
SULFONATE-BINDING
PROTEIN SSUA
(Methylobacillus
flagellatus) 		5 / 12 VAL A 251
LEU A 248
VAL A 244
VAL A 114
GLY A 118
 None
None
None
None
GOL  A 503 ( 3.8A)
 0.97A 2cbrA-3uifA:
undetectable		 2cbrA-3uifA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_2
(PROTEASE)		 3uif SULFONATE ABC
TRANSPORTER,
PERIPLASMIC
SULFONATE-BINDING
PROTEIN SSUA
(Methylobacillus
flagellatus) 		5 / 11 ALA A  73
ILE A  91
GLY A  94
ILE A  95
VAL A  78
 None
 1.05A 2nnpB-3uifA:
undetectable		 2nnpB-3uifA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_2
(PROTEASE)		 3uif SULFONATE ABC
TRANSPORTER,
PERIPLASMIC
SULFONATE-BINDING
PROTEIN SSUA
(Methylobacillus
flagellatus) 		5 / 11 ALA A  73
ILE A  91
ILE A  95
PRO A 101
VAL A  78
 None
 0.81A 2nnpB-3uifA:
undetectable		 2nnpB-3uifA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_B_BEZB194_0
(PUTATIVE KINASE)		 3uif SULFONATE ABC
TRANSPORTER,
PERIPLASMIC
SULFONATE-BINDING
PROTEIN SSUA
(Methylobacillus
flagellatus) 		4 / 5 PRO A 273
ILE A 200
ARG A 279
ASP A 203
 SO4  A 502 (-4.3A)
None
None
None
 1.22A 2rhmB-3uifA:
undetectable		 2rhmB-3uifA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_D_BEZD194_0
(PUTATIVE KINASE)		 3uif SULFONATE ABC
TRANSPORTER,
PERIPLASMIC
SULFONATE-BINDING
PROTEIN SSUA
(Methylobacillus
flagellatus) 		4 / 5 PRO A 273
ILE A 200
ARG A 279
ASP A 203
 SO4  A 502 (-4.3A)
None
None
None
 1.24A 2rhmD-3uifA:
undetectable		 2rhmD-3uifA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3uif SULFONATE ABC
TRANSPORTER,
PERIPLASMIC
SULFONATE-BINDING
PROTEIN SSUA
(Methylobacillus
flagellatus) 		4 / 4 LEU A 184
ALA A 145
VAL A 175
PRO A 177
 None
None
None
SO4  A 501 (-4.1A)
 1.20A 3gv1B-3uifA:
undetectable		 3gv1B-3uifA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 3uif SULFONATE ABC
TRANSPORTER,
PERIPLASMIC
SULFONATE-BINDING
PROTEIN SSUA
(Methylobacillus
flagellatus) 		4 / 8 LEU A 201
GLY A 207
GLU A 202
ALA A 133
 None
 0.74A 4rjdA-3uifA:
undetectable
4rjdB-3uifA:
undetectable		 4rjdA-3uifA:
11.25
4rjdB-3uifA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3uif SULFONATE ABC
TRANSPORTER,
PERIPLASMIC
SULFONATE-BINDING
PROTEIN SSUA
(Methylobacillus
flagellatus) 		4 / 5 VAL A 298
ILE A  91
PRO A 116
THR A 240
 None
 1.31A 4ze1A-3uifA:
undetectable		 4ze1A-3uifA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YK2_A_ERYA501_0
(PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER)		 3uif SULFONATE ABC
TRANSPORTER,
PERIPLASMIC
SULFONATE-BINDING
PROTEIN SSUA
(Methylobacillus
flagellatus) 		5 / 11 GLU A  69
GLY A  94
ALA A  33
ILE A 243
VAL A 226
 None
 1.16A 5yk2A-3uifA:
0.9		 5yk2A-3uifA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB602_0
(AMINE OXIDASE LKCE)		 3uif SULFONATE ABC
TRANSPORTER,
PERIPLASMIC
SULFONATE-BINDING
PROTEIN SSUA
(Methylobacillus
flagellatus) 		4 / 6 ASN A 269
TYR A 272
VAL A  44
VAL A  39
 None
 1.42A 6f32B-3uifA:
undetectable		 6f32B-3uifA:
22.35