SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uiw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CTR_A_TFPA153_1
(CALMODULIN)		 3uiw GLUTAREDOXIN 2
(Danio
rerio) 		5 / 9 ILE A  86
LEU A 106
GLU A  49
ALA A  52
VAL A  29
 None
 1.22A 1ctrA-3uiwA:
undetectable		 1ctrA-3uiwA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3uiw GLUTAREDOXIN 2
(Danio
rerio) 		3 / 3 GLN A  89
ILE A  50
HIS A 101
 None
 0.68A 1fm9A-3uiwA:
undetectable		 1fm9A-3uiwA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3uiw GLUTAREDOXIN 2
(Danio
rerio) 		3 / 3 GLN A  89
ILE A  50
HIS A 101
 None
 0.66A 1k74A-3uiwA:
undetectable		 1k74A-3uiwA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_D_NCAD510_0
(NAD-DEPENDENT
DEACETYLASE 2)		 3uiw GLUTAREDOXIN 2
(Danio
rerio) 		4 / 5 ALA A  43
PHE A  47
ILE A  91
ASP A  96
 None
 1.16A 1yc2D-3uiwA:
undetectable		 1yc2D-3uiwA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3uiw GLUTAREDOXIN 2
(Danio
rerio) 		5 / 12 VAL A  57
ILE A  23
ASN A  27
SER A  26
PHE A  19
 None
 1.44A 2vdyB-3uiwA:
undetectable		 2vdyB-3uiwA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 3uiw GLUTAREDOXIN 2
(Danio
rerio) 		5 / 11 GLN A  89
PHE A  85
GLY A  88
ALA A  73
GLY A  77
 None
 1.34A 4a6nA-3uiwA:
undetectable		 4a6nA-3uiwA:
20.30