SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uiz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 3uiz CHIMERA PROTEIN OF
SEFD AND SEFA
(Salmonella
enterica) 		5 / 12 ALA A 114
ILE A 112
ILE A  69
GLY A  82
ILE A  81
 None
 0.90A 2hs1B-3uizA:
undetectable		 2hs1B-3uizA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_1
(PROTEASE)		 3uiz CHIMERA PROTEIN OF
SEFD AND SEFA
(Salmonella
enterica) 		5 / 12 ALA A 114
ILE A 112
ILE A  69
GLY A  82
ILE A  81
 None
 1.01A 2o4nA-3uizA:
undetectable		 2o4nA-3uizA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 3uiz CHIMERA PROTEIN OF
SEFD AND SEFA
(Salmonella
enterica) 		5 / 9 ASP A 106
ILE A 138
ILE A  95
ILE A  18
ILE A 103
 None
 0.92A 3s43A-3uizA:
undetectable		 3s43A-3uizA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 3uiz CHIMERA PROTEIN OF
SEFD AND SEFA
(Salmonella
enterica) 		5 / 12 ALA A 114
ILE A 112
ILE A  69
GLY A  82
ILE A  81
 None
 0.91A 4q1xB-3uizA:
undetectable		 4q1xB-3uizA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)		 3uiz CHIMERA PROTEIN OF
SEFD AND SEFA
(Salmonella
enterica) 		5 / 12 ALA A 114
ILE A 112
ILE A  69
GLY A  82
ILE A  81
 None
 0.95A 4q1yB-3uizA:
undetectable		 4q1yB-3uizA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3uiz CHIMERA PROTEIN OF
SEFD AND SEFA
(Salmonella
enterica) 		5 / 10 ILE A 138
ILE A 103
PHE A  97
VAL A 136
ILE A  67
 None
 1.26A 5lg3G-3uizA:
undetectable		 5lg3G-3uizA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3uiz CHIMERA PROTEIN OF
SEFD AND SEFA
(Salmonella
enterica) 		5 / 10 ILE A 138
ILE A 103
PHE A  97
VAL A 136
ILE A  67
 None
 1.24A 5lg3H-3uizA:
undetectable		 5lg3H-3uizA:
18.15