SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uj1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 3uj1 THIOREDOXIN
DOMAIN-CONTAINING
PROTEIN 5
(Homo
sapiens) 		3 / 3 PHE A 332
ARG A 385
ASN A 386
 None
 0.91A 1xzxX-3uj1A:
undetectable		 1xzxX-3uj1A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 3uj1 THIOREDOXIN
DOMAIN-CONTAINING
PROTEIN 5
(Homo
sapiens) 		4 / 7 PHE A 332
VAL A 379
ILE A 343
SER A 389
 None
 0.97A 3pglA-3uj1A:
undetectable		 3pglA-3uj1A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 3uj1 THIOREDOXIN
DOMAIN-CONTAINING
PROTEIN 5
(Homo
sapiens) 		4 / 7 ILE A 343
PHE A 402
VAL A 379
ILE A 387
 None
 0.98A 4zzbC-3uj1A:
undetectable
4zzbD-3uj1A:
undetectable		 4zzbC-3uj1A:
16.50
4zzbD-3uj1A:
16.50