SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uj2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		3 / 3 ALA A 268
VAL A 273
TRP A 276
 None
 0.79A 1c4dA-3uj2A:
undetectable
1c4dB-3uj2A:
undetectable		 1c4dA-3uj2A:
3.87
1c4dB-3uj2A:
3.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		3 / 3 ALA A 268
VAL A 273
TRP A 276
 None
 0.94A 1c4dC-3uj2A:
undetectable
1c4dD-3uj2A:
undetectable		 1c4dC-3uj2A:
3.87
1c4dD-3uj2A:
3.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		3 / 3 TRP A 276
ALA A 268
VAL A 273
 None
 0.93A 1c4dC-3uj2A:
undetectable
1c4dD-3uj2A:
undetectable		 1c4dC-3uj2A:
3.87
1c4dD-3uj2A:
3.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		4 / 5 ARG A  54
LYS A  68
ALA A  69
GLY A 109
 None
 1.11A 1e7cA-3uj2A:
2.1		 1e7cA-3uj2A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		4 / 7 TYR A 405
ILE A 169
PRO A 171
ALA A 180
 None
 1.02A 1oniD-3uj2A:
undetectable
1oniE-3uj2A:
undetectable		 1oniD-3uj2A:
15.10
1oniE-3uj2A:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		3 / 3 SER A 278
ASP A 217
CYH A 263
 None
 1.00A 2br4E-3uj2A:
undetectable		 2br4E-3uj2A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		4 / 7 ARG A  12
ALA A 115
ASN A 111
ALA A  39
 None
 1.05A 2ejfA-3uj2A:
undetectable		 2ejfA-3uj2A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		5 / 11 ALA A 220
ILE A 221
VAL A 164
LEU A 272
ILE A 288
 None
 1.21A 2h42A-3uj2A:
undetectable		 2h42A-3uj2A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_B_VIAB902_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		6 / 12 ALA A 220
ILE A 221
VAL A 164
ALA A 245
LEU A 272
ILE A 288
 None
 1.18A 2h42B-3uj2A:
undetectable		 2h42B-3uj2A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		4 / 6 ARG A 134
SER A 418
LEU A 415
GLY A 416
 None
 0.99A 2j2pA-3uj2A:
undetectable
2j2pC-3uj2A:
undetectable		 2j2pA-3uj2A:
18.97
2j2pC-3uj2A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		4 / 6 ARG A 134
SER A 418
LEU A 415
GLY A 416
 None
 0.98A 2j2pD-3uj2A:
undetectable
2j2pF-3uj2A:
undetectable		 2j2pD-3uj2A:
18.97
2j2pF-3uj2A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3K_A_SAMA1254_0
(ESSENTIAL FOR
MITOTIC GROWTH 1)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		5 / 10 VAL A  33
GLY A  32
SER A  87
LEU A   4
ALA A 127
 None
 0.85A 2v3kA-3uj2A:
undetectable		 2v3kA-3uj2A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGQ_A_PCFA1275_0
(WNT INHIBITORY
FACTOR 1)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		5 / 12 LEU A 132
ILE A 411
LEU A 144
PRO A 147
VAL A 348
 None
 1.05A 2ygqA-3uj2A:
undetectable		 2ygqA-3uj2A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		3 / 3 GLY A  37
PRO A  40
LEU A 114
 None
 0.59A 3hcpB-3uj2A:
undetectable		 3hcpB-3uj2A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		5 / 9 LEU A 382
THR A 378
GLY A  37
ALA A 119
ILE A  89
 None
 1.46A 3jusB-3uj2A:
undetectable		 3jusB-3uj2A:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		5 / 12 LEU A  81
ALA A  86
ILE A 118
VAL A   9
ILE A   6
 None
 1.04A 3nu3A-3uj2A:
undetectable		 3nu3A-3uj2A:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		5 / 12 ARG A  60
SER A 106
GLU A  13
ALA A  69
ASN A  72
 None
 1.25A 3sxjA-3uj2A:
undetectable		 3sxjA-3uj2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		5 / 12 ARG A  60
SER A 106
GLU A  13
ALA A  69
ASN A  72
 None
 1.26A 3sxjB-3uj2A:
undetectable		 3sxjB-3uj2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		4 / 4 ASP A 293
ASP A 296
GLY A 291
THR A 304
 None
 1.16A 3tl9B-3uj2A:
undetectable		 3tl9B-3uj2A:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		5 / 9 ALA A 246
GLY A 291
LEU A 260
ASP A 293
LEU A 292
 MG  A 431 ( 4.8A)
None
None
None
None
 1.12A 3wdmC-3uj2A:
undetectable		 3wdmC-3uj2A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		5 / 11 ASP A 104
VAL A 113
ALA A 112
GLY A 101
SER A 106
 None
 1.23A 4mm9A-3uj2A:
undetectable		 4mm9A-3uj2A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		5 / 12 MET A 170
LYS A 310
ILE A 285
ILE A 288
THR A 364
 None
 1.04A 4pstA-3uj2A:
undetectable		 4pstA-3uj2A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		4 / 8 GLY A 394
GLU A 207
GLU A 289
ALA A 242
 None
None
MG  A 431 (-3.3A)
None
 0.81A 4rjdA-3uj2A:
undetectable
4rjdB-3uj2A:
undetectable		 4rjdA-3uj2A:
11.56
4rjdB-3uj2A:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		3 / 3 MET A 148
GLN A 183
TYR A 233
 None
 1.10A 4udcA-3uj2A:
undetectable		 4udcA-3uj2A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		4 / 8 ALA A 385
ASN A 142
HIS A 359
THR A 388
 None
 1.11A 5db5A-3uj2A:
undetectable
5db5B-3uj2A:
undetectable		 5db5A-3uj2A:
23.58
5db5B-3uj2A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		4 / 7 TYR A 133
ALA A 125
GLU A 414
GLY A 129
 None
 0.83A 5e26A-3uj2A:
undetectable
5e26B-3uj2A:
undetectable		 5e26A-3uj2A:
22.54
5e26B-3uj2A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		4 / 7 GLU A 414
GLY A 129
TYR A 133
ALA A 125
 None
 0.81A 5e26C-3uj2A:
undetectable
5e26D-3uj2A:
undetectable		 5e26C-3uj2A:
22.54
5e26D-3uj2A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		4 / 8 ASN A 160
PHE A 167
HIS A 157
THR A 202
 None
 1.35A 5hqaA-3uj2A:
3.5		 5hqaA-3uj2A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		5 / 9 ALA A 125
ALA A 121
GLY A 138
ALA A 385
ASP A 381
 None
 1.11A 5l5zK-3uj2A:
undetectable
5l5zL-3uj2A:
undetectable		 5l5zK-3uj2A:
18.48
5l5zL-3uj2A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		5 / 9 ALA A 125
ALA A 121
GLY A 138
ALA A 385
ASP A 381
 None
 1.11A 5l5zY-3uj2A:
undetectable
5l5zZ-3uj2A:
undetectable		 5l5zY-3uj2A:
18.48
5l5zZ-3uj2A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		4 / 7 ARG A 282
LEU A 279
ILE A 224
LEU A 241
 None
 1.06A 5te8A-3uj2A:
undetectable		 5te8A-3uj2A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		4 / 8 GLN A 301
ARG A 305
GLU A 270
SER A 269
 None
 0.94A 6c06C-3uj2A:
undetectable		 6c06C-3uj2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 3uj2 ENOLASE 1
(Anaerostipes
caccae) 		4 / 7 GLY A 362
TYR A 363
GLU A 332
GLY A 329
 None
 0.88A 6n7fA-3uj2A:
undetectable		 6n7fA-3uj2A:
11.09