SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ujg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		3 / 3 GLY A 162
GLU A  65
ASN A  31
 None
 0.53A 1zq9A-3ujgA:
undetectable		 1zq9A-3ujgA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		4 / 7 TYR A 215
GLY A 178
THR A 179
TYR A 182
 None
 1.06A 2g70B-3ujgA:
undetectable		 2g70B-3ujgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		5 / 12 ILE A 257
VAL A 128
LEU A 143
PHE A 121
MET A 210
 None
 1.27A 2jj8C-3ujgA:
undetectable		 2jj8C-3ujgA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		4 / 5 VAL A 236
VAL A 205
GLY A 204
TRP A 201
 None
 1.08A 2p2fA-3ujgA:
undetectable		 2p2fA-3ujgA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		4 / 7 SER A 129
CYH A 131
GLN A 123
ILE A  77
 None
 1.06A 2xz5A-3ujgA:
undetectable
2xz5B-3ujgA:
undetectable		 2xz5A-3ujgA:
18.90
2xz5B-3ujgA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		3 / 3 SER A  29
GLU A  65
ASP A  59
 None
 0.69A 2zulA-3ujgA:
undetectable		 2zulA-3ujgA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		3 / 3 SER A  29
GLU A  65
ASP A  59
 None
 0.68A 3dmhA-3ujgA:
undetectable		 3dmhA-3ujgA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_1
(PROTEASE)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		5 / 9 LEU A 156
GLY A 100
ALA A  97
VAL A  78
GLY A  30
 None
 1.01A 3ektA-3ujgA:
undetectable		 3ektA-3ujgA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B2000_1
(P38A)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		5 / 10 ILE A 183
ILE A 257
ILE A 266
TRP A 201
VAL A 187
 None
 1.44A 3ohtA-3ujgA:
17.5
3ohtB-3ujgA:
6.1		 3ohtA-3ujgA:
25.71
3ohtB-3ujgA:
25.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		3 / 3 TYR A 182
THR A 206
GLU A 218
 None
 0.71A 4df3A-3ujgA:
undetectable		 4df3A-3ujgA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		3 / 3 TYR A 182
THR A 206
GLU A 218
 None
 0.73A 4df3B-3ujgA:
undetectable		 4df3B-3ujgA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_2
(ASPARTYL PROTEASE)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		5 / 9 LEU A 156
GLY A 100
ALA A  97
VAL A  78
GLY A  30
 None
 1.07A 4dqcB-3ujgA:
undetectable		 4dqcB-3ujgA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		5 / 12 LEU A 141
VAL A 128
ALA A 184
PHE A 121
THR A 206
 None
 1.42A 4iaqA-3ujgA:
2.9		 4iaqA-3ujgA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		5 / 12 LEU A 141
VAL A 128
ALA A 184
PHE A 121
THR A 206
 None
 1.40A 4iarA-3ujgA:
3.8		 4iarA-3ujgA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		3 / 3 GLN A 135
SER A 166
ASP A 140
 None
 0.92A 4qwpA-3ujgA:
undetectable
4qwpB-3ujgA:
undetectable		 4qwpA-3ujgA:
21.51
4qwpB-3ujgA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		5 / 9 ILE A 246
GLU A 114
LEU A 124
LEU A 253
ILE A 271
 None
 1.10A 4r38C-3ujgA:
undetectable		 4r38C-3ujgA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		5 / 12 LEU A 207
ILE A 271
GLU A 114
LEU A 211
SER A 247
 None
 1.27A 4r88A-3ujgA:
undetectable		 4r88A-3ujgA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		5 / 12 LEU A 207
ILE A 271
GLU A 114
LEU A 211
SER A 247
 None
 1.23A 4r88B-3ujgA:
undetectable		 4r88B-3ujgA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		5 / 12 LEU A 207
ILE A 271
GLU A 114
LEU A 211
SER A 247
 None
 1.25A 4r88C-3ujgA:
undetectable		 4r88C-3ujgA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		5 / 12 LEU A 207
ILE A 271
GLU A 114
LEU A 211
SER A 247
 None
 1.26A 4r88D-3ujgA:
undetectable		 4r88D-3ujgA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		5 / 12 LEU A 207
ILE A 271
GLU A 114
LEU A 211
SER A 247
 None
 1.24A 4r88E-3ujgA:
undetectable		 4r88E-3ujgA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		5 / 12 LEU A 207
ILE A 271
GLU A 114
LEU A 211
SER A 247
 None
 1.25A 4r88F-3ujgA:
undetectable		 4r88F-3ujgA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		3 / 3 GLU A  60
ILE A 305
ALA A 313
 None
 0.65A 4wnwB-3ujgA:
undetectable		 4wnwB-3ujgA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_2
(ESTROGEN RECEPTOR)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		4 / 5 LEU A 156
GLU A 101
LEU A 141
HIS A  74
 None
 1.03A 4xi3B-3ujgA:
undetectable		 4xi3B-3ujgA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_C_Z80C401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		5 / 9 ILE A  52
THR A 316
GLU A  60
ASP A  59
ILE A 312
 None
 1.43A 5lg3C-3ujgA:
2.1		 5lg3C-3ujgA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSA_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		4 / 4 TYR A 182
SER A 202
GLU A 186
ASP A 199
 None
 1.48A 5lsaA-3ujgA:
undetectable		 5lsaA-3ujgA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		5 / 12 LEU A 147
GLY A  99
SER A  98
LEU A  37
LEU A  46
 None
 1.08A 5nwvA-3ujgA:
undetectable		 5nwvA-3ujgA:
6.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE0_A_XINA401_1
(AP2-ASSOCIATED
PROTEIN KINASE 1)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		5 / 12 LEU A  37
ALA A  48
VAL A  78
GLY A 100
LEU A 147
 None
 0.38A 5te0A-3ujgA:
20.2		 5te0A-3ujgA:
27.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E
(Arabidopsis
thaliana) 		3 / 3 ARG A 155
HIS A  74
ARG A  79
 None
 1.15A 6dwdD-3ujgA:
undetectable		 6dwdD-3ujgA:
20.97