SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uji'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3uji FAB REGION OF THE
HEAVY CHAIN OF
ANTI-HIV-1 V3
MONOCLONAL ANTIBODY
2558
(Homo
sapiens) 		4 / 5 TYR H  91
MET H  89
THR H 107
LEU H 108
 None
 1.43A 2eimW-3ujiH:
undetectable		 2eimW-3ujiH:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 3uji FAB REGION OF THE
HEAVY CHAIN OF
ANTI-HIV-1 V3
MONOCLONAL ANTIBODY
2558
(Homo
sapiens) 		4 / 5 TYR H  91
MET H  89
THR H 107
LEU H 108
 None
 1.43A 3ag2J-3ujiH:
undetectable		 3ag2J-3ujiH:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 3uji FAB REGION OF THE
HEAVY CHAIN OF
ANTI-HIV-1 V3
MONOCLONAL ANTIBODY
2558
(Homo
sapiens) 		4 / 5 TYR H  91
MET H  89
THR H 107
LEU H 108
 None
 1.43A 3ag4J-3ujiH:
undetectable		 3ag4J-3ujiH:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 3uji FAB REGION OF THE
HEAVY CHAIN OF
ANTI-HIV-1 V3
MONOCLONAL ANTIBODY
2558
(Homo
sapiens) 		5 / 11 GLN H  39
PRO H  41
TYR H  59
ILE H  67
ILE H  20
 None
 1.32A 3ganA-3ujiH:
undetectable		 3ganA-3ujiH:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 3uji FAB REGION OF THE
HEAVY CHAIN OF
ANTI-HIV-1 V3
MONOCLONAL ANTIBODY
2558
(Homo
sapiens) 		5 / 10 VAL H 163
VAL H 182
SER H 180
ASN H 197
ASN H 155
 None
 1.46A 4ldoA-3ujiH:
undetectable		 4ldoA-3ujiH:
18.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 3uji FAB REGION OF THE
HEAVY CHAIN OF
ANTI-HIV-1 V3
MONOCLONAL ANTIBODY
2558
(Homo
sapiens) 		4 / 5 VAL H   2
TYR H  27
ARG H  94
TYR H 102
 None
 0.28A 4m7kH-3ujiH:
22.3		 4m7kH-3ujiH:
74.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 3uji FAB REGION OF THE
HEAVY CHAIN OF
ANTI-HIV-1 V3
MONOCLONAL ANTIBODY
2558
(Homo
sapiens) 		3 / 3 ASN H  31
ASP H 100
GLY H  99
 None
 0.64A 5fctB-3ujiH:
undetectable		 5fctB-3ujiH:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3uji FAB REGION OF THE
HEAVY CHAIN OF
ANTI-HIV-1 V3
MONOCLONAL ANTIBODY
2558
(Homo
sapiens) 		4 / 5 TYR H  91
MET H  89
THR H 107
LEU H 108
 None
 1.43A 5z86J-3ujiH:
undetectable		 5z86J-3ujiH:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3uji FAB REGION OF THE
HEAVY CHAIN OF
ANTI-HIV-1 V3
MONOCLONAL ANTIBODY
2558
(Homo
sapiens) 		5 / 12 VAL H 163
VAL H 182
SER H 180
ASN H 197
ASN H 155
 None
 1.43A 6h7mB-3ujiH:
undetectable		 6h7mB-3ujiH:
18.14