SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ujk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 3ujk PROTEIN PHOSPHATASE
2C 77
(Arabidopsis
thaliana) 		4 / 7 SER A 266
ALA A 247
SER A 252
ALA A 254
 None
 0.91A 1k5qA-3ujkA:
undetectable
1k5qB-3ujkA:
2.5		 1k5qA-3ujkA:
19.45
1k5qB-3ujkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3ujk PROTEIN PHOSPHATASE
2C 77
(Arabidopsis
thaliana) 		4 / 5 SER A 232
SER A 234
VAL A 216
PHE A 213
 None
 1.49A 1oipA-3ujkA:
undetectable		 1oipA-3ujkA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_2
(PROTEASE)		 3ujk PROTEIN PHOSPHATASE
2C 77
(Arabidopsis
thaliana) 		5 / 9 ASP A 217
ASP A 317
LEU A 310
VAL A 172
ILE A 305
 None
 1.13A 3em4B-3ujkA:
undetectable		 3em4B-3ujkA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 3ujk PROTEIN PHOSPHATASE
2C 77
(Arabidopsis
thaliana) 		5 / 12 LEU A 182
TYR A 164
GLY A 162
SER A 234
CYH A 176
 None
 1.32A 3okxA-3ujkA:
undetectable		 3okxA-3ujkA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 3ujk PROTEIN PHOSPHATASE
2C 77
(Arabidopsis
thaliana) 		5 / 12 LEU A 182
TYR A 164
GLY A 162
SER A 234
CYH A 176
 None
 1.33A 3okxB-3ujkA:
undetectable		 3okxB-3ujkA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 3ujk PROTEIN PHOSPHATASE
2C 77
(Arabidopsis
thaliana) 		5 / 12 GLN A 171
GLY A 166
GLY A 169
SER A 304
ALA A 173
 None
MG  A 426 (-4.2A)
None
None
None
 1.30A 3t7sA-3ujkA:
undetectable		 3t7sA-3ujkA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_C_SAMC300_0
(PUTATIVE
METHYLTRANSFERASE)		 3ujk PROTEIN PHOSPHATASE
2C 77
(Arabidopsis
thaliana) 		5 / 12 GLN A 171
GLY A 166
GLY A 169
SER A 304
ALA A 173
 None
MG  A 426 (-4.2A)
None
None
None
 1.30A 3t7sC-3ujkA:
undetectable		 3t7sC-3ujkA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_C_SAMC401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 3ujk PROTEIN PHOSPHATASE
2C 77
(Arabidopsis
thaliana) 		5 / 11 SER A 252
GLY A 231
ASP A 307
LEU A 310
VAL A 314
 None
 1.30A 4pghC-3ujkA:
undetectable		 4pghC-3ujkA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3ujk PROTEIN PHOSPHATASE
2C 77
(Arabidopsis
thaliana) 		5 / 9 THR A 229
ALA A 226
ALA A 224
GLY A 168
GLY A 169
 None
 1.10A 4qwuK-3ujkA:
5.5
4qwuL-3ujkA:
5.1		 4qwuK-3ujkA:
20.62
4qwuL-3ujkA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3ujk PROTEIN PHOSPHATASE
2C 77
(Arabidopsis
thaliana) 		5 / 9 THR A 229
ALA A 226
ALA A 224
GLY A 168
GLY A 169
 None
 1.08A 4qwuY-3ujkA:
5.6
4qwuZ-3ujkA:
5.4		 4qwuY-3ujkA:
20.62
4qwuZ-3ujkA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT7_A_TOPA302_1
(RV2671)		 3ujk PROTEIN PHOSPHATASE
2C 77
(Arabidopsis
thaliana) 		5 / 11 ASN A 248
SER A 302
GLU A 276
GLU A 319
THR A 233
 None
None
None
None
MG  A 425 ( 4.5A)
 1.30A 4xt7A-3ujkA:
undetectable		 4xt7A-3ujkA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 3ujk PROTEIN PHOSPHATASE
2C 77
(Arabidopsis
thaliana) 		5 / 12 VAL A 235
ALA A 254
SER A 266
GLY A 338
LEU A 339
 None
None
None
MG  A 424 ( 4.8A)
None
 1.16A 5m5cB-3ujkA:
undetectable		 5m5cB-3ujkA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 3ujk PROTEIN PHOSPHATASE
2C 77
(Arabidopsis
thaliana) 		5 / 10 VAL A 235
ALA A 254
SER A 266
GLY A 338
LEU A 339
 None
None
None
MG  A 424 ( 4.8A)
None
 1.18A 5m5cE-3ujkA:
undetectable		 5m5cE-3ujkA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3ujk PROTEIN PHOSPHATASE
2C 77
(Arabidopsis
thaliana) 		5 / 12 VAL A 235
LEU A 332
ALA A 254
SER A 266
LEU A 339
 None
 1.30A 5nd4B-3ujkA:
undetectable		 5nd4B-3ujkA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZBD_A_TRPA501_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 3ujk PROTEIN PHOSPHATASE
2C 77
(Arabidopsis
thaliana) 		5 / 10 LEU A 310
TYR A 309
ASP A 307
VAL A 295
GLY A 297
 None
 1.38A 5zbdA-3ujkA:
undetectable		 5zbdA-3ujkA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZBD_B_TRPB501_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 3ujk PROTEIN PHOSPHATASE
2C 77
(Arabidopsis
thaliana) 		5 / 10 LEU A 310
TYR A 309
ASP A 307
VAL A 295
GLY A 297
 None
 1.41A 5zbdB-3ujkA:
undetectable		 5zbdB-3ujkA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3ujk PROTEIN PHOSPHATASE
2C 77
(Arabidopsis
thaliana) 		5 / 12 VAL A 406
SER A 405
VAL A 409
GLY A 114
VAL A 235
 None
 1.18A 6a94B-3ujkA:
undetectable		 6a94B-3ujkA:
20.73