SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ujp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_A_SALA3005_1
(XANTHINE
DEHYDROGENASE)		 3ujp MN TRANSPORTER
SUBUNIT
(Synechocystis
sp.
PCC
6803) 		5 / 9 GLU A 115
LEU A 114
THR A  62
VAL A  63
LEU A  64
 None
 1.46A 1fo4A-3ujpA:
0.5		 1fo4A-3ujpA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 3ujp MN TRANSPORTER
SUBUNIT
(Synechocystis
sp.
PCC
6803) 		4 / 7 ASN A 152
ASN A 110
HIS A  89
VAL A 294
 None
None
MN  A   1 (-3.3A)
None
 1.34A 1wu8A-3ujpA:
undetectable
1wu8C-3ujpA:
undetectable		 1wu8A-3ujpA:
21.34
1wu8C-3ujpA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)		 3ujp MN TRANSPORTER
SUBUNIT
(Synechocystis
sp.
PCC
6803) 		4 / 5 LEU A  58
PHE A 118
VAL A 128
ALA A 101
 None
 1.16A 2cizA-3ujpA:
undetectable		 2cizA-3ujpA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_1
(AAC(6')-IB)		 3ujp MN TRANSPORTER
SUBUNIT
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 136
TYR A 165
LEU A  64
TYR A 109
SER A 130
 None
 1.42A 2vqyA-3ujpA:
undetectable		 2vqyA-3ujpA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 3ujp MN TRANSPORTER
SUBUNIT
(Synechocystis
sp.
PCC
6803) 		4 / 6 LEU A 292
SER A 218
PHE A 267
ILE A 318
 None
 0.93A 3ko0S-3ujpA:
undetectable		 3ko0S-3ujpA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ujp MN TRANSPORTER
SUBUNIT
(Synechocystis
sp.
PCC
6803) 		5 / 12 VAL A 128
SER A 130
ALA A 172
VAL A  57
ALA A 104
 None
 1.08A 3ln1D-3ujpA:
undetectable		 3ln1D-3ujpA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 3ujp MN TRANSPORTER
SUBUNIT
(Synechocystis
sp.
PCC
6803) 		4 / 7 ASN A 152
ASP A 295
ILE A 240
HIS A  89
 None
MN  A   1 (-2.1A)
None
MN  A   1 (-3.3A)
 1.06A 3t01A-3ujpA:
undetectable		 3t01A-3ujpA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3ujp MN TRANSPORTER
SUBUNIT
(Synechocystis
sp.
PCC
6803) 		4 / 8 LEU A 108
VAL A  57
VAL A  78
GLN A  69
 None
 0.94A 4em2A-3ujpA:
undetectable		 4em2A-3ujpA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3ujp MN TRANSPORTER
SUBUNIT
(Synechocystis
sp.
PCC
6803) 		4 / 8 VAL A  71
TYR A 184
LEU A 106
LEU A 108
 None
 1.09A 4jtrA-3ujpA:
undetectable		 4jtrA-3ujpA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 3ujp MN TRANSPORTER
SUBUNIT
(Synechocystis
sp.
PCC
6803) 		5 / 12 LEU A 133
ILE A 107
ILE A 169
ALA A 172
PHE A 173
 None
 1.18A 4rp8C-3ujpA:
1.4		 4rp8C-3ujpA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 3ujp MN TRANSPORTER
SUBUNIT
(Synechocystis
sp.
PCC
6803) 		4 / 6 HIS A  89
GLY A  90
GLU A  87
ASN A 241
 MN  A   1 (-3.3A)
None
None
MN  A   1 (-4.2A)
 1.22A 4zbqA-3ujpA:
undetectable		 4zbqA-3ujpA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3ujp MN TRANSPORTER
SUBUNIT
(Synechocystis
sp.
PCC
6803) 		4 / 7 ALA A 286
THR A 284
VAL A 254
LYS A 259
 None
 1.22A 5ecnA-3ujpA:
undetectable		 5ecnA-3ujpA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3ujp MN TRANSPORTER
SUBUNIT
(Synechocystis
sp.
PCC
6803) 		4 / 5 TYR A 191
PRO A 159
GLY A 221
LEU A 310
 None
 0.95A 5eslA-3ujpA:
undetectable		 5eslA-3ujpA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ujp MN TRANSPORTER
SUBUNIT
(Synechocystis
sp.
PCC
6803) 		5 / 12 VAL A 128
SER A 130
ALA A 172
VAL A  57
ALA A 104
 None
 1.12A 5kirB-3ujpA:
undetectable		 5kirB-3ujpA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 3ujp MN TRANSPORTER
SUBUNIT
(Synechocystis
sp.
PCC
6803) 		3 / 3 MET A 232
GLU A 207
ARG A 214
 None
 1.11A 5tjzA-3ujpA:
3.1		 5tjzA-3ujpA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 3ujp MN TRANSPORTER
SUBUNIT
(Synechocystis
sp.
PCC
6803) 		4 / 7 ASP A 179
ASN A 180
ALA A 181
GLU A 175
 CAC  A2327 (-2.8A)
None
None
None
 0.91A 6ci6A-3ujpA:
1.9		 6ci6A-3ujpA:
13.68