SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ujq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3ujq LEGUME LECTIN
(Lablab
purpureus) 		4 / 4 ILE A 189
LEU A 219
VAL A 143
ILE A 164
 None
 0.88A 1fm6D-3ujqA:
undetectable		 1fm6D-3ujqA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 3ujq LEGUME LECTIN
(Lablab
purpureus) 		4 / 6 LEU A 128
GLY A 126
ASN A 152
ILE A 169
 None
GAL  A 301 ( 3.4A)
CA  A 303 (-3.6A)
None
 0.90A 1xf1B-3ujqA:
undetectable		 1xf1B-3ujqA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3ujq LEGUME LECTIN
(Lablab
purpureus) 		4 / 6 PHE A 127
ILE A 169
GLY A 154
GLY A 153
 None
 0.82A 2qx6A-3ujqA:
undetectable
2qx6B-3ujqA:
undetectable		 2qx6A-3ujqA:
22.87
2qx6B-3ujqA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 3ujq LEGUME LECTIN
(Lablab
purpureus) 		5 / 11 LEU A 197
VAL A 217
ILE A  79
VAL A 143
ILE A 164
 None
 1.12A 2uxoB-3ujqA:
undetectable		 2uxoB-3ujqA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 3ujq LEGUME LECTIN
(Lablab
purpureus) 		4 / 6 THR A  86
VAL A  87
LEU A 256
SER A 193
 None
 1.23A 3b6rB-3ujqA:
undetectable		 3b6rB-3ujqA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 3ujq LEGUME LECTIN
(Lablab
purpureus) 		4 / 7 SER A  28
LEU A 188
ALA A  91
SER A 251
 None
 0.83A 3cfqA-3ujqA:
undetectable
3cfqB-3ujqA:
undetectable		 3cfqA-3ujqA:
18.77
3cfqB-3ujqA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_B_C2FB302_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3ujq LEGUME LECTIN
(Lablab
purpureus) 		5 / 12 ASP A 148
ASP A 156
ASN A 152
GLY A 125
ARG A  70
 CA  A 303 ( 3.0A)
MN  A 304 ( 2.6A)
CA  A 303 (-3.6A)
GAL  A 301 (-3.6A)
None
 1.36A 4djeB-3ujqA:
undetectable		 4djeB-3ujqA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 3ujq LEGUME LECTIN
(Lablab
purpureus) 		3 / 3 SER A 138
TYR A 136
PRO A 224
 None
 0.77A 4k8cA-3ujqA:
undetectable		 4k8cA-3ujqA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ujq LEGUME LECTIN
(Lablab
purpureus) 		3 / 3 SER A 138
TYR A 136
PRO A 224
 None
 0.79A 4kahA-3ujqA:
undetectable		 4kahA-3ujqA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ujq LEGUME LECTIN
(Lablab
purpureus) 		3 / 3 SER A 138
TYR A 136
PRO A 224
 None
 0.78A 4kahB-3ujqA:
undetectable		 4kahB-3ujqA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ujq LEGUME LECTIN
(Lablab
purpureus) 		3 / 3 SER A 138
TYR A 136
PRO A 224
 None
 0.76A 4kanA-3ujqA:
undetectable		 4kanA-3ujqA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ujq LEGUME LECTIN
(Lablab
purpureus) 		3 / 3 SER A 138
TYR A 136
PRO A 224
 None
 0.76A 4kanB-3ujqA:
undetectable		 4kanB-3ujqA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ujq LEGUME LECTIN
(Lablab
purpureus) 		3 / 3 SER A 138
TYR A 136
PRO A 224
 None
 0.77A 4kbeA-3ujqA:
undetectable		 4kbeA-3ujqA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ujq LEGUME LECTIN
(Lablab
purpureus) 		3 / 3 SER A 138
TYR A 136
PRO A 224
 None
 0.79A 4kbeB-3ujqA:
undetectable		 4kbeB-3ujqA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ujq LEGUME LECTIN
(Lablab
purpureus) 		3 / 3 SER A 138
TYR A 136
PRO A 224
 None
 0.77A 4lbgA-3ujqA:
undetectable		 4lbgA-3ujqA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ujq LEGUME LECTIN
(Lablab
purpureus) 		3 / 3 SER A 138
TYR A 136
PRO A 224
 None
 0.78A 4lbgB-3ujqA:
undetectable		 4lbgB-3ujqA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 3ujq LEGUME LECTIN
(Lablab
purpureus) 		4 / 7 THR A 235
GLY A 109
ALA A 233
ILE A  54
 None
 0.91A 4txnD-3ujqA:
undetectable		 4txnD-3ujqA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 3ujq LEGUME LECTIN
(Lablab
purpureus) 		3 / 3 LYS A 124
ASP A 123
ARG A  70
 None
 0.96A 5jwaA-3ujqA:
undetectable
5jwaH-3ujqA:
undetectable		 5jwaA-3ujqA:
20.88
5jwaH-3ujqA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3ujq LEGUME LECTIN
(Lablab
purpureus) 		4 / 8 ASP A 148
HIS A 204
ARG A 160
HIS A 161
 CA  A 303 ( 3.0A)
None
None
MN  A 304 (-4.0A)
 1.19A 6mn4A-3ujqA:
undetectable		 6mn4A-3ujqA:
23.18