SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uki'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 3uki OXYR
(Porphyromonas
gingivalis) 		3 / 3 ALA A 227
VAL A 232
TRP A 192
 None
 0.92A 1bdwA-3ukiA:
undetectable
1bdwB-3ukiA:
undetectable		 1bdwA-3ukiA:
8.49
1bdwB-3ukiA:
8.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3uki OXYR
(Porphyromonas
gingivalis) 		5 / 10 LEU A 105
ALA A 102
ILE A 101
VAL A 124
LEU A  93
 None
 1.17A 1xp0A-3ukiA:
undetectable		 1xp0A-3ukiA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 3uki OXYR
(Porphyromonas
gingivalis) 		5 / 11 LEU A 105
VAL A 109
LEU A 282
VAL A 124
ILE A 122
 None
 1.17A 2uxoB-3ukiA:
undetectable		 2uxoB-3ukiA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3uki OXYR
(Porphyromonas
gingivalis) 		4 / 4 LEU A 106
PRO A 107
LEU A 105
ARG A 267
 None
 1.39A 3hcoA-3ukiA:
undetectable		 3hcoA-3ukiA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 3uki OXYR
(Porphyromonas
gingivalis) 		4 / 5 GLU A 233
SER A 252
ARG A 230
SER A 250
 None
 1.39A 4k17B-3ukiA:
undetectable		 4k17B-3ukiA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_D_ACTD403_0
(PROTON-GATED ION
CHANNEL)		 3uki OXYR
(Porphyromonas
gingivalis) 		4 / 4 ILE A 241
ARG A 230
TYR A 168
GLU A 233
 None
 1.24A 4zzbD-3ukiA:
undetectable		 4zzbD-3ukiA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 3uki OXYR
(Porphyromonas
gingivalis) 		4 / 5 ILE A 241
ARG A 230
TYR A 168
GLU A 233
 None
 1.28A 4zzcE-3ukiA:
undetectable		 4zzcE-3ukiA:
21.45