SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ukm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FBM_B_RTLB951_1 (PROTEIN (CARTILAGE OLIGOMERIC MATRIX PROTEIN))	3ukm	POTASSIUM CHANNEL SUBFAMILY K MEMBER 1 (Homo sapiens)	4 / 4	THR A 105 LEU A 108 VAL A 35 LEU A 32	None	1.06A	1fbmB-3ukmA: undetectable	1fbmB-3ukmA: 9.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MOG_A_RBFA200_1 (DODECIN)	3ukm	POTASSIUM CHANNEL SUBFAMILY K MEMBER 1 (Homo sapiens)	3 / 3	PHE A 110 TRP A 102 GLU A 49	None	1.07A	1mogA-3ukmA: undetectable	1mogA-3ukmA: 12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA3_A_STRA1001_2 (MINERALOCORTICOID RECEPTOR)	3ukm	POTASSIUM CHANNEL SUBFAMILY K MEMBER 1 (Homo sapiens)	4 / 4	LEU A 146 LEU A 115 SER A 116 LEU A 257	None	1.06A	1ya3A-3ukmA: undetectable	1ya3A-3ukmA: 23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZB8_A_IMNA800_1 (PROSTAGLANDIN REDUCTASE 2)	3ukm	POTASSIUM CHANNEL SUBFAMILY K MEMBER 1 (Homo sapiens)	5 / 9	THR A 117 PHE A 195 TYR A 252 LEU A 261 VAL A 262	K A 4 ( 3.9A) None None None None	1.44A	2zb8A-3ukmA: undetectable	2zb8A-3ukmA: 22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FHZ_A_REAA602_1 (ALDEHYDE DEHYDROGENASE FAMILY 1 MEMBER A3)	3ukm	POTASSIUM CHANNEL SUBFAMILY K MEMBER 1 (Homo sapiens)	5 / 12	ILE A 249 GLY A 234 ARG A 242 PHE A 218 THR A 118	None	1.41A	5fhzA-3ukmA: undetectable	5fhzA-3ukmA: 20.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FBM_B_RTLB951_1","PROTEIN (CARTILAGE OLIGOMERIC MATRIX PROTEIN)","3ukm","POTASSIUM CHANNEL SUBFAMILY K MEMBER 1","Homo sapiens",4,"THR A 105;LEU A 108;VAL A  35;LEU A  32","None","1.06A","1fbmB-3ukmA:undetectable","1fbmB-3ukmA:9.67"],["1MOG_A_RBFA200_1","DODECIN","3ukm","POTASSIUM CHANNEL SUBFAMILY K MEMBER 1","Homo sapiens",3,"PHE A 110;TRP A 102;GLU A  49","None","1.07A","1mogA-3ukmA:undetectable","1mogA-3ukmA:12.89"],["1YA3_A_STRA1001_2","MINERALOCORTICOID RECEPTOR","3ukm","POTASSIUM CHANNEL SUBFAMILY K MEMBER 1","Homo sapiens",4,"LEU A 146;LEU A 115;SER A 116;LEU A 257","None","1.06A","1ya3A-3ukmA:undetectable","1ya3A-3ukmA:23.71"],["2ZB8_A_IMNA800_1","PROSTAGLANDIN REDUCTASE 2","3ukm","POTASSIUM CHANNEL SUBFAMILY K MEMBER 1","Homo sapiens",5,"THR A 117;PHE A 195;TYR A 252;LEU A 261;VAL A 262","  K A   4 ( 3.9A);None;None;None;None","1.44A","2zb8A-3ukmA:undetectable","2zb8A-3ukmA:22.10"],["5FHZ_A_REAA602_1","ALDEHYDE DEHYDROGENASE FAMILY 1 MEMBER A3","3ukm","POTASSIUM CHANNEL SUBFAMILY K MEMBER 1","Homo sapiens",5,"ILE A 249;GLY A 234;ARG A 242;PHE A 218;THR A 118","None","1.41A","5fhzA-3ukmA:undetectable","5fhzA-3ukmA:20.00"]]