SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ukn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 3ukn NOVEL PROTEIN
SIMILAR TO
VERTEBRATE POTASSIUM
VOLTAGE-GATED
CHANNEL, SUBFAMILY H
(EAG-RELATED) FAMILY
(Danio
rerio) 		4 / 8 PHE A 730
LEU A 688
LEU A 738
LEU A 682
 None
 0.98A 2bfpB-3uknA:
undetectable		 2bfpB-3uknA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 3ukn NOVEL PROTEIN
SIMILAR TO
VERTEBRATE POTASSIUM
VOLTAGE-GATED
CHANNEL, SUBFAMILY H
(EAG-RELATED) FAMILY
(Danio
rerio) 		3 / 3 SER A 631
TYR A 723
ASP A 601
 None
 0.85A 4rp8C-3uknA:
undetectable		 4rp8C-3uknA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)		 3ukn NOVEL PROTEIN
SIMILAR TO
VERTEBRATE POTASSIUM
VOLTAGE-GATED
CHANNEL, SUBFAMILY H
(EAG-RELATED) FAMILY
(Danio
rerio) 		4 / 6 ARG A 717
GLY A 715
SER A 712
LEU A 713
 None
 1.23A 5bphA-3uknA:
undetectable		 5bphA-3uknA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 3ukn NOVEL PROTEIN
SIMILAR TO
VERTEBRATE POTASSIUM
VOLTAGE-GATED
CHANNEL, SUBFAMILY H
(EAG-RELATED) FAMILY
(Danio
rerio) 		4 / 6 PHE A 621
LEU A 620
SER A 732
THR A 689
 None
 1.03A 6f88A-3uknA:
undetectable		 6f88A-3uknA:
17.54