SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ulp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EIZ_A_SAMA301_1 (FTSJ)	3ulp	SINGLE-STRAND BINDING PROTEIN (Plasmodium falciparum)	3 / 3	ASP A 138 ASP A 189 ASP A 143	None	0.67A	1eizA-3ulpA: undetectable	1eizA-3ulpA: 18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W9H_A_TOPA1160_1 (DIHYDROFOLATE REDUCTASE)	3ulp	SINGLE-STRAND BINDING PROTEIN (Plasmodium falciparum)	5 / 10	LEU A 111 LEU A 183 VAL A 155 ILE A 145 PHE A 109	None	1.10A	2w9hA-3ulpA: undetectable	2w9hA-3ulpA: 22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DOU_A_SAMA1_1 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J)	3ulp	SINGLE-STRAND BINDING PROTEIN (Plasmodium falciparum)	3 / 3	ASP A 138 ASP A 189 ASP A 143	None	0.66A	3douA-3ulpA: undetectable	3douA-3ulpA: 20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I8F_A_ML1A210_1 (PHENOLIC OXIDATIVE COUPLING PROTEIN)	3ulp	SINGLE-STRAND BINDING PROTEIN (Plasmodium falciparum)	5 / 12	LEU A 82 HIS A 162 TYR A 156 GLY A 188 LYS A 187	None	1.48A	5i8fA-3ulpA: undetectable	5i8fA-3ulpA: 20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NOO_A_D16A402_1 (THYMIDYLATE SYNTHASE)	3ulp	SINGLE-STRAND BINDING PROTEIN (Plasmodium falciparum)	4 / 7	TYR A 137 ILE A 182 GLY A 188 TYR A 156	None	0.87A	5nooA-3ulpA: undetectable	5nooA-3ulpA: 16.88

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EIZ_A_SAMA301_1","FTSJ","3ulp","SINGLE-STRAND BINDING PROTEIN","Plasmodium falciparum",3,"ASP A 138;ASP A 189;ASP A 143","None","0.67A","1eizA-3ulpA:undetectable","1eizA-3ulpA:18.13"],["2W9H_A_TOPA1160_1","DIHYDROFOLATE REDUCTASE","3ulp","SINGLE-STRAND BINDING PROTEIN","Plasmodium falciparum",5,"LEU A 111;LEU A 183;VAL A 155;ILE A 145;PHE A 109","None","1.10A","2w9hA-3ulpA:undetectable","2w9hA-3ulpA:22.84"],["3DOU_A_SAMA1_1","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","3ulp","SINGLE-STRAND BINDING PROTEIN","Plasmodium falciparum",3,"ASP A 138;ASP A 189;ASP A 143","None","0.66A","3douA-3ulpA:undetectable","3douA-3ulpA:20.43"],["5I8F_A_ML1A210_1","PHENOLIC OXIDATIVE COUPLING PROTEIN","3ulp","SINGLE-STRAND BINDING PROTEIN","Plasmodium falciparum",5,"LEU A  82;HIS A 162;TYR A 156;GLY A 188;LYS A 187","None","1.48A","5i8fA-3ulpA:undetectable","5i8fA-3ulpA:20.86"],["5NOO_A_D16A402_1","THYMIDYLATE SYNTHASE","3ulp","SINGLE-STRAND BINDING PROTEIN","Plasmodium falciparum",4,"TYR A 137;ILE A 182;GLY A 188;TYR A 156","None","0.87A","5nooA-3ulpA:undetectable","5nooA-3ulpA:16.88"]]