SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ulv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JWQ_B_VIAB901_1 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA)	3ulv	FAB12 HEAVY CHAIN (Homo sapiens)	5 / 11	TYR D 154 HIS D 209 LEU D 117 ALA D 177 THR D 94	None	1.21A	3jwqB-3ulvD: undetectable 3jwqC-3ulvD: undetectable	3jwqB-3ulvD: 19.17 3jwqC-3ulvD: 19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NYA_A_JTZA1203_1 (BETA-2 ADRENERGIC RECEPTOR, LYSOZYME)	3ulv	FAB12 HEAVY CHAIN (Homo sapiens)	5 / 12	VAL D 172 VAL D 191 SER D 189 ASN D 206 ASN D 164	None	1.39A	3nyaA-3ulvD: undetectable	3nyaA-3ulvD: 17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AX8_A_SAMA1474_0 (WBDD)	3ulv	FAB12 HEAVY CHAIN (Homo sapiens)	5 / 12	GLY D 37 ALA D 100 GLN D 6 ILE D 73 ILE D 71	None	0.91A	4ax8A-3ulvD: undetectable	4ax8A-3ulvD: 17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DRZ_A_H8JA1206_0 (5HT2B RECEPTOR, BRIL CHIMERA)	3ulv	FAB12 HEAVY CHAIN (Homo sapiens)	5 / 12	VAL D 216 THR D 214 VAL D 220 GLY D 127 VAL D 161	None	0.99A	6drzA-3ulvD: undetectable	6drzA-3ulvD: 19.22

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3JWQ_B_VIAB901_1","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA;CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA","3ulv","FAB12 HEAVY CHAIN","Homo sapiens",5,"TYR D 154;HIS D 209;LEU D 117;ALA D 177;THR D  94","None","1.21A","3jwqB-3ulvD:undetectable;3jwqC-3ulvD:undetectable","3jwqB-3ulvD:19.17;3jwqC-3ulvD:19.17"],["3NYA_A_JTZA1203_1","BETA-2 ADRENERGIC RECEPTOR, LYSOZYME","3ulv","FAB12 HEAVY CHAIN","Homo sapiens",5,"VAL D 172;VAL D 191;SER D 189;ASN D 206;ASN D 164","None","1.39A","3nyaA-3ulvD:undetectable","3nyaA-3ulvD:17.89"],["4AX8_A_SAMA1474_0","WBDD","3ulv","FAB12 HEAVY CHAIN","Homo sapiens",5,"GLY D  37;ALA D 100;GLN D   6;ILE D  73;ILE D  71","None","0.91A","4ax8A-3ulvD:undetectable","4ax8A-3ulvD:17.74"],["6DRZ_A_H8JA1206_0","5HT2B RECEPTOR, BRIL CHIMERA","3ulv","FAB12 HEAVY CHAIN","Homo sapiens",5,"VAL D 216;THR D 214;VAL D 220;GLY D 127;VAL D 161","None","0.99A","6drzA-3ulvD:undetectable","6drzA-3ulvD:19.22"]]