SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uma'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		4 / 8 THR A  48
GLY A 147
GLY A 153
SER A 152
 None
 0.75A 1d0vA-3umaA:
undetectable		 1d0vA-3umaA:
21.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		5 / 10 PRO A  42
THR A  46
PRO A  47
CYH A  49
ARG A 127
 None
 0.15A 1h4oA-3umaA:
27.5
1h4oB-3umaA:
27.6		 1h4oA-3umaA:
37.10
1h4oB-3umaA:
37.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		5 / 8 PRO A  42
THR A  46
PRO A  47
CYH A  49
ARG A 127
 None
 0.19A 1h4oB-3umaA:
27.6		 1h4oB-3umaA:
37.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_C_BEZC1162_0
(PEROXIREDOXIN 5)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		5 / 9 PRO A  42
THR A  46
PRO A  47
CYH A  49
ARG A 127
 None
 0.17A 1h4oC-3umaA:
27.4
1h4oD-3umaA:
27.5		 1h4oC-3umaA:
37.10
1h4oD-3umaA:
37.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_D_BEZD1162_0
(PEROXIREDOXIN 5)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		5 / 9 PRO A  42
THR A  46
PRO A  47
CYH A  49
ARG A 127
 None
 0.16A 1h4oD-3umaA:
27.5		 1h4oD-3umaA:
37.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_E_BEZE1162_0
(PEROXIREDOXIN 5)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		5 / 9 PRO A  42
THR A  46
PRO A  47
CYH A  49
ARG A 127
 None
 0.17A 1h4oE-3umaA:
27.5
1h4oF-3umaA:
27.5		 1h4oE-3umaA:
37.10
1h4oF-3umaA:
37.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_F_BEZF1162_0
(PEROXIREDOXIN 5)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		5 / 9 PRO A  42
THR A  46
PRO A  47
CYH A  49
ARG A 127
 None
 0.16A 1h4oF-3umaA:
27.5		 1h4oF-3umaA:
37.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		5 / 8 PRO A  42
THR A  46
PRO A  47
CYH A  49
ARG A 127
 None
 0.16A 1h4oG-3umaA:
27.6		 1h4oG-3umaA:
37.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_H_BEZH1162_0
(PEROXIREDOXIN 5)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		5 / 9 PRO A  42
THR A  46
PRO A  47
CYH A  49
ARG A 127
 None
 0.18A 1h4oH-3umaA:
27.5		 1h4oH-3umaA:
37.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HD2_A_BEZA201_0
(PEROXIREDOXIN 5
RESIDUES 54-214)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		5 / 9 PRO A  42
THR A  46
PRO A  47
CYH A  49
ARG A 127
 None
 0.17A 1hd2A-3umaA:
27.3		 1hd2A-3umaA:
37.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		4 / 8 THR A  48
GLY A 147
GLY A 153
SER A 152
 None
 0.76A 1jhaA-3umaA:
undetectable		 1jhaA-3umaA:
21.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		5 / 8 PRO A  42
THR A  46
PRO A  47
CYH A  49
ARG A 127
 None
 0.17A 1oc3A-3umaA:
27.3		 1oc3A-3umaA:
40.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OC3_B_BEZB201_0
(PEROXIREDOXIN 5)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		5 / 9 PRO A  42
THR A  46
PRO A  47
CYH A  49
ARG A 127
 None
 0.15A 1oc3B-3umaA:
27.5		 1oc3B-3umaA:
40.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		5 / 11 VAL A 132
PHE A  31
ILE A 110
LEU A   9
PHE A 106
 None
 0.74A 1z11A-3umaA:
undetectable		 1z11A-3umaA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		5 / 11 VAL A 132
PHE A  31
ILE A 110
LEU A   9
PHE A 106
 None
 0.73A 1z11B-3umaA:
undetectable		 1z11B-3umaA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_A_GBNA2414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		4 / 8 GLY A  56
GLY A 153
THR A 150
ALA A 149
 None
 0.59A 2ej3A-3umaA:
undetectable		 2ej3A-3umaA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		4 / 8 PRO A  42
THR A  46
PRO A  47
ARG A 127
 None
 0.49A 2v32C-3umaA:
18.4
2v32D-3umaA:
19.5		 2v32C-3umaA:
21.90
2v32D-3umaA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		4 / 8 PRO A  42
THR A  46
PRO A  47
ARG A 127
 None
 0.55A 2v41C-3umaA:
19.3
2v41D-3umaA:
19.7		 2v41C-3umaA:
21.90
2v41D-3umaA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		4 / 8 PRO A  42
THR A  46
PRO A  47
ARG A 127
 None
 0.54A 2v41C-3umaA:
19.3
2v41D-3umaA:
19.7		 2v41C-3umaA:
21.90
2v41D-3umaA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		4 / 8 PRO A  42
THR A  46
PRO A  47
ARG A 127
 None
 0.55A 2v41G-3umaA:
18.1
2v41H-3umaA:
18.3		 2v41G-3umaA:
21.90
2v41H-3umaA:
21.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		5 / 10 PRO A  42
THR A  46
PRO A  47
CYH A  49
ARG A 127
 None
 0.17A 2vl2A-3umaA:
27.4
2vl2C-3umaA:
22.7		 2vl2A-3umaA:
40.43
2vl2C-3umaA:
40.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 ILE A 110
ALA A 109
ASN A  11
ALA A 104
VAL A 137
 None
 1.09A 3e00A-3umaA:
undetectable		 3e00A-3umaA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		5 / 9 ALA A 105
VAL A  77
GLY A 111
ILE A   3
VAL A  75
 None
 1.12A 3ekvB-3umaA:
undetectable		 3ekvB-3umaA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		4 / 8 ASP A  62
LEU A  65
ASP A  71
ILE A  72
 None
 0.94A 4k0bA-3umaA:
undetectable		 4k0bA-3umaA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		4 / 8 ASP A  62
LEU A  65
ASP A  71
ILE A  72
 None
 0.93A 4l7iA-3umaA:
undetectable		 4l7iA-3umaA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YOA_A_017A100_1
(HIV-1 PROTEASE)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		4 / 6 ASP A 115
THR A  46
PRO A  47
THR A  48
 None
 0.80A 4yoaA-3umaA:
undetectable		 4yoaA-3umaA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		3 / 3 THR A  48
ALA A 149
ASN A  52
 None
 0.61A 5ersA-3umaA:
undetectable		 5ersA-3umaA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		4 / 4 GLY A   6
ALA A   4
MET A 130
THR A   2
 None
 1.23A 5n0sB-3umaA:
undetectable		 5n0sB-3umaA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 GLY A  43
VAL A  41
PHE A  39
GLY A  91
GLY A  92
 None
 1.08A 6brdB-3umaA:
undetectable		 6brdB-3umaA:
19.32