SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3umv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		3 / 4 VAL A 174
TRP A  54
TRP A 175
 None
 1.11A 1gmkC-3umvA:
undetectable
1gmkD-3umvA:
undetectable		 1gmkC-3umvA:
5.24
1gmkD-3umvA:
5.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		5 / 12 LEU A 206
ASN A  53
LEU A 109
VAL A  40
ALA A  73
 None
 1.12A 1n5xA-3umvA:
undetectable		 1n5xA-3umvA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		5 / 12 LEU A 206
ASN A  53
LEU A 109
VAL A  40
ALA A  73
 None
 1.12A 1n5xB-3umvA:
undetectable		 1n5xB-3umvA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		4 / 7 PHE A  77
ALA A 146
ILE A 121
PRO A 118
 URE  A 904 (-4.6A)
None
None
None
 0.99A 1oniA-3umvA:
undetectable
1oniB-3umvA:
undetectable		 1oniA-3umvA:
16.89
1oniB-3umvA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		4 / 6 PHE A  77
ALA A 146
ILE A 121
PRO A 118
 URE  A 904 (-4.6A)
None
None
None
 1.11A 1oniH-3umvA:
undetectable
1oniI-3umvA:
0.0		 1oniH-3umvA:
16.89
1oniI-3umvA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		4 / 7 ILE A 121
PRO A 118
PHE A  77
ALA A 146
 None
None
URE  A 904 (-4.6A)
None
 0.94A 1oniG-3umvA:
undetectable
1oniI-3umvA:
undetectable		 1oniG-3umvA:
16.89
1oniI-3umvA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		5 / 11 GLY A 436
GLY A 428
ASP A 422
TYR A 434
VAL A 435
 FAD  A 801 (-3.4A)
FAD  A 801 (-3.2A)
None
None
None
 1.19A 1pg2A-3umvA:
2.4		 1pg2A-3umvA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		5 / 12 LEU A  94
LEU A  97
LEU A 100
ALA A 101
VAL A  72
 None
 1.01A 1s9pC-3umvA:
undetectable		 1s9pC-3umvA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_A_NCAA1501_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		4 / 7 ARG A 459
ALA A 185
ARG A 323
ASP A 446
 None
None
FAD  A 801 (-3.4A)
None
 1.14A 2e5dA-3umvA:
undetectable
2e5dB-3umvA:
undetectable		 2e5dA-3umvA:
20.87
2e5dB-3umvA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_B_NCAB1502_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		4 / 7 ASP A 446
ARG A 459
ALA A 185
ARG A 323
 None
None
None
FAD  A 801 (-3.4A)
 1.19A 2e5dA-3umvA:
undetectable
2e5dB-3umvA:
undetectable		 2e5dA-3umvA:
20.87
2e5dB-3umvA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		5 / 9 LEU A 414
PRO A 410
LEU A 404
LEU A 351
ALA A 347
 None
 1.15A 2vcvI-3umvA:
undetectable		 2vcvI-3umvA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		5 / 12 ASP A 430
PHE A 137
ASP A 167
VAL A 174
ASN A 170
 FAD  A 801 ( 4.2A)
None
None
None
None
 1.14A 2x2iD-3umvA:
undetectable		 2x2iD-3umvA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		3 / 3 MET A 395
VAL A 435
GLU A 319
 None
None
FAD  A 801 (-4.7A)
 0.88A 2x9gA-3umvA:
2.8		 2x9gA-3umvA:
20.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XRZ_A_ACTA1468_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		4 / 5 LYS A 401
LYS A 402
GLU A 405
TYR A 460
 None
None
EDO  A 706 (-3.7A)
EDO  A 706 (-4.7A)
 0.48A 2xrzA-3umvA:
51.7		 2xrzA-3umvA:
45.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_1
(PROTEASE)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		5 / 10 LEU A  57
ALA A 168
ASP A 136
GLY A 291
ILE A 293
 None
 1.11A 3el5A-3umvA:
undetectable		 3el5A-3umvA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		4 / 6 ARG A 214
GLU A 215
PHE A 112
PRO A 110
 None
None
URE  A 905 (-4.8A)
None
 1.42A 3gclA-3umvA:
undetectable		 3gclA-3umvA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		4 / 7 TYR A 363
GLU A 405
TYR A 398
TYR A 460
 None
EDO  A 706 (-3.7A)
None
EDO  A 706 (-4.7A)
 1.31A 3ku9B-3umvA:
undetectable		 3ku9B-3umvA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O01_B_DXCB1_0
(CELL INVASION
PROTEIN SIPD)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		5 / 9 ARG A 297
ILE A 293
ALA A 299
LEU A 288
VAL A 171
 None
None
None
FAD  A 801 (-4.4A)
None
 1.22A 3o01A-3umvA:
0.0
3o01B-3umvA:
undetectable		 3o01A-3umvA:
21.71
3o01B-3umvA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		3 / 3 GLU A 215
PHE A 112
GLN A 216
 None
URE  A 905 (-4.8A)
None
 0.91A 3r55A-3umvA:
undetectable		 3r55A-3umvA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		4 / 5 LEU A 284
GLY A 283
PHE A 260
PHE A 316
 None
EDO  A 701 ( 3.2A)
None
None
 1.15A 3smtA-3umvA:
undetectable		 3smtA-3umvA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		3 / 3 ARG A 272
ASP A 446
GLN A 447
 None
None
EDO  A 703 (-4.7A)
 0.82A 4azsA-3umvA:
undetectable		 4azsA-3umvA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		5 / 12 LEU A  94
LEU A  97
LEU A 100
ALA A 101
ALA A  73
 None
 0.70A 4fn9A-3umvA:
undetectable		 4fn9A-3umvA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		4 / 6 ASP A  47
ASP A 167
ASP A 430
ASN A 170
 None
None
FAD  A 801 ( 4.2A)
None
 1.33A 4gkhJ-3umvA:
undetectable		 4gkhJ-3umvA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		4 / 5 LEU A 482
TRP A 241
ILE A 426
ASN A 421
 None
EDO  A 701 (-4.6A)
None
FAD  A 801 (-3.0A)
 1.05A 4i00A-3umvA:
undetectable		 4i00A-3umvA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_E_IPHE101_0
(INSULIN)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		5 / 11 LEU A 206
HIS A  58
LEU A  57
ALA A  60
LEU A  70
 None
 1.06A 4p65E-3umvA:
undetectable
4p65F-3umvA:
undetectable
4p65J-3umvA:
undetectable
4p65L-3umvA:
undetectable		 4p65E-3umvA:
4.17
4p65F-3umvA:
6.14
4p65J-3umvA:
6.14
4p65L-3umvA:
6.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		5 / 10 GLY A 190
PHE A 188
LEU A 326
SER A 178
ALA A 179
 None
 1.19A 4wnuD-3umvA:
undetectable		 4wnuD-3umvA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJQ_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		5 / 11 LEU A 326
GLU A 319
ASP A 427
ASN A 421
GLU A 425
 None
FAD  A 801 (-4.7A)
FAD  A 801 (-3.5A)
FAD  A 801 (-3.0A)
None
 1.16A 4zjqA-3umvA:
undetectable		 4zjqA-3umvA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		5 / 12 LEU A 300
ALA A 302
LEU A 253
LEU A 261
LEU A 320
 None
None
None
None
FAD  A 801 (-4.6A)
 1.20A 4zn7A-3umvA:
undetectable		 4zn7A-3umvA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		3 / 3 ASN A 462
ALA A 464
ARG A 468
 None
 0.62A 5cvtB-3umvA:
2.4		 5cvtB-3umvA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		5 / 12 VAL A 313
ASP A 314
LEU A 288
ALA A 302
LEU A 200
 None
None
FAD  A 801 (-4.4A)
None
None
 1.41A 5nd2B-3umvA:
undetectable		 5nd2B-3umvA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_A_ACTA703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		4 / 6 ARG A 155
ARG A 156
ALA A 158
PRO A 159
 None
 1.19A 5odqA-3umvA:
undetectable		 5odqA-3umvA:
23.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_1
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		5 / 12 LEU A 444
GLY A 443
GLY A 436
LEU A 326
ALA A 417
 None
None
FAD  A 801 (-3.4A)
None
None
 0.92A 5xv7A-3umvA:
undetectable		 5xv7A-3umvA:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		5 / 12 LEU A 225
ILE A 226
CYH A 230
PHE A  81
PHE A 114
 URE  A 903 (-4.5A)
None
None
None
URE  A 905 (-4.0A)
 1.11A 6a7pA-3umvA:
undetectable		 6a7pA-3umvA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		4 / 4 HIS A 164
VAL A  40
LEU A  62
ALA A 162
 None
 1.24A 6d8pB-3umvA:
2.1		 6d8pB-3umvA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYN_A_HSMA901_0
(EBONY)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		4 / 4 GLU A 232
VAL A 229
LEU A 225
THR A 115
 EDO  A 708 ( 4.4A)
None
URE  A 903 (-4.5A)
None
 1.42A 6dynA-3umvA:
undetectable		 6dynA-3umvA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE
(Oryza
sativa) 		4 / 5 GLU A 232
VAL A 229
LEU A 225
THR A 115
 EDO  A 708 ( 4.4A)
None
URE  A 903 (-4.5A)
None
 1.41A 6dyoA-3umvA:
undetectable		 6dyoA-3umvA:
11.04