SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3un1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3un1 PROBABLE
OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		4 / 4 THR A 149
LEU A 153
VAL A 156
LEU A 160
 None
 0.83A 1fbmB-3un1A:
undetectable		 1fbmB-3un1A:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3un1 PROBABLE
OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		4 / 4 THR A 149
LEU A 153
VAL A 156
LEU A 160
 None
 0.59A 1fbmD-3un1A:
undetectable		 1fbmD-3un1A:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3un1 PROBABLE
OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		4 / 4 THR A 149
LEU A 153
VAL A 156
LEU A 160
 None
 0.97A 1mz9D-3un1A:
undetectable		 1mz9D-3un1A:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 3un1 PROBABLE
OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		4 / 8 HIS A 125
VAL A  77
LEU A 212
HIS A 216
 None
 0.91A 2it4A-3un1A:
undetectable		 2it4A-3un1A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 3un1 PROBABLE
OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 ASN A 154
ILE A 224
ALA A 173
ASN A  78
ILE A 129
 None
 1.12A 3ddyA-3un1A:
undetectable		 3ddyA-3un1A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3un1 PROBABLE
OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		4 / 7 THR A  10
VAL A  32
THR A  34
VAL A  49
 None
 0.54A 3em0B-3un1A:
undetectable		 3em0B-3un1A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3un1 PROBABLE
OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 9 GLN A   4
ASP A  74
ILE A  73
VAL A   8
VAL A  32
 None
 1.47A 3fi0L-3un1A:
undetectable		 3fi0L-3un1A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 3un1 PROBABLE
OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 ASN A 154
SER A 128
GLY A 152
ASN A  79
PHE A  83
 None
 1.41A 3r24A-3un1A:
5.5		 3r24A-3un1A:
undetectable