SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3un9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 12 LEU A 921
VAL A 929
SER A 734
ALA A 733
ASN A 731
 None
 1.14A 1eqbA-3un9A:
undetectable		 1eqbA-3un9A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 12 LEU A 921
VAL A 929
SER A 734
ALA A 733
ASN A 731
 None
 1.13A 1eqbB-3un9A:
undetectable		 1eqbB-3un9A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 12 LEU A 921
VAL A 929
SER A 734
ALA A 733
ASN A 731
 None
 1.14A 1eqbC-3un9A:
undetectable		 1eqbC-3un9A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 12 LEU A 921
VAL A 929
SER A 734
ALA A 733
ASN A 731
 None
 1.13A 1eqbD-3un9A:
undetectable		 1eqbD-3un9A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		4 / 4 THR A 744
LEU A 745
VAL A 748
LEU A 727
 None
 0.87A 1fbmD-3un9A:
undetectable		 1fbmD-3un9A:
7.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 11 LEU A 770
LYS A 768
PRO A 790
LEU A 762
PRO A 764
 None
 1.25A 1klmA-3un9A:
undetectable		 1klmA-3un9A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLS_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 12 LEU A 875
LEU A 819
GLY A 820
VAL A 842
ALA A 843
 None
 0.98A 1tlsA-3un9A:
undetectable		 1tlsA-3un9A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		3 / 3 ASP A 821
ASP A 849
ASN A 845
 None
 0.85A 2bm9D-3un9A:
undetectable		 2bm9D-3un9A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 10 ALA A 847
LEU A 883
LEU A 870
ALA A 856
VAL A 842
 None
 1.25A 2bxeA-3un9A:
2.8		 2bxeA-3un9A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_A_SAMA1300_0
(UPF0088 PROTEIN
AQ_165)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 12 LEU A 703
ASN A 731
VAL A 706
GLY A 705
LEU A 701
 None
 0.91A 2egvA-3un9A:
undetectable		 2egvA-3un9A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_B_SAMB1400_0
(UPF0088 PROTEIN
AQ_165)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 12 LEU A 703
ASN A 731
VAL A 706
GLY A 705
LEU A 701
 None
 0.91A 2egvB-3un9A:
undetectable		 2egvB-3un9A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 12 LEU A 840
ASN A 841
VAL A 796
MET A 800
LEU A 819
 None
 1.25A 2q7kA-3un9A:
undetectable		 2q7kA-3un9A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 11 LEU A 773
LEU A 770
LEU A 762
ILE A 781
THR A 817
 None
 1.22A 2qd3A-3un9A:
undetectable		 2qd3A-3un9A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		3 / 3 PRO A 671
LEU A 675
GLN A 668
 None
 0.54A 3hznG-3un9A:
undetectable
3hznH-3un9A:
undetectable		 3hznG-3un9A:
20.58
3hznH-3un9A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		4 / 8 HIS A 869
LEU A 936
LEU A 914
SER A 907
 None
 1.03A 3lm8B-3un9A:
undetectable
3lm8D-3un9A:
2.6		 3lm8B-3un9A:
20.63
3lm8D-3un9A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		6 / 12 GLY A 823
GLY A 820
ALA A 794
ALA A 797
LEU A 855
LEU A 826
 None
 1.35A 3mteB-3un9A:
undetectable		 3mteB-3un9A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		6 / 12 GLY A 823
GLY A 820
ALA A 794
ALA A 797
LEU A 855
LEU A 826
 None
 1.31A 3p2kC-3un9A:
undetectable		 3p2kC-3un9A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		6 / 12 GLY A 823
GLY A 820
ALA A 794
ALA A 797
LEU A 855
LEU A 826
 None
 1.37A 3p2kD-3un9A:
undetectable		 3p2kD-3un9A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 11 ARG A 833
LEU A 799
LEU A 826
GLY A 805
ALA A 804
 None
 1.18A 3pghB-3un9A:
undetectable		 3pghB-3un9A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		4 / 6 GLU A 960
GLY A 961
LEU A 937
GLU A 968
 None
 0.87A 3w9tB-3un9A:
undetectable		 3w9tB-3un9A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		4 / 6 GLU A 960
GLY A 961
LEU A 937
GLU A 968
 None
 0.86A 3w9tE-3un9A:
undetectable		 3w9tE-3un9A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		4 / 6 GLU A 960
GLY A 961
LEU A 937
GLU A 968
 None
 0.86A 3w9tF-3un9A:
undetectable		 3w9tF-3un9A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 11 GLY A 823
ASP A 821
ALA A 847
GLY A 820
VAL A 842
 None
 1.11A 4c5lA-3un9A:
undetectable		 4c5lA-3un9A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 9 GLY A 823
ASP A 821
ALA A 847
GLY A 820
VAL A 842
 None
 1.16A 4c5lB-3un9A:
undetectable		 4c5lB-3un9A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_C_UEGC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 10 GLY A 823
ASP A 821
ALA A 847
GLY A 820
VAL A 842
 None
 1.11A 4c5lC-3un9A:
2.2		 4c5lC-3un9A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 10 GLY A 823
ASP A 821
ALA A 847
GLY A 820
VAL A 842
 None
 1.14A 4c5lD-3un9A:
2.3		 4c5lD-3un9A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 10 GLY A 823
ASP A 821
ALA A 847
GLY A 820
VAL A 842
 None
 1.13A 4c5nB-3un9A:
3.2		 4c5nB-3un9A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		4 / 8 GLY A 823
ASP A 821
GLY A 820
VAL A 842
 None
 0.89A 4c5nC-3un9A:
2.6		 4c5nC-3un9A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 10 GLY A 823
ASP A 821
ALA A 847
GLY A 820
VAL A 842
 None
 1.16A 4c5nD-3un9A:
2.5		 4c5nD-3un9A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		4 / 7 VAL A 959
VAL A 963
LEU A 966
VAL A 929
 None
 0.98A 4e1gB-3un9A:
undetectable		 4e1gB-3un9A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 12 LEU A 773
LEU A 770
LEU A 762
ILE A 781
THR A 817
 None
 1.25A 4f4dA-3un9A:
undetectable		 4f4dA-3un9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		4 / 7 ASN A 806
LEU A 803
LEU A 799
LEU A 812
 None
 0.75A 4wg0L-3un9A:
undetectable
4wg0M-3un9A:
undetectable		 4wg0L-3un9A:
7.53
4wg0M-3un9A:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE0_A_XINA401_2
(AP2-ASSOCIATED
PROTEIN KINASE 1)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		4 / 5 LEU A 701
VAL A 730
CYH A 713
CYH A 735
 None
 1.40A 5te0A-3un9A:
undetectable		 5te0A-3un9A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 12 LEU A 745
LEU A 746
ILE A 781
LEU A 773
LEU A 727
 None
 1.18A 5toaB-3un9A:
undetectable		 5toaB-3un9A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		3 / 3 ARG A 860
ARG A 895
ARG A 884
 None
 0.75A 5vcgA-3un9A:
undetectable		 5vcgA-3un9A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FTP_B_DM2B501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3un9 NLR FAMILY MEMBER X1
(Homo
sapiens) 		5 / 9 GLN A 969
LEU A 914
SER A 915
LEU A 921
ASN A 702
 None
 1.50A 6ftpA-3un9A:
undetectable
6ftpB-3un9A:
undetectable		 6ftpA-3un9A:
11.56
6ftpB-3un9A:
6.56