SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3unv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 3unv ADMH
(Pantoea
agglomerans) 		3 / 3 ALA A 175
VAL A 180
TRP A 185
 None
 0.79A 1bdwA-3unvA:
undetectable
1bdwB-3unvA:
undetectable		 1bdwA-3unvA:
6.47
1bdwB-3unvA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 3unv ADMH
(Pantoea
agglomerans) 		5 / 12 PHE A 480
LEU A 476
ALA A 392
THR A 325
LEU A 244
 None
 1.04A 1cbsA-3unvA:
undetectable		 1cbsA-3unvA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3unv ADMH
(Pantoea
agglomerans) 		4 / 4 THR A 325
LEU A 329
VAL A 332
LEU A 336
 None
 1.03A 1fbmB-3unvA:
undetectable		 1fbmB-3unvA:
5.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 3unv ADMH
(Pantoea
agglomerans) 		4 / 7 VAL A 277
ILE A 281
GLU A 483
LEU A 506
 None
 0.89A 1j96B-3unvA:
undetectable		 1j96B-3unvA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 3unv ADMH
(Pantoea
agglomerans) 		5 / 11 GLU A 276
GLY A 273
ARG A 395
LEU A 391
LEU A 244
 None
 1.20A 1mjqA-3unvA:
undetectable
1mjqB-3unvA:
undetectable		 1mjqA-3unvA:
12.39
1mjqB-3unvA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3unv ADMH
(Pantoea
agglomerans) 		5 / 12 PHE A  27
SER A  26
LEU A  52
VAL A  56
VAL A  50
 None
 1.39A 1q23C-3unvA:
undetectable		 1q23C-3unvA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3unv ADMH
(Pantoea
agglomerans) 		5 / 12 LEU A 391
LEU A 385
ALA A 384
LEU A 336
LEU A 244
 None
 1.09A 1s9pB-3unvA:
undetectable		 1s9pB-3unvA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 3unv ADMH
(Pantoea
agglomerans) 		4 / 6 ALA A 217
LEU A 216
ILE A 219
CYH A 181
 None
 1.07A 1sbrA-3unvA:
undetectable
1sbrB-3unvA:
undetectable		 1sbrA-3unvA:
16.76
1sbrB-3unvA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 3unv ADMH
(Pantoea
agglomerans) 		3 / 3 ALA A 178
VAL A 180
TRP A 185
 None
 0.96A 1w5uA-3unvA:
undetectable
1w5uB-3unvA:
undetectable		 1w5uA-3unvA:
6.47
1w5uB-3unvA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 3unv ADMH
(Pantoea
agglomerans) 		3 / 3 TRP A 185
ALA A 178
VAL A 180
 None
 0.93A 2izqC-3unvA:
undetectable
2izqD-3unvA:
undetectable		 2izqC-3unvA:
6.47
2izqD-3unvA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 3unv ADMH
(Pantoea
agglomerans) 		4 / 5 LEU A  37
ALA A  41
LEU A 231
MET A 378
 None
 0.68A 2oaxA-3unvA:
undetectable		 2oaxA-3unvA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3unv ADMH
(Pantoea
agglomerans) 		4 / 7 ILE A 322
GLY A 256
LEU A 290
PHE A 399
 None
 1.03A 2vctD-3unvA:
3.1		 2vctD-3unvA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)		 3unv ADMH
(Pantoea
agglomerans) 		5 / 12 THR A 430
ILE A 527
ASN A 390
THR A 510
LEU A 535
 None
 1.27A 3a50E-3unvA:
2.4		 3a50E-3unvA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_C_TOPC200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3unv ADMH
(Pantoea
agglomerans) 		5 / 11 ALA A 487
LEU A 506
VAL A 246
ILE A 530
LEU A 535
 None
 1.29A 3fl9C-3unvA:
undetectable		 3fl9C-3unvA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_H_TOPH200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3unv ADMH
(Pantoea
agglomerans) 		5 / 9 ALA A 487
LEU A 506
VAL A 246
ILE A 530
LEU A 535
 None
 1.34A 3fl9H-3unvA:
undetectable		 3fl9H-3unvA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3unv ADMH
(Pantoea
agglomerans) 		4 / 7 VAL A 514
ILE A 523
TYR A 526
ILE A 527
 None
 1.03A 3hgxA-3unvA:
2.6		 3hgxA-3unvA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3unv ADMH
(Pantoea
agglomerans) 		3 / 3 ALA A 466
ARG A 470
LYS A 474
 None
 0.91A 3kp3B-3unvA:
0.8		 3kp3B-3unvA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_B_KANB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3unv ADMH
(Pantoea
agglomerans) 		3 / 3 ALA A 466
ARG A 470
LYS A 474
 None
 0.76A 3kp5B-3unvA:
0.8		 3kp5B-3unvA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 3unv ADMH
(Pantoea
agglomerans) 		4 / 7 LEU A 408
VAL A 246
LEU A 249
SER A 250
 None
 0.70A 3r9vA-3unvA:
1.4
3r9vB-3unvA:
2.0		 3r9vA-3unvA:
21.78
3r9vB-3unvA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CUT_A_TYLA2971_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 3unv ADMH
(Pantoea
agglomerans) 		4 / 4 VAL A 230
VAL A 226
ASN A 348
ILE A  35
 None
 1.32A 4cutA-3unvA:
1.1		 4cutA-3unvA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3unv ADMH
(Pantoea
agglomerans) 		4 / 8 LEU A 174
SER A 460
VAL A 230
GLY A 229
 None
KWS  A 168 ( 4.5A)
None
None
 0.86A 4klrB-3unvA:
undetectable		 4klrB-3unvA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 3unv ADMH
(Pantoea
agglomerans) 		5 / 12 LEU A 347
LEU A  52
GLU A  39
ILE A  40
ALA A  43
 None
 0.99A 4ltwA-3unvA:
undetectable		 4ltwA-3unvA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3unv ADMH
(Pantoea
agglomerans) 		5 / 12 LEU A 174
LEU A 147
MET A 225
ALA A 127
SER A 131
 None
 1.19A 4m11A-3unvA:
0.3		 4m11A-3unvA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 3unv ADMH
(Pantoea
agglomerans) 		4 / 5 ASN A 143
LEU A 218
LEU A 179
ASN A 106
 None
 1.21A 4n09C-3unvA:
undetectable		 4n09C-3unvA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 3unv ADMH
(Pantoea
agglomerans) 		5 / 12 CYH A 486
LEU A 412
ALA A 490
LEU A 254
ILE A 396
 None
 1.12A 5eypB-3unvA:
undetectable		 5eypB-3unvA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3unv ADMH
(Pantoea
agglomerans) 		5 / 10 GLY A 498
GLY A 495
LEU A 290
LEU A 249
TYR A 507
 None
EDO  A1007 (-3.1A)
None
None
None
 1.35A 5hwkA-3unvA:
undetectable		 5hwkA-3unvA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3unv ADMH
(Pantoea
agglomerans) 		5 / 10 GLY A 498
GLY A 495
LEU A 290
LEU A 249
TYR A 507
 None
EDO  A1007 (-3.1A)
None
None
None
 1.36A 5hwkB-3unvA:
undetectable		 5hwkB-3unvA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3unv ADMH
(Pantoea
agglomerans) 		4 / 6 ASP A 379
ASN A 390
ASN A 382
GLN A 472
 None
 0.97A 5l6eA-3unvA:
undetectable		 5l6eA-3unvA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_2
(TUBULIN BETA-2B
CHAIN)		 3unv ADMH
(Pantoea
agglomerans) 		5 / 12 CYH A 486
LEU A 412
ALA A 490
LEU A 254
ILE A 396
 None
 1.06A 5nm5B-3unvA:
undetectable		 5nm5B-3unvA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_0
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 3unv ADMH
(Pantoea
agglomerans) 		5 / 12 SER A 500
LEU A 499
GLN A 489
VAL A 491
LEU A 290
 None
 1.30A 5ubbA-3unvA:
undetectable		 5ubbA-3unvA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3unv ADMH
(Pantoea
agglomerans) 		4 / 8 VAL A 156
HIS A  47
GLY A 227
LEU A 231
 None
 0.83A 5w3jB-3unvA:
undetectable		 5w3jB-3unvA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA609_0
(ALPHA-AMYLASE)		 3unv ADMH
(Pantoea
agglomerans) 		4 / 7 LYS A 170
GLY A 166
ASP A 379
MET A 378
 KWS  A 168 ( 3.3A)
KWS  A 168 ( 2.5A)
None
None
 1.37A 6ag0A-3unvA:
undetectable		 6ag0A-3unvA:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC609_0
(ALPHA-AMYLASE)		 3unv ADMH
(Pantoea
agglomerans) 		4 / 7 LYS A 170
GLY A 166
ASP A 379
MET A 378
 KWS  A 168 ( 3.3A)
KWS  A 168 ( 2.5A)
None
None
 1.36A 6ag0C-3unvA:
undetectable		 6ag0C-3unvA:
10.15