SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uo2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3uo2 J-TYPE CO-CHAPERONE
JAC1, MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		3 / 3 THR A  68
ASP A  87
SER A  94
 None
 0.78A 2nxeA-3uo2A:
undetectable		 2nxeA-3uo2A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3uo2 J-TYPE CO-CHAPERONE
JAC1, MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		3 / 3 THR A  68
ASP A  87
SER A  94
 None
 0.83A 2nxeB-3uo2A:
undetectable		 2nxeB-3uo2A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 3uo2 J-TYPE CO-CHAPERONE
JAC1, MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 127
GLN A 117
LEU A 115
GLU A 114
 None
 0.96A 3h5gA-3uo2A:
undetectable
3h5gB-3uo2A:
undetectable		 3h5gA-3uo2A:
11.43
3h5gB-3uo2A:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 3uo2 J-TYPE CO-CHAPERONE
JAC1, MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 127
GLN A 117
LEU A 115
GLU A 114
 None
 1.11A 3h5gB-3uo2A:
undetectable
3h5gC-3uo2A:
undetectable		 3h5gB-3uo2A:
11.43
3h5gC-3uo2A:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 3uo2 J-TYPE CO-CHAPERONE
JAC1, MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 147
PRO A  27
LEU A  69
PHE A  22
ILE A  31
 None
 1.40A 5dv4A-3uo2A:
undetectable		 5dv4A-3uo2A:
18.55