SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uo7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3uo7 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		5 / 10 LEU A 132
THR A 264
ILE A 259
PHE A 189
ILE A 137
 None
 1.27A 1i18A-3uo7A:
undetectable
1i18B-3uo7A:
undetectable		 1i18A-3uo7A:
17.50
1i18B-3uo7A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3uo7 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		5 / 10 PHE A 189
ILE A 137
LEU A 132
THR A 264
ILE A 259
 None
 1.26A 1i18A-3uo7A:
undetectable
1i18B-3uo7A:
undetectable		 1i18A-3uo7A:
17.50
1i18B-3uo7A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 3uo7 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		4 / 6 LEU A 292
ILE A 187
ARG A 225
ILE A 226
 None
 0.83A 2q8hA-3uo7A:
undetectable		 2q8hA-3uo7A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3uo7 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		5 / 12 VAL A 247
ILE A 237
ILE A 137
MET A 192
VAL A 135
 None
 1.42A 3g8iA-3uo7A:
undetectable		 3g8iA-3uo7A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3uo7 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		3 / 3 ASP A 202
ARG A 275
LYS A 201
 None
 0.97A 3wipG-3uo7A:
undetectable		 3wipG-3uo7A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 3uo7 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		3 / 3 HIS A 150
ASP A 178
HIS A 179
 None
 0.74A 5oexA-3uo7A:
undetectable		 5oexA-3uo7A:
16.00