SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uof'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3uof BACTERIOFERRITIN
(Mycobacterium
tuberculosis) 		3 / 3 THR A 115
GLU A  57
ASP A  50
 None
 0.70A 1nt2A-3uofA:
undetectable		 1nt2A-3uofA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_2
(BETA-LACTAMASE
CTX-M-9)		 3uof BACTERIOFERRITIN
(Mycobacterium
tuberculosis) 		4 / 5 CYH A 108
PRO A   5
THR A 114
SER A 116
 None
 1.32A 1ymxA-3uofA:
undetectable		 1ymxA-3uofA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3uof BACTERIOFERRITIN
(Mycobacterium
tuberculosis) 		4 / 5 SER A 155
HIS A  43
ASP A  90
ASP A  33
 None
 1.13A 2oxtB-3uofA:
undetectable		 2oxtB-3uofA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3uof BACTERIOFERRITIN
(Mycobacterium
tuberculosis) 		5 / 12 GLN A   2
ASP A 113
THR A 115
LEU A  11
GLY A  67
 None
 1.33A 3g1uB-3uofA:
undetectable		 3g1uB-3uofA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 3uof BACTERIOFERRITIN
(Mycobacterium
tuberculosis) 		4 / 7 PRO A  69
GLY A  67
ASP A  60
ARG A  61
 None
 0.77A 3ur0B-3uofA:
undetectable		 3ur0B-3uofA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_A_ASCA1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3uof BACTERIOFERRITIN
(Mycobacterium
tuberculosis) 		4 / 6 HIS A  28
TYR A 133
GLN A  32
HIS A  43
 None
 1.42A 5kkzA-3uofA:
1.9
5kkzG-3uofA:
undetectable		 5kkzA-3uofA:
15.53
5kkzG-3uofA:
21.88