SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uog'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 3uog ALCOHOL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 6 LEU A 152
ALA A  93
SER A  66
THR A 112
 None
 0.93A 1ictB-3uogA:
undetectable		 1ictB-3uogA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3uog ALCOHOL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 5 GLY A 119
SER A   9
THR A  10
PHE A  62
 None
 1.20A 1icvC-3uogA:
undetectable
1icvD-3uogA:
undetectable		 1icvC-3uogA:
21.98
1icvD-3uogA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)		 3uog ALCOHOL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		6 / 10 ALA A 186
ALA A 188
LEU A 306
ALA A 302
LEU A 164
VAL A 159
 None
 1.37A 2bxgB-3uogA:
undetectable		 2bxgB-3uogA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 3uog ALCOHOL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 6 LEU A 152
ALA A  93
SER A  66
THR A 112
 None
 0.99A 3cfqA-3uogA:
undetectable		 3cfqA-3uogA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 3uog ALCOHOL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		3 / 3 GLU A 320
GLU A 323
TRP A   8
 None
 1.02A 3hrdA-3uogA:
undetectable
3hrdE-3uogA:
undetectable
3hrdF-3uogA:
undetectable		 3hrdA-3uogA:
23.34
3hrdE-3uogA:
23.34
3hrdF-3uogA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3uog ALCOHOL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 ASN A  43
VAL A 178
ALA A 179
ILE A 241
ARG A 330
 None
 1.14A 3n23A-3uogA:
5.3		 3n23A-3uogA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 3uog ALCOHOL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 GLY A  53
ASP A  57
LEU A  58
GLU A  51
VAL A  13
 None
 0.89A 3o7wA-3uogA:
3.9		 3o7wA-3uogA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3uog ALCOHOL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A 306
GLY A 182
LEU A 299
ALA A 157
TRP A 155
 None
 1.13A 3ou6A-3uogA:
4.8		 3ou6A-3uogA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3uog ALCOHOL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A 306
GLY A 182
LEU A 299
ALA A 157
TRP A 155
 None
 1.12A 3ou6B-3uogA:
4.9		 3ou6B-3uogA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3uog ALCOHOL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A 306
GLY A 182
LEU A 299
ALA A 157
TRP A 155
 None
 1.09A 3ou7B-3uogA:
4.8		 3ou7B-3uogA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3uog ALCOHOL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 5 LEU A 158
GLY A 182
ILE A 194
VAL A 195
 None
 0.86A 3wriA-3uogA:
undetectable		 3wriA-3uogA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 3uog ALCOHOL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 5 LEU A 158
GLY A 182
ILE A 194
VAL A 195
 None
 0.85A 3wriB-3uogA:
undetectable		 3wriB-3uogA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_B_MTXB603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3uog ALCOHOL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 ALA A 206
LEU A 180
SER A 198
ILE A 241
ARG A 217
 None
None
SO4  A 501 (-3.3A)
None
SO4  A 501 (-3.4A)
 1.11A 4ky8B-3uogA:
undetectable		 4ky8B-3uogA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3uog ALCOHOL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 7 GLU A 123
GLU A   7
GLU A  22
ARG A  23
 None
 1.05A 4mi4B-3uogA:
undetectable
4mi4C-3uogA:
undetectable		 4mi4B-3uogA:
24.39
4mi4C-3uogA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3uog ALCOHOL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 8 GLU A 123
GLU A   7
GLU A  22
ARG A  23
 None
 1.02A 4mj8B-3uogA:
undetectable
4mj8C-3uogA:
undetectable		 4mj8B-3uogA:
19.71
4mj8C-3uogA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 3uog ALCOHOL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 9 ASP A  46
ALA A  14
GLY A 114
PHE A  62
GLY A  53
 None
 1.38A 4mmeA-3uogA:
undetectable		 4mmeA-3uogA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 3uog ALCOHOL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 9 ASP A  46
ALA A  14
GLY A 114
PHE A  62
GLY A  53
 None
 1.37A 4mmfA-3uogA:
undetectable		 4mmfA-3uogA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3uog ALCOHOL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		3 / 3 THR A  10
HIS A 327
LEU A  42
 None
 0.80A 5axdA-3uogA:
2.4		 5axdA-3uogA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 3uog ALCOHOL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 4 LEU A 121
ILE A 338
PRO A 322
LEU A 325
 None
 1.17A 5eb3A-3uogA:
3.4		 5eb3A-3uogA:
17.75