SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uon'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IOL_A_ESTA400_1 (ESTROGENIC 17-BETA HYDROXYSTEROID DEHYDROGENASE)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	5 / 11	GLY A1028 LEU A1013 TYR A1018 PHE A1067 GLU A1005	None	1.42A	1iolA-3uonA: undetectable	1iolA-3uonA: 19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WX2_A_TPFA1460_1 (LANOSTEROL 14-ALPHA-DEMETHYLASE)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	4 / 7	TYR A 440 ALA A 391 ALA A 395 THR A 399	None	0.90A	2wx2A-3uonA: undetectable	2wx2A-3uonA: 22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WX2_B_TPFB1460_1 (LANOSTEROL 14-ALPHA-DEMETHYLASE)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	4 / 8	TYR A 440 ALA A 391 ALA A 395 THR A 399	None	0.95A	2wx2B-3uonA: undetectable	2wx2B-3uonA: 22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KHM_A_TPFA501_1 (STEROL 14 ALPHA-DEMETHYLASE)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	4 / 8	TYR A 440 ALA A 391 ALA A 395 THR A 399	None	0.92A	3khmA-3uonA: 2.2	3khmA-3uonA: 22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L4D_A_TPFA490_1 (STEROL 14-ALPHA DEMETHYLASE)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	4 / 8	TYR A 440 ALA A 391 ALA A 395 THR A 399	None	0.81A	3l4dA-3uonA: undetectable	3l4dA-3uonA: 21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L4D_D_TPFD490_1 (STEROL 14-ALPHA DEMETHYLASE)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	4 / 8	TYR A 440 ALA A 391 ALA A 395 THR A 399	None	0.88A	3l4dD-3uonA: undetectable	3l4dD-3uonA: 21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LCV_B_SAMB301_1 (SISOMICIN-GENTAMICIN RESISTANCE METHYLASE SGM)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Homo sapiens; Escherichia virus T4)	3 / 3	ARG A 121 ASP A1061 GLN A1069	None	0.95A	3lcvB-3uonA: undetectable	3lcvB-3uonA: 20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3M0W_E_P77E203_1 (PROTEIN S100-A4)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	4 / 8	ASP A 103 SER A 107 SER A 433 LEU A 33	QNB A1162 (-3.1A) QNB A1162 (-3.4A) None None	1.04A	3m0wE-3uonA: undetectable 3m0wF-3uonA: undetectable 3m0wG-3uonA: undetectable 3m0wH-3uonA: undetectable	3m0wE-3uonA: 12.97 3m0wF-3uonA: 12.97 3m0wG-3uonA: 12.97 3m0wH-3uonA: 12.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3RZE_A_D7VA1201_1 (HISTAMINE H1 RECEPTOR, LYSOZYME CHIMERA)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 TRP A 400	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.7A)	1.13A	3rzeA-3uonA: 34.4	3rzeA-3uonA: 58.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3RZE_A_D7VA1201_1 (HISTAMINE H1 RECEPTOR, LYSOZYME CHIMERA)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 TYR A 403 TYR A 430	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-3.9A) QNB A1162 ( 4.8A)	0.79A	3rzeA-3uonA: 34.4	3rzeA-3uonA: 58.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TPX_E_ACTE204_0 (E3 UBIQUITIN-PROTEIN LIGASE MDM2)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Homo sapiens; Escherichia virus T4)	3 / 3	LYS A 127 PRO A 128 LEU A 129	None	0.56A	3tpxE-3uonA: undetectable	3tpxE-3uonA: 11.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 103 TYR A 104 ALA A 191 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	1.49A	4dajA-3uonA: 39.6	4dajA-3uonA: 73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 103 TYR A 104 SER A 107 ASN A 108 TRP A 155 THR A 187 ALA A 194 TRP A 400 TYR A 403 ASN A 404 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.9A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	0.59A	4dajA-3uonA: 39.6	4dajA-3uonA: 73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 THR A 187 ALA A 194 TRP A 400 TYR A 403 ASN A 404 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.74A	4dajA-3uonA: 39.6	4dajA-3uonA: 73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	6 / 12	ASP A 103 TYR A 104 THR A 190 TRP A 400 ASN A 404 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-4.3A) QNB A1162 (-4.7A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	1.45A	4dajA-3uonA: 39.6	4dajA-3uonA: 73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 103 TYR A 104 ALA A 191 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	1.40A	4dajB-3uonA: 39.8	4dajB-3uonA: 73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	12 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 THR A 187 THR A 190 ALA A 194 TRP A 400 TYR A 403 ASN A 404 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.75A	4dajB-3uonA: 39.8	4dajB-3uonA: 73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 103 TYR A 104 THR A 187 ALA A 191 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-4.8A) QNB A1162 (-3.9A) QNB A1162 ( 4.0A)	1.29A	4dajB-3uonA: 39.8	4dajB-3uonA: 73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	6 / 12	ASP A 103 TYR A 104 THR A 190 TRP A 400 ASN A 404 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-4.3A) QNB A1162 (-4.7A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	1.43A	4dajB-3uonA: 39.8	4dajB-3uonA: 73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 103 TYR A 104 SER A 107 ASN A 108 TRP A 155 THR A 187 THR A 190 TRP A 400 TYR A 403 ASN A 404 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.9A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	0.75A	4dajC-3uonA: 39.6	4dajC-3uonA: 73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 THR A 187 THR A 190 TRP A 400 TYR A 403 ASN A 404 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.85A	4dajC-3uonA: 39.6	4dajC-3uonA: 73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 103 TYR A 104 SER A 107 ASN A 108 TRP A 155 THR A 187 THR A 190 TRP A 400 TYR A 403 ASN A 404 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.9A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	0.62A	4dajD-3uonA: 39.6	4dajD-3uonA: 73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 THR A 187 THR A 190 TRP A 400 TYR A 403 ASN A 404 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.76A	4dajD-3uonA: 39.6	4dajD-3uonA: 73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	6 / 12	ASP A 103 TYR A 104 THR A 190 TRP A 400 ASN A 404 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-4.3A) QNB A1162 (-4.7A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	1.48A	4dajD-3uonA: 39.6	4dajD-3uonA: 73.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NC3_A_ERMA1202_1 (CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 2B AND E. COLI SOLUBLE CYTOCHROME B562)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	6 / 12	LEU A 100 ASP A 103 SER A 107 PHE A 181 ALA A 194 TRP A 400	None QNB A1162 (-3.1A) QNB A1162 (-3.4A) QNB A1162 (-4.4A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A)	1.24A	4nc3A-3uonA: 27.0	4nc3A-3uonA: 28.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P7N_A_GCSA702_1 (POLY-BETA-1,6-N-ACET YL-D-GLUCOSAMINE N-DEACETYLASE)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	3 / 3	ASP A 103 TYR A 104 TRP A 99	QNB A1162 (-3.1A) QNB A1162 (-4.0A) None	1.38A	4p7nA-3uonA: undetectable	4p7nA-3uonA: 21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_C_377C401_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	4 / 6	TYR A 403 ASN A 404 TYR A 104 PHE A 181	QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 (-4.0A) QNB A1162 (-4.4A)	1.26A	4twdB-3uonA: 2.7 4twdC-3uonA: 2.7	4twdB-3uonA: 19.33 4twdC-3uonA: 19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_C_377C402_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	4 / 5	TYR A 403 ASN A 404 TYR A 104 PHE A 181	QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 (-4.0A) QNB A1162 (-4.4A)	1.31A	4twdC-3uonA: 2.7 4twdD-3uonA: 2.8	4twdC-3uonA: 19.33 4twdD-3uonA: 19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_H_377H401_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	4 / 6	TYR A 403 ASN A 404 TYR A 104 PHE A 181	QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 (-4.0A) QNB A1162 (-4.4A)	1.32A	4twdG-3uonA: undetectable 4twdH-3uonA: 1.7	4twdG-3uonA: 19.33 4twdH-3uonA: 19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_J_377J401_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	4 / 6	TYR A 403 ASN A 404 TYR A 104 PHE A 181	QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 (-4.0A) QNB A1162 (-4.4A)	1.31A	4twdI-3uonA: undetectable 4twdJ-3uonA: undetectable	4twdI-3uonA: 19.33 4twdJ-3uonA: 19.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 103 TYR A 104 ALA A 191 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	1.49A	4u14A-3uonA: 38.6	4u14A-3uonA: 73.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	12 / 12	ILE A 72 ASP A 103 TYR A 104 SER A 107 TRP A 155 THR A 187 ALA A 191 ALA A 194 TRP A 400 ASN A 404 TYR A 426 CYH A 429	None QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 (-3.9A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 (-2.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.91A	4u14A-3uonA: 38.6	4u14A-3uonA: 73.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	7 / 12	ILE A 72 ASP A 103 TYR A 104 THR A 190 TRP A 400 ASN A 404 CYH A 429	None QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-4.3A) QNB A1162 (-4.7A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	1.43A	4u14A-3uonA: 38.6	4u14A-3uonA: 73.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	6 / 12	ILE A 72 TYR A 104 THR A 190 ALA A 194 TRP A 400 CYH A 429	None QNB A1162 (-4.0A) QNB A1162 (-4.3A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 ( 4.0A)	1.49A	4u14A-3uonA: 38.6	4u14A-3uonA: 73.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	12 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 THR A 187 THR A 190 ALA A 191 ALA A 194 TRP A 400 ASN A 404 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 (-3.9A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 (-2.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.79A	4u15A-3uonA: 39.0	4u15A-3uonA: 65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 103 TYR A 104 THR A 187 ALA A 191 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-4.8A) QNB A1162 (-3.9A) QNB A1162 ( 4.0A)	1.23A	4u15A-3uonA: 39.0	4u15A-3uonA: 65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	6 / 12	ASP A 103 TYR A 104 THR A 190 TRP A 400 ASN A 404 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-4.3A) QNB A1162 (-4.7A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	1.43A	4u15A-3uonA: 39.0	4u15A-3uonA: 65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	6 / 12	TYR A 104 SER A 107 TRP A 155 TRP A 400 TYR A 403 CYH A 429	QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 ( 4.0A)	1.47A	4u15A-3uonA: 39.0	4u15A-3uonA: 65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	3 / 3	ASN A 108 PHE A 195 TYR A 403	QNB A1162 (-4.9A) QNB A1162 (-4.4A) QNB A1162 (-3.9A)	0.53A	4u15A-3uonA: 39.0	4u15A-3uonA: 65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 103 TYR A 104 SER A 107 THR A 187 THR A 190 ALA A 191 ALA A 194 TRP A 400 TYR A 403 ASN A 404 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 (-3.9A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	0.52A	4u15B-3uonA: 19.2	4u15B-3uonA: 65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 103 TYR A 104 THR A 187 ALA A 191 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-4.8A) QNB A1162 (-3.9A) QNB A1162 ( 4.0A)	1.25A	4u15B-3uonA: 19.2	4u15B-3uonA: 65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	TYR A 104 SER A 107 THR A 187 THR A 190 ALA A 191 ALA A 194 TRP A 400 TYR A 403 ASN A 404 TYR A 426 CYH A 429	QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 (-3.9A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.73A	4u15B-3uonA: 19.2	4u15B-3uonA: 65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 103 TYR A 104 ALA A 191 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	1.40A	5cxvA-3uonA: 39.7	5cxvA-3uonA: 68.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 ALA A 191 ALA A 194 TRP A 400 TYR A 403 ASN A 404 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-3.9A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.74A	5cxvA-3uonA: 39.7	5cxvA-3uonA: 68.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	3 / 3	THR A 187 THR A 190 PHE A 195	QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 (-4.4A)	0.51A	5cxvA-3uonA: 39.7	5cxvA-3uonA: 68.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 THR A 187 TRP A 400 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.8A) QNB A1162 (-4.7A) QNB A1162 ( 4.0A)	1.39A	5dsgA-3uonA: 39.7	5dsgA-3uonA: 76.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	10 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 THR A 187 THR A 190 TRP A 400 TYR A 403 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.91A	5dsgA-3uonA: 39.7	5dsgA-3uonA: 76.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 103 TYR A 104 THR A 187 ALA A 191 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-4.8A) QNB A1162 (-3.9A) QNB A1162 ( 4.0A)	1.37A	5dsgA-3uonA: 39.7	5dsgA-3uonA: 76.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	6 / 12	TYR A 104 SER A 107 THR A 187 TRP A 400 ASN A 404 CYH A 429	QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.8A) QNB A1162 (-4.7A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	1.47A	5dsgA-3uonA: 39.7	5dsgA-3uonA: 76.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	TYR A 104 SER A 107 TRP A 155 THR A 187 THR A 190 ALA A 194 TRP A 400 TYR A 403 ASN A 404 TYR A 426 CYH A 429	QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.75A	5dsgA-3uonA: 39.7	5dsgA-3uonA: 76.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	6 / 12	TYR A 104 SER A 107 THR A 187 TRP A 400 ASN A 404 CYH A 429	QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.8A) QNB A1162 (-4.7A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	1.48A	5dsgB-3uonA: 38.3	5dsgB-3uonA: 76.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	TYR A 104 SER A 107 TRP A 155 THR A 187 THR A 190 ALA A 194 TRP A 400 TYR A 403 ASN A 404 TYR A 426 CYH A 429	QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.73A	5dsgB-3uonA: 38.3	5dsgB-3uonA: 76.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW8_A_FK5A201_1 (FK506-BINDING PROTEIN 1)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	5 / 11	VAL A 95 TRP A 89 ILE A 178 ILE A 71 ILE A 72	None	1.07A	5hw8A-3uonA: undetectable 5hw8D-3uonA: undetectable	5hw8A-3uonA: 12.69 5hw8D-3uonA: 12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5V_A_ECLA1001_1 (TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	4 / 7	ILE A 48 LEU A 54 ILE A 392 ALA A 445	None	0.83A	6b5vA-3uonA: 1.2 6b5vC-3uonA: 0.0	6b5vA-3uonA: 15.12 6b5vC-3uonA: 15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5V_C_ECLC1001_1 (TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	4 / 7	ILE A 48 LEU A 54 ILE A 392 ALA A 445	None	0.83A	6b5vC-3uonA: 0.0 6b5vD-3uonA: undetectable	6b5vC-3uonA: 15.12 6b5vD-3uonA: 15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5V_D_ECLD1001_1 (TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	4 / 7	ALA A 445 ILE A 48 LEU A 54 ILE A 392	None	0.83A	6b5vB-3uonA: undetectable 6b5vD-3uonA: undetectable	6b5vB-3uonA: 15.12 6b5vD-3uonA: 15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CDU_G_EY4G501_0 (CHIMERIC ALPHA1GABAA RECEPTOR)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Homo sapiens; Escherichia virus T4)	4 / 7	ILE A 398 PRO A 402 ILE A 435 THR A 434	None	0.94A	6cduF-3uonA: 3.7 6cduG-3uonA: 3.8	6cduF-3uonA: 22.13 6cduG-3uonA: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DRX_A_H8GA1201_0 (5HT2B RECEPTOR, BRIL CHIMERA)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Homo sapiens; Escherichia virus T4)	5 / 12	TRP A 99 LEU A 100 SER A 107 PHE A 181 ALA A 194	None None QNB A1162 (-3.4A) QNB A1162 (-4.4A) QNB A1162 ( 4.0A)	0.99A	6drxA-3uonA: 26.7	6drxA-3uonA: 27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DRX_A_H8GA1201_0 (5HT2B RECEPTOR, BRIL CHIMERA)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Homo sapiens; Escherichia virus T4)	5 / 12	TRP A 99 LEU A 100 SER A 107 PHE A 181 TRP A 400	None None QNB A1162 (-3.4A) QNB A1162 (-4.4A) QNB A1162 (-4.7A)	1.31A	6drxA-3uonA: 26.7	6drxA-3uonA: 27.97

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1IOL_A_ESTA400_1","ESTROGENIC 17-BETA HYDROXYSTEROID DEHYDROGENASE","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",5,"GLY A1028;LEU A1013;TYR A1018;PHE A1067;GLU A1005","None","1.42A","1iolA-3uonA:undetectable","1iolA-3uonA:19.96"],["2WX2_A_TPFA1460_1","LANOSTEROL 14-ALPHA-DEMETHYLASE","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",4,"TYR A 440;ALA A 391;ALA A 395;THR A 399","None","0.90A","2wx2A-3uonA:undetectable","2wx2A-3uonA:22.79"],["2WX2_B_TPFB1460_1","LANOSTEROL 14-ALPHA-DEMETHYLASE","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",4,"TYR A 440;ALA A 391;ALA A 395;THR A 399","None","0.95A","2wx2B-3uonA:undetectable","2wx2B-3uonA:22.79"],["3KHM_A_TPFA501_1","STEROL 14 ALPHA-DEMETHYLASE","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",4,"TYR A 440;ALA A 391;ALA A 395;THR A 399","None","0.92A","3khmA-3uonA:2.2","3khmA-3uonA:22.24"],["3L4D_A_TPFA490_1","STEROL 14-ALPHA DEMETHYLASE","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",4,"TYR A 440;ALA A 391;ALA A 395;THR A 399","None","0.81A","3l4dA-3uonA:undetectable","3l4dA-3uonA:21.24"],["3L4D_D_TPFD490_1","STEROL 14-ALPHA DEMETHYLASE","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",4,"TYR A 440;ALA A 391;ALA A 395;THR A 399","None","0.88A","3l4dD-3uonA:undetectable","3l4dD-3uonA:21.24"],["3LCV_B_SAMB301_1","SISOMICIN-GENTAMICIN RESISTANCE METHYLASE SGM","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Homo sapiens;Escherichia virus T4",3,"ARG A 121;ASP A1061;GLN A1069","None","0.95A","3lcvB-3uonA:undetectable","3lcvB-3uonA:20.77"],["3M0W_E_P77E203_1","PROTEIN S100-A4;PROTEIN S100-A4;PROTEIN S100-A4;PROTEIN S100-A4","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",4,"ASP A 103;SER A 107;SER A 433;LEU A  33","QNB A1162 (-3.1A);QNB A1162 (-3.4A);None;None","1.04A","3m0wE-3uonA:undetectable;3m0wF-3uonA:undetectable;3m0wG-3uonA:undetectable;3m0wH-3uonA:undetectable","3m0wE-3uonA:12.97;3m0wF-3uonA:12.97;3m0wG-3uonA:12.97;3m0wH-3uonA:12.97"],["3RZE_A_D7VA1201_1","HISTAMINE H1 RECEPTOR, LYSOZYME CHIMERA","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",5,"ASP A 103;TYR A 104;SER A 107;TRP A 155;TRP A 400","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.2A);QNB A1162 (-4.7A)","1.13A","3rzeA-3uonA:34.4","3rzeA-3uonA:58.49"],["3RZE_A_D7VA1201_1","HISTAMINE H1 RECEPTOR, LYSOZYME CHIMERA","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",6,"ASP A 103;TYR A 104;SER A 107;TRP A 155;TYR A 403;TYR A 430","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.2A);QNB A1162 (-3.9A);QNB A1162 ( 4.8A)","0.79A","3rzeA-3uonA:34.4","3rzeA-3uonA:58.49"],["3TPX_E_ACTE204_0","E3 UBIQUITIN-PROTEIN LIGASE MDM2","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Homo sapiens;Escherichia virus T4",3,"LYS A 127;PRO A 128;LEU A 129","None","0.56A","3tpxE-3uonA:undetectable","3tpxE-3uonA:11.70"],["4DAJ_A_0HKA2000_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",5,"ASP A 103;TYR A 104;ALA A 191;TYR A 426;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-3.9A);QNB A1162 ( 4.2A);QNB A1162 ( 4.0A)","1.49A","4dajA-3uonA:39.6","4dajA-3uonA:73.18"],["4DAJ_A_0HKA2000_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",11,"ASP A 103;TYR A 104;SER A 107;ASN A 108;TRP A 155;THR A 187;ALA A 194;TRP A 400;TYR A 403;ASN A 404;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.9A);QNB A1162 (-4.2A);QNB A1162 (-4.8A);QNB A1162 ( 4.0A);QNB A1162 (-4.7A);QNB A1162 (-3.9A);QNB A1162 (-2.9A);QNB A1162 ( 4.0A)","0.59A","4dajA-3uonA:39.6","4dajA-3uonA:73.18"],["4DAJ_A_0HKA2000_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",11,"ASP A 103;TYR A 104;SER A 107;TRP A 155;THR A 187;ALA A 194;TRP A 400;TYR A 403;ASN A 404;TYR A 426;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.2A);QNB A1162 (-4.8A);QNB A1162 ( 4.0A);QNB A1162 (-4.7A);QNB A1162 (-3.9A);QNB A1162 (-2.9A);QNB A1162 ( 4.2A);QNB A1162 ( 4.0A)","0.74A","4dajA-3uonA:39.6","4dajA-3uonA:73.18"],["4DAJ_A_0HKA2000_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",6,"ASP A 103;TYR A 104;THR A 190;TRP A 400;ASN A 404;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-4.3A);QNB A1162 (-4.7A);QNB A1162 (-2.9A);QNB A1162 ( 4.0A)","1.45A","4dajA-3uonA:39.6","4dajA-3uonA:73.18"],["4DAJ_B_0HKB2000_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",5,"ASP A 103;TYR A 104;ALA A 191;TYR A 426;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-3.9A);QNB A1162 ( 4.2A);QNB A1162 ( 4.0A)","1.40A","4dajB-3uonA:39.8","4dajB-3uonA:73.18"],["4DAJ_B_0HKB2000_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",12,"ASP A 103;TYR A 104;SER A 107;TRP A 155;THR A 187;THR A 190;ALA A 194;TRP A 400;TYR A 403;ASN A 404;TYR A 426;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.2A);QNB A1162 (-4.8A);QNB A1162 (-4.3A);QNB A1162 ( 4.0A);QNB A1162 (-4.7A);QNB A1162 (-3.9A);QNB A1162 (-2.9A);QNB A1162 ( 4.2A);QNB A1162 ( 4.0A)","0.75A","4dajB-3uonA:39.8","4dajB-3uonA:73.18"],["4DAJ_B_0HKB2000_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",5,"ASP A 103;TYR A 104;THR A 187;ALA A 191;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-4.8A);QNB A1162 (-3.9A);QNB A1162 ( 4.0A)","1.29A","4dajB-3uonA:39.8","4dajB-3uonA:73.18"],["4DAJ_B_0HKB2000_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",6,"ASP A 103;TYR A 104;THR A 190;TRP A 400;ASN A 404;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-4.3A);QNB A1162 (-4.7A);QNB A1162 (-2.9A);QNB A1162 ( 4.0A)","1.43A","4dajB-3uonA:39.8","4dajB-3uonA:73.18"],["4DAJ_C_0HKC2000_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",11,"ASP A 103;TYR A 104;SER A 107;ASN A 108;TRP A 155;THR A 187;THR A 190;TRP A 400;TYR A 403;ASN A 404;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.9A);QNB A1162 (-4.2A);QNB A1162 (-4.8A);QNB A1162 (-4.3A);QNB A1162 (-4.7A);QNB A1162 (-3.9A);QNB A1162 (-2.9A);QNB A1162 ( 4.0A)","0.75A","4dajC-3uonA:39.6","4dajC-3uonA:73.18"],["4DAJ_C_0HKC2000_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",11,"ASP A 103;TYR A 104;SER A 107;TRP A 155;THR A 187;THR A 190;TRP A 400;TYR A 403;ASN A 404;TYR A 426;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.2A);QNB A1162 (-4.8A);QNB A1162 (-4.3A);QNB A1162 (-4.7A);QNB A1162 (-3.9A);QNB A1162 (-2.9A);QNB A1162 ( 4.2A);QNB A1162 ( 4.0A)","0.85A","4dajC-3uonA:39.6","4dajC-3uonA:73.18"],["4DAJ_D_0HKD2000_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",11,"ASP A 103;TYR A 104;SER A 107;ASN A 108;TRP A 155;THR A 187;THR A 190;TRP A 400;TYR A 403;ASN A 404;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.9A);QNB A1162 (-4.2A);QNB A1162 (-4.8A);QNB A1162 (-4.3A);QNB A1162 (-4.7A);QNB A1162 (-3.9A);QNB A1162 (-2.9A);QNB A1162 ( 4.0A)","0.62A","4dajD-3uonA:39.6","4dajD-3uonA:73.18"],["4DAJ_D_0HKD2000_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",11,"ASP A 103;TYR A 104;SER A 107;TRP A 155;THR A 187;THR A 190;TRP A 400;TYR A 403;ASN A 404;TYR A 426;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.2A);QNB A1162 (-4.8A);QNB A1162 (-4.3A);QNB A1162 (-4.7A);QNB A1162 (-3.9A);QNB A1162 (-2.9A);QNB A1162 ( 4.2A);QNB A1162 ( 4.0A)","0.76A","4dajD-3uonA:39.6","4dajD-3uonA:73.18"],["4DAJ_D_0HKD2000_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",6,"ASP A 103;TYR A 104;THR A 190;TRP A 400;ASN A 404;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-4.3A);QNB A1162 (-4.7A);QNB A1162 (-2.9A);QNB A1162 ( 4.0A)","1.48A","4dajD-3uonA:39.6","4dajD-3uonA:73.18"],["4NC3_A_ERMA1202_1","CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 2B AND E. COLI SOLUBLE CYTOCHROME B562","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",6,"LEU A 100;ASP A 103;SER A 107;PHE A 181;ALA A 194;TRP A 400","None;QNB A1162 (-3.1A);QNB A1162 (-3.4A);QNB A1162 (-4.4A);QNB A1162 ( 4.0A);QNB A1162 (-4.7A)","1.24A","4nc3A-3uonA:27.0","4nc3A-3uonA:28.51"],["4P7N_A_GCSA702_1","POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE N-DEACETYLASE","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",3,"ASP A 103;TYR A 104;TRP A  99","QNB A1162 (-3.1A);QNB A1162 (-4.0A);None","1.38A","4p7nA-3uonA:undetectable","4p7nA-3uonA:21.84"],["4TWD_C_377C401_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",4,"TYR A 403;ASN A 404;TYR A 104;PHE A 181","QNB A1162 (-3.9A);QNB A1162 (-2.9A);QNB A1162 (-4.0A);QNB A1162 (-4.4A)","1.26A","4twdB-3uonA:2.7;4twdC-3uonA:2.7","4twdB-3uonA:19.33;4twdC-3uonA:19.33"],["4TWD_C_377C402_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",4,"TYR A 403;ASN A 404;TYR A 104;PHE A 181","QNB A1162 (-3.9A);QNB A1162 (-2.9A);QNB A1162 (-4.0A);QNB A1162 (-4.4A)","1.31A","4twdC-3uonA:2.7;4twdD-3uonA:2.8","4twdC-3uonA:19.33;4twdD-3uonA:19.33"],["4TWD_H_377H401_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",4,"TYR A 403;ASN A 404;TYR A 104;PHE A 181","QNB A1162 (-3.9A);QNB A1162 (-2.9A);QNB A1162 (-4.0A);QNB A1162 (-4.4A)","1.32A","4twdG-3uonA:undetectable;4twdH-3uonA:1.7","4twdG-3uonA:19.33;4twdH-3uonA:19.33"],["4TWD_J_377J401_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",4,"TYR A 403;ASN A 404;TYR A 104;PHE A 181","QNB A1162 (-3.9A);QNB A1162 (-2.9A);QNB A1162 (-4.0A);QNB A1162 (-4.4A)","1.31A","4twdI-3uonA:undetectable;4twdJ-3uonA:undetectable","4twdI-3uonA:19.33;4twdJ-3uonA:19.33"],["4U14_A_0HKA2000_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M3","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",5,"ASP A 103;TYR A 104;ALA A 191;TYR A 426;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-3.9A);QNB A1162 ( 4.2A);QNB A1162 ( 4.0A)","1.49A","4u14A-3uonA:38.6","4u14A-3uonA:73.62"],["4U14_A_0HKA2000_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M3","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",12,"ILE A  72;ASP A 103;TYR A 104;SER A 107;TRP A 155;THR A 187;ALA A 191;ALA A 194;TRP A 400;ASN A 404;TYR A 426;CYH A 429","None;QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.2A);QNB A1162 (-4.8A);QNB A1162 (-3.9A);QNB A1162 ( 4.0A);QNB A1162 (-4.7A);QNB A1162 (-2.9A);QNB A1162 ( 4.2A);QNB A1162 ( 4.0A)","0.91A","4u14A-3uonA:38.6","4u14A-3uonA:73.62"],["4U14_A_0HKA2000_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M3","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",7,"ILE A  72;ASP A 103;TYR A 104;THR A 190;TRP A 400;ASN A 404;CYH A 429","None;QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-4.3A);QNB A1162 (-4.7A);QNB A1162 (-2.9A);QNB A1162 ( 4.0A)","1.43A","4u14A-3uonA:38.6","4u14A-3uonA:73.62"],["4U14_A_0HKA2000_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M3","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",6,"ILE A  72;TYR A 104;THR A 190;ALA A 194;TRP A 400;CYH A 429","None;QNB A1162 (-4.0A);QNB A1162 (-4.3A);QNB A1162 ( 4.0A);QNB A1162 (-4.7A);QNB A1162 ( 4.0A)","1.49A","4u14A-3uonA:38.6","4u14A-3uonA:73.62"],["4U15_A_0HKA2001_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARINIC ACETYLCHOLINE RECEPTOR M3","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",12,"ASP A 103;TYR A 104;SER A 107;TRP A 155;THR A 187;THR A 190;ALA A 191;ALA A 194;TRP A 400;ASN A 404;TYR A 426;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.2A);QNB A1162 (-4.8A);QNB A1162 (-4.3A);QNB A1162 (-3.9A);QNB A1162 ( 4.0A);QNB A1162 (-4.7A);QNB A1162 (-2.9A);QNB A1162 ( 4.2A);QNB A1162 ( 4.0A)","0.79A","4u15A-3uonA:39.0","4u15A-3uonA:65.11"],["4U15_A_0HKA2001_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARINIC ACETYLCHOLINE RECEPTOR M3","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",5,"ASP A 103;TYR A 104;THR A 187;ALA A 191;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-4.8A);QNB A1162 (-3.9A);QNB A1162 ( 4.0A)","1.23A","4u15A-3uonA:39.0","4u15A-3uonA:65.11"],["4U15_A_0HKA2001_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARINIC ACETYLCHOLINE RECEPTOR M3","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",6,"ASP A 103;TYR A 104;THR A 190;TRP A 400;ASN A 404;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-4.3A);QNB A1162 (-4.7A);QNB A1162 (-2.9A);QNB A1162 ( 4.0A)","1.43A","4u15A-3uonA:39.0","4u15A-3uonA:65.11"],["4U15_A_0HKA2001_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARINIC ACETYLCHOLINE RECEPTOR M3","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",6,"TYR A 104;SER A 107;TRP A 155;TRP A 400;TYR A 403;CYH A 429","QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.2A);QNB A1162 (-4.7A);QNB A1162 (-3.9A);QNB A1162 ( 4.0A)","1.47A","4u15A-3uonA:39.0","4u15A-3uonA:65.11"],["4U15_A_0HKA2001_2","MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARINIC ACETYLCHOLINE RECEPTOR M3","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",3,"ASN A 108;PHE A 195;TYR A 403","QNB A1162 (-4.9A);QNB A1162 (-4.4A);QNB A1162 (-3.9A)","0.53A","4u15A-3uonA:39.0","4u15A-3uonA:65.11"],["4U15_B_0HKB1201_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARINIC ACETYLCHOLINE RECEPTOR M3","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",11,"ASP A 103;TYR A 104;SER A 107;THR A 187;THR A 190;ALA A 191;ALA A 194;TRP A 400;TYR A 403;ASN A 404;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.8A);QNB A1162 (-4.3A);QNB A1162 (-3.9A);QNB A1162 ( 4.0A);QNB A1162 (-4.7A);QNB A1162 (-3.9A);QNB A1162 (-2.9A);QNB A1162 ( 4.0A)","0.52A","4u15B-3uonA:19.2","4u15B-3uonA:65.11"],["4U15_B_0HKB1201_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARINIC ACETYLCHOLINE RECEPTOR M3","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",5,"ASP A 103;TYR A 104;THR A 187;ALA A 191;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-4.8A);QNB A1162 (-3.9A);QNB A1162 ( 4.0A)","1.25A","4u15B-3uonA:19.2","4u15B-3uonA:65.11"],["4U15_B_0HKB1201_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARINIC ACETYLCHOLINE RECEPTOR M3","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",11,"TYR A 104;SER A 107;THR A 187;THR A 190;ALA A 191;ALA A 194;TRP A 400;TYR A 403;ASN A 404;TYR A 426;CYH A 429","QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.8A);QNB A1162 (-4.3A);QNB A1162 (-3.9A);QNB A1162 ( 4.0A);QNB A1162 (-4.7A);QNB A1162 (-3.9A);QNB A1162 (-2.9A);QNB A1162 ( 4.2A);QNB A1162 ( 4.0A)","0.73A","4u15B-3uonA:19.2","4u15B-3uonA:65.11"],["5CXV_A_0HKA501_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M1","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",5,"ASP A 103;TYR A 104;ALA A 191;TYR A 426;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-3.9A);QNB A1162 ( 4.2A);QNB A1162 ( 4.0A)","1.40A","5cxvA-3uonA:39.7","5cxvA-3uonA:68.90"],["5CXV_A_0HKA501_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M1","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",11,"ASP A 103;TYR A 104;SER A 107;TRP A 155;ALA A 191;ALA A 194;TRP A 400;TYR A 403;ASN A 404;TYR A 426;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.2A);QNB A1162 (-3.9A);QNB A1162 ( 4.0A);QNB A1162 (-4.7A);QNB A1162 (-3.9A);QNB A1162 (-2.9A);QNB A1162 ( 4.2A);QNB A1162 ( 4.0A)","0.74A","5cxvA-3uonA:39.7","5cxvA-3uonA:68.90"],["5CXV_A_0HKA501_2","MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M1","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",3,"THR A 187;THR A 190;PHE A 195","QNB A1162 (-4.8A);QNB A1162 (-4.3A);QNB A1162 (-4.4A)","0.51A","5cxvA-3uonA:39.7","5cxvA-3uonA:68.90"],["5DSG_A_0HKA1201_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",6,"ASP A 103;TYR A 104;SER A 107;THR A 187;TRP A 400;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.8A);QNB A1162 (-4.7A);QNB A1162 ( 4.0A)","1.39A","5dsgA-3uonA:39.7","5dsgA-3uonA:76.23"],["5DSG_A_0HKA1201_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",10,"ASP A 103;TYR A 104;SER A 107;TRP A 155;THR A 187;THR A 190;TRP A 400;TYR A 403;TYR A 426;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.2A);QNB A1162 (-4.8A);QNB A1162 (-4.3A);QNB A1162 (-4.7A);QNB A1162 (-3.9A);QNB A1162 ( 4.2A);QNB A1162 ( 4.0A)","0.91A","5dsgA-3uonA:39.7","5dsgA-3uonA:76.23"],["5DSG_A_0HKA1201_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",5,"ASP A 103;TYR A 104;THR A 187;ALA A 191;CYH A 429","QNB A1162 (-3.1A);QNB A1162 (-4.0A);QNB A1162 (-4.8A);QNB A1162 (-3.9A);QNB A1162 ( 4.0A)","1.37A","5dsgA-3uonA:39.7","5dsgA-3uonA:76.23"],["5DSG_A_0HKA1201_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",6,"TYR A 104;SER A 107;THR A 187;TRP A 400;ASN A 404;CYH A 429","QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.8A);QNB A1162 (-4.7A);QNB A1162 (-2.9A);QNB A1162 ( 4.0A)","1.47A","5dsgA-3uonA:39.7","5dsgA-3uonA:76.23"],["5DSG_A_0HKA1201_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",11,"TYR A 104;SER A 107;TRP A 155;THR A 187;THR A 190;ALA A 194;TRP A 400;TYR A 403;ASN A 404;TYR A 426;CYH A 429","QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.2A);QNB A1162 (-4.8A);QNB A1162 (-4.3A);QNB A1162 ( 4.0A);QNB A1162 (-4.7A);QNB A1162 (-3.9A);QNB A1162 (-2.9A);QNB A1162 ( 4.2A);QNB A1162 ( 4.0A)","0.75A","5dsgA-3uonA:39.7","5dsgA-3uonA:76.23"],["5DSG_B_0HKB1201_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",6,"TYR A 104;SER A 107;THR A 187;TRP A 400;ASN A 404;CYH A 429","QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.8A);QNB A1162 (-4.7A);QNB A1162 (-2.9A);QNB A1162 ( 4.0A)","1.48A","5dsgB-3uonA:38.3","5dsgB-3uonA:76.23"],["5DSG_B_0HKB1201_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",11,"TYR A 104;SER A 107;TRP A 155;THR A 187;THR A 190;ALA A 194;TRP A 400;TYR A 403;ASN A 404;TYR A 426;CYH A 429","QNB A1162 (-4.0A);QNB A1162 (-3.4A);QNB A1162 (-4.2A);QNB A1162 (-4.8A);QNB A1162 (-4.3A);QNB A1162 ( 4.0A);QNB A1162 (-4.7A);QNB A1162 (-3.9A);QNB A1162 (-2.9A);QNB A1162 ( 4.2A);QNB A1162 ( 4.0A)","0.73A","5dsgB-3uonA:38.3","5dsgB-3uonA:76.23"],["5HW8_A_FK5A201_1","FK506-BINDING PROTEIN 1;FK506-BINDING PROTEIN 1","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",5,"VAL A  95;TRP A  89;ILE A 178;ILE A  71;ILE A  72","None","1.07A","5hw8A-3uonA:undetectable;5hw8D-3uonA:undetectable","5hw8A-3uonA:12.69;5hw8D-3uonA:12.69"],["6B5V_A_ECLA1001_1","TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5;TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",4,"ILE A  48;LEU A  54;ILE A 392;ALA A 445","None","0.83A","6b5vA-3uonA:1.2;6b5vC-3uonA:0.0","6b5vA-3uonA:15.12;6b5vC-3uonA:15.12"],["6B5V_C_ECLC1001_1","TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5;TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",4,"ILE A  48;LEU A  54;ILE A 392;ALA A 445","None","0.83A","6b5vC-3uonA:0.0;6b5vD-3uonA:undetectable","6b5vC-3uonA:15.12;6b5vD-3uonA:15.12"],["6B5V_D_ECLD1001_1","TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5;TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Escherichia virus T4;Homo sapiens",4,"ALA A 445;ILE A  48;LEU A  54;ILE A 392","None","0.83A","6b5vB-3uonA:undetectable;6b5vD-3uonA:undetectable","6b5vB-3uonA:15.12;6b5vD-3uonA:15.12"],["6CDU_G_EY4G501_0","CHIMERIC ALPHA1GABAA RECEPTOR","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Homo sapiens;Escherichia virus T4",4,"ILE A 398;PRO A 402;ILE A 435;THR A 434","None","0.94A","6cduF-3uonA:3.7;6cduG-3uonA:3.8","6cduF-3uonA:22.13;6cduG-3uonA:22.13"],["6DRX_A_H8GA1201_0","5HT2B RECEPTOR, BRIL CHIMERA","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Homo sapiens;Escherichia virus T4",5,"TRP A  99;LEU A 100;SER A 107;PHE A 181;ALA A 194","None;None;QNB A1162 (-3.4A);QNB A1162 (-4.4A);QNB A1162 ( 4.0A)","0.99A","6drxA-3uonA:26.7","6drxA-3uonA:27.97"],["6DRX_A_H8GA1201_0","5HT2B RECEPTOR, BRIL CHIMERA","3uon","HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN","Homo sapiens;Escherichia virus T4",5,"TRP A  99;LEU A 100;SER A 107;PHE A 181;TRP A 400","None;None;QNB A1162 (-3.4A);QNB A1162 (-4.4A);QNB A1162 (-4.7A)","1.31A","6drxA-3uonA:26.7","6drxA-3uonA:27.97"]]