SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3up9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3up9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Actinomyces
odontolyticus) 		5 / 9 VAL A 188
LEU A 157
ILE A 141
ALA A 203
ALA A 153
 None
 1.12A 3mdvA-3up9A:
undetectable		 3mdvA-3up9A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_2
(ADENOSINE KINASE,
PUTATIVE)		 3up9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Actinomyces
odontolyticus) 		4 / 5 LEU A 100
ALA A 103
MET A 300
ASN A 149
 None
 1.25A 3uq6A-3up9A:
undetectable		 3uq6A-3up9A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3up9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Actinomyces
odontolyticus) 		4 / 8 ILE A  53
LEU A 255
VAL A  43
GLY A  44
 None
 0.89A 3w1wA-3up9A:
undetectable		 3w1wA-3up9A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 3up9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Actinomyces
odontolyticus) 		4 / 7 SER A 196
GLY A 207
GLY A 123
GLU A 225
 None
 0.81A 4koeA-3up9A:
undetectable
4koeB-3up9A:
undetectable
4koeD-3up9A:
undetectable		 4koeA-3up9A:
21.38
4koeB-3up9A:
21.38
4koeD-3up9A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 3up9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Actinomyces
odontolyticus) 		4 / 6 SER A 131
LEU A 132
ASP A 133
LEU A 222
 None
None
PG4  A 303 (-4.6A)
None
 0.99A 4wozA-3up9A:
undetectable
4wozB-3up9A:
undetectable		 4wozA-3up9A:
23.27
4wozB-3up9A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 3up9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Actinomyces
odontolyticus) 		4 / 7 GLY A 207
GLY A 123
GLU A 225
SER A 196
 None
 0.83A 4z53A-3up9A:
undetectable
4z53B-3up9A:
undetectable		 4z53A-3up9A:
16.53
4z53B-3up9A:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3up9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Actinomyces
odontolyticus) 		3 / 3 VAL A 204
VAL A 124
GLN A 160
 None
 0.66A 5qgyA-3up9A:
undetectable		 5qgyA-3up9A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3up9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Actinomyces
odontolyticus) 		3 / 3 VAL A 204
VAL A 124
GLN A 160
 None
 0.67A 5qgzA-3up9A:
undetectable		 5qgzA-3up9A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3up9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Actinomyces
odontolyticus) 		3 / 3 VAL A 204
VAL A 124
GLN A 160
 None
 0.67A 5qh2A-3up9A:
undetectable		 5qh2A-3up9A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3up9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Actinomyces
odontolyticus) 		3 / 3 VAL A 204
VAL A 124
GLN A 160
 None
 0.66A 5qh3A-3up9A:
undetectable		 5qh3A-3up9A:
20.73