SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ups'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 3ups IOJAP-LIKE PROTEIN
(Zymomonas
mobilis) 		4 / 7 GLN A  60
ASP A  30
LEU A  93
SER A  54
 None
 1.09A 1ig3A-3upsA:
undetectable
1ig3B-3upsA:
undetectable		 1ig3A-3upsA:
20.77
1ig3B-3upsA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ups IOJAP-LIKE PROTEIN
(Zymomonas
mobilis) 		4 / 6 THR A  24
VAL A  23
LEU A  68
ALA A  32
 None
 1.04A 2e1qC-3upsA:
undetectable		 2e1qC-3upsA:
7.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3ups IOJAP-LIKE PROTEIN
(Zymomonas
mobilis) 		5 / 9 LEU A  22
LEU A  20
LEU A  19
ILE A  98
LEU A  27
 None
 1.16A 2f78A-3upsA:
undetectable		 2f78A-3upsA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3ups IOJAP-LIKE PROTEIN
(Zymomonas
mobilis) 		5 / 9 LEU A  22
LEU A  20
LEU A  19
ILE A  98
LEU A  27
 None
 1.20A 2f7aB-3upsA:
undetectable		 2f7aB-3upsA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 3ups IOJAP-LIKE PROTEIN
(Zymomonas
mobilis) 		4 / 6 ASP A  97
LEU A  40
ASP A  94
LEU A  92
 None
 1.00A 3bj8C-3upsA:
undetectable
3bj8D-3upsA:
undetectable		 3bj8C-3upsA:
21.69
3bj8D-3upsA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 3ups IOJAP-LIKE PROTEIN
(Zymomonas
mobilis) 		5 / 12 LEU A  92
LEU A  22
ILE A 100
ILE A  99
ALA A  47
 None
 0.97A 4ltwA-3upsA:
undetectable		 4ltwA-3upsA:
22.13