SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3urg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CZH_A_D2VA602_2 (CYTOCHROME P450 2R1)	3urg	ALR1010 PROTEIN (Nostoc sp. PCC 7120)	3 / 3	LEU A 117 GLU A 101 ILE A 100	None	0.59A	3czhA-3urgA: undetectable	3czhA-3urgA: 15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ME6_A_CGEA501_1 (CYTOCHROME P450 2B4)	3urg	ALR1010 PROTEIN (Nostoc sp. PCC 7120)	5 / 10	VAL A 65 PHE A 42 ILE A 100 ALA A 112 VAL A 105	None NA A 127 (-4.5A) None None None	0.88A	3me6A-3urgA: undetectable	3me6A-3urgA: 14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ME6_C_CGEC501_1 (CYTOCHROME P450 2B4)	3urg	ALR1010 PROTEIN (Nostoc sp. PCC 7120)	5 / 9	VAL A 65 PHE A 42 ILE A 100 ALA A 112 VAL A 105	None NA A 127 (-4.5A) None None None	0.93A	3me6C-3urgA: undetectable	3me6C-3urgA: 14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ME6_D_CGED501_1 (CYTOCHROME P450 2B4)	3urg	ALR1010 PROTEIN (Nostoc sp. PCC 7120)	5 / 9	VAL A 65 PHE A 42 ILE A 100 ALA A 112 VAL A 105	None NA A 127 (-4.5A) None None None	0.89A	3me6D-3urgA: undetectable	3me6D-3urgA: 14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DC3_A_ADNA401_2 (ADENOSINE KINASE)	3urg	ALR1010 PROTEIN (Nostoc sp. PCC 7120)	4 / 4	LEU A 66 ILE A 100 GLY A 67 PHE A 44	None	1.05A	4dc3A-3urgA: undetectable	4dc3A-3urgA: 22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X5I_A_FOLA201_1 (DIHYDROFOLATE REDUCTASE)	3urg	ALR1010 PROTEIN (Nostoc sp. PCC 7120)	3 / 3	ASP A 106 ARG A 10 ARG A 13	None	0.86A	4x5iA-3urgA: undetectable	4x5iA-3urgA: 25.29

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3CZH_A_D2VA602_2","CYTOCHROME P450 2R1","3urg","ALR1010 PROTEIN","Nostoc sp. PCC 7120",3,"LEU A 117;GLU A 101;ILE A 100","None","0.59A","3czhA-3urgA:undetectable","3czhA-3urgA:15.90"],["3ME6_A_CGEA501_1","CYTOCHROME P450 2B4","3urg","ALR1010 PROTEIN","Nostoc sp. PCC 7120",5,"VAL A  65;PHE A  42;ILE A 100;ALA A 112;VAL A 105","None; NA A 127 (-4.5A);None;None;None","0.88A","3me6A-3urgA:undetectable","3me6A-3urgA:14.71"],["3ME6_C_CGEC501_1","CYTOCHROME P450 2B4","3urg","ALR1010 PROTEIN","Nostoc sp. PCC 7120",5,"VAL A  65;PHE A  42;ILE A 100;ALA A 112;VAL A 105","None; NA A 127 (-4.5A);None;None;None","0.93A","3me6C-3urgA:undetectable","3me6C-3urgA:14.71"],["3ME6_D_CGED501_1","CYTOCHROME P450 2B4","3urg","ALR1010 PROTEIN","Nostoc sp. PCC 7120",5,"VAL A  65;PHE A  42;ILE A 100;ALA A 112;VAL A 105","None; NA A 127 (-4.5A);None;None;None","0.89A","3me6D-3urgA:undetectable","3me6D-3urgA:14.71"],["4DC3_A_ADNA401_2","ADENOSINE KINASE","3urg","ALR1010 PROTEIN","Nostoc sp. PCC 7120",4,"LEU A  66;ILE A 100;GLY A  67;PHE A  44","None","1.05A","4dc3A-3urgA:undetectable","4dc3A-3urgA:22.70"],["4X5I_A_FOLA201_1","DIHYDROFOLATE REDUCTASE","3urg","ALR1010 PROTEIN","Nostoc sp. PCC 7120",3,"ASP A 106;ARG A  10;ARG A  13","None","0.86A","4x5iA-3urgA:undetectable","4x5iA-3urgA:25.29"]]