SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3urr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 3urr PTS IIA-LIKE
NITROGEN-REGULATORY
PROTEIN PTSN
(Burkholderia
thailandensis) 		4 / 6 LEU A 104
ALA A  79
LEU A  77
VAL A  81
 None
 1.08A 1sn5A-3urrA:
undetectable		 1sn5A-3urrA:
27.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3urr PTS IIA-LIKE
NITROGEN-REGULATORY
PROTEIN PTSN
(Burkholderia
thailandensis) 		4 / 6 ARG A  82
ILE A  15
GLY A  16
ALA A  84
 None
 0.95A 1wmqA-3urrA:
undetectable		 1wmqA-3urrA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3urr PTS IIA-LIKE
NITROGEN-REGULATORY
PROTEIN PTSN
(Burkholderia
thailandensis) 		4 / 6 ARG A  82
ILE A  15
GLY A  16
ALA A  84
 None
 0.96A 1wmqB-3urrA:
undetectable		 1wmqB-3urrA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3urr PTS IIA-LIKE
NITROGEN-REGULATORY
PROTEIN PTSN
(Burkholderia
thailandensis) 		4 / 6 ARG A  82
ILE A  15
GLY A  16
ALA A  84
 None
 0.96A 1wpuA-3urrA:
undetectable		 1wpuA-3urrA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3urr PTS IIA-LIKE
NITROGEN-REGULATORY
PROTEIN PTSN
(Burkholderia
thailandensis) 		4 / 6 ARG A  82
ILE A  15
GLY A  16
ALA A  84
 None
 0.97A 1wpuB-3urrA:
1.8		 1wpuB-3urrA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3urr PTS IIA-LIKE
NITROGEN-REGULATORY
PROTEIN PTSN
(Burkholderia
thailandensis) 		4 / 6 ARG A  82
ILE A  15
GLY A  16
ALA A  84
 None
 0.95A 1wrqA-3urrA:
undetectable		 1wrqA-3urrA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3urr PTS IIA-LIKE
NITROGEN-REGULATORY
PROTEIN PTSN
(Burkholderia
thailandensis) 		4 / 6 ARG A  82
ILE A  15
GLY A  16
ALA A  84
 None
 0.95A 1wrqB-3urrA:
undetectable		 1wrqB-3urrA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3urr PTS IIA-LIKE
NITROGEN-REGULATORY
PROTEIN PTSN
(Burkholderia
thailandensis) 		4 / 5 PHE A  89
THR A  57
LEU A  59
ALA A  91
 None
None
None
PO4  A 154 (-4.8A)
 1.34A 2e1qD-3urrA:
undetectable		 2e1qD-3urrA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 3urr PTS IIA-LIKE
NITROGEN-REGULATORY
PROTEIN PTSN
(Burkholderia
thailandensis) 		4 / 4 ARG A  41
GLY A  30
GLU A  34
SER A  21
 None
 1.36A 2xctS-3urrA:
undetectable
2xctU-3urrA:
undetectable		 2xctS-3urrA:
14.42
2xctU-3urrA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3urr PTS IIA-LIKE
NITROGEN-REGULATORY
PROTEIN PTSN
(Burkholderia
thailandensis) 		5 / 12 ILE A 120
PHE A 102
PHE A  26
LEU A  48
PHE A  89
 None
 1.34A 3apwB-3urrA:
undetectable		 3apwB-3urrA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 3urr PTS IIA-LIKE
NITROGEN-REGULATORY
PROTEIN PTSN
(Burkholderia
thailandensis) 		4 / 8 ALA A  64
GLY A  58
THR A  57
GLU A  52
 None
 0.87A 3rglA-3urrA:
undetectable		 3rglA-3urrA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 3urr PTS IIA-LIKE
NITROGEN-REGULATORY
PROTEIN PTSN
(Burkholderia
thailandensis) 		4 / 5 LEU A 104
ALA A  79
LEU A  77
VAL A  14
 None
 0.69A 5cr1A-3urrA:
undetectable		 5cr1A-3urrA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 3urr PTS IIA-LIKE
NITROGEN-REGULATORY
PROTEIN PTSN
(Burkholderia
thailandensis) 		4 / 5 LEU A 104
ALA A  79
LEU A  77
VAL A  81
 None
 1.18A 5cr1A-3urrA:
undetectable		 5cr1A-3urrA:
22.09