SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ury'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 3ury EXOTOXIN
(Staphylococcus
aureus) 		4 / 4 VAL A 215
ALA A 213
LEU A 245
PHE A 233
 None
 1.26A 1q97B-3uryA:
undetectable		 1q97B-3uryA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ury EXOTOXIN
(Staphylococcus
aureus) 		3 / 3 PHE A 247
VAL A 305
ILE A 303
 None
 0.58A 4emaA-3uryA:
undetectable		 4emaA-3uryA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3ury EXOTOXIN
(Staphylococcus
aureus) 		5 / 12 ILE A 300
LEU A 242
ILE A 268
ARG A 250
ILE A 303
 None
 1.10A 4x5jA-3uryA:
undetectable		 4x5jA-3uryA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 3ury EXOTOXIN
(Staphylococcus
aureus) 		3 / 3 LEU A 253
LEU A 282
ARG A 250
 None
 0.66A 6fgcA-3uryA:
undetectable		 6fgcA-3uryA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 3ury EXOTOXIN
(Staphylococcus
aureus) 		3 / 3 LEU A 253
LEU A 282
ARG A 250
 None
 0.67A 6fgdA-3uryA:
undetectable		 6fgdA-3uryA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 3ury EXOTOXIN
(Staphylococcus
aureus) 		5 / 10 ASP A 156
TYR A 160
VAL A 184
GLY A 200
VAL A 180
 CL  A 309 (-4.5A)
None
None
None
None
 1.48A 6hu9L-3uryA:
undetectable
6hu9P-3uryA:
undetectable
6hu9T-3uryA:
undetectable		 6hu9L-3uryA:
18.10
6hu9P-3uryA:
20.81
6hu9T-3uryA:
17.99