SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uss'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 PRO A 128
ALA A 147
PHE A 148
SER A 153
 None
 1.25A 1lqtA-3ussA:
undetectable		 1lqtA-3ussA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 PRO A 128
ALA A 147
PHE A 148
SER A 153
 None
 1.24A 1lquA-3ussA:
undetectable		 1lquA-3ussA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_F_BEZF511_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 105
GLU A 127
PHE A 148
ALA A 103
 SO4  A 216 (-4.3A)
None
None
None
 1.45A 1oniE-3ussA:
0.0
1oniF-3ussA:
0.0		 1oniE-3ussA:
20.72
1oniF-3ussA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 126
TYR A 159
ILE A  97
HIS A  91
HIS A  89
 None
SO4  A 215 (-4.6A)
None
FE2  A 212 ( 3.2A)
FE2  A 212 ( 3.2A)
 1.33A 1tmxB-3ussA:
undetectable		 1tmxB-3ussA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 HIS A  89
HIS A  91
HIS A 142
VAL A 144
PHE A  78
 FE2  A 212 ( 3.2A)
FE2  A 212 ( 3.2A)
FE2  A 212 (-3.3A)
None
SO4  A 215 (-4.0A)
 1.09A 1ydbA-3ussA:
undetectable		 1ydbA-3ussA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A69_C_RPTC8001_1
(DNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
RNA POLYMERASE SIGMA
FACTOR RPOD)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 GLN A 107
PHE A 171
HIS A  89
SER A 145
ILE A  85
 None
None
FE2  A 212 ( 3.2A)
None
None
 1.49A 2a69C-3ussA:
0.0
2a69F-3ussA:
0.0		 2a69C-3ussA:
11.51
2a69F-3ussA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 142
HIS A  91
HIS A 157
VAL A 131
SER A 106
 FE2  A 212 (-3.3A)
FE2  A 212 ( 3.2A)
SO4  A 215 (-4.1A)
None
None
 1.18A 2zweA-3ussA:
undetectable
2zweB-3ussA:
undetectable		 2zweA-3ussA:
23.13
2zweB-3ussA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 142
HIS A  91
HIS A 157
VAL A 131
SER A 106
 FE2  A 212 (-3.3A)
FE2  A 212 ( 3.2A)
SO4  A 215 (-4.1A)
None
None
 1.14A 2zwfA-3ussA:
undetectable
2zwfB-3ussA:
undetectable		 2zwfA-3ussA:
23.13
2zwfB-3ussA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 142
HIS A  91
HIS A 157
VAL A 131
SER A 106
 FE2  A 212 (-3.3A)
FE2  A 212 ( 3.2A)
SO4  A 215 (-4.1A)
None
None
 1.12A 2zwgA-3ussA:
undetectable
2zwgB-3ussA:
undetectable		 2zwgA-3ussA:
23.13
2zwgB-3ussA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 TYR A  60
VAL A  42
VAL A  76
ILE A 154
 None
 1.33A 3ms9B-3ussA:
undetectable		 3ms9B-3ussA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_C_PM6C1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 GLU A 127
ARG A 123
ALA A 103
ALA A 147
 None
SO4  A 216 (-3.8A)
None
None
 1.19A 3ns1C-3ussA:
undetectable		 3ns1C-3ussA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVC_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 GLN A  62
HIS A  91
HIS A 142
HIS A  89
 SO4  A 215 ( 4.5A)
FE2  A 212 ( 3.2A)
FE2  A 212 (-3.3A)
FE2  A 212 ( 3.2A)
 1.04A 3nvcA-3ussA:
6.9		 3nvcA-3ussA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 PRO A 117
ILE A 138
SER A 172
 None
 0.30A 5fsaA-3ussA:
undetectable		 5fsaA-3ussA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 ILE A 192
PRO A 190
LEU A   7
ILE A 156
LEU A 100
 None
NA  A 218 ( 4.2A)
None
None
None
 1.18A 5ienB-3ussA:
undetectable		 5ienB-3ussA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 142
HIS A  91
HIS A 157
VAL A 131
SER A 106
 FE2  A 212 (-3.3A)
FE2  A 212 ( 3.2A)
SO4  A 215 (-4.1A)
None
None
 1.18A 5z0fA-3ussA:
undetectable
5z0fB-3ussA:
undetectable		 5z0fA-3ussA:
17.54
5z0fB-3ussA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 157
HIS A  91
HIS A 142
VAL A  88
SER A 106
 SO4  A 215 (-4.1A)
FE2  A 212 ( 3.2A)
FE2  A 212 (-3.3A)
None
None
 1.32A 5z0fA-3ussA:
undetectable
5z0fB-3ussA:
undetectable		 5z0fA-3ussA:
17.54
5z0fB-3ussA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 142
HIS A  91
HIS A 157
VAL A 131
SER A 106
 FE2  A 212 (-3.3A)
FE2  A 212 ( 3.2A)
SO4  A 215 (-4.1A)
None
None
 1.18A 5z0gA-3ussA:
undetectable
5z0gB-3ussA:
undetectable		 5z0gA-3ussA:
17.54
5z0gB-3ussA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 157
HIS A  91
HIS A 142
VAL A  88
SER A 106
 SO4  A 215 (-4.1A)
FE2  A 212 ( 3.2A)
FE2  A 212 (-3.3A)
None
None
 1.32A 5z0gA-3ussA:
undetectable
5z0gB-3ussA:
undetectable		 5z0gA-3ussA:
17.54
5z0gB-3ussA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 142
HIS A  91
HIS A 157
VAL A 131
SER A 106
 FE2  A 212 (-3.3A)
FE2  A 212 ( 3.2A)
SO4  A 215 (-4.1A)
None
None
 1.14A 5z0hA-3ussA:
undetectable
5z0hB-3ussA:
undetectable		 5z0hA-3ussA:
17.54
5z0hB-3ussA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 142
HIS A  91
HIS A 157
VAL A 131
SER A 106
 FE2  A 212 (-3.3A)
FE2  A 212 ( 3.2A)
SO4  A 215 (-4.1A)
None
None
 1.14A 5z0iA-3ussA:
undetectable
5z0iB-3ussA:
undetectable		 5z0iA-3ussA:
17.54
5z0iB-3ussA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 157
HIS A  91
HIS A 142
VAL A  88
SER A 106
 SO4  A 215 (-4.1A)
FE2  A 212 ( 3.2A)
FE2  A 212 (-3.3A)
None
None
 1.32A 5z0iA-3ussA:
undetectable
5z0iB-3ussA:
undetectable		 5z0iA-3ussA:
17.54
5z0iB-3ussA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 142
HIS A  91
HIS A 157
VAL A 131
SER A 106
 FE2  A 212 (-3.3A)
FE2  A 212 ( 3.2A)
SO4  A 215 (-4.1A)
None
None
 1.19A 5z0jA-3ussA:
undetectable
5z0jB-3ussA:
undetectable		 5z0jA-3ussA:
17.54
5z0jB-3ussA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 142
HIS A  91
HIS A 157
VAL A 131
SER A 106
 FE2  A 212 (-3.3A)
FE2  A 212 ( 3.2A)
SO4  A 215 (-4.1A)
None
None
 1.18A 5z0kA-3ussA:
undetectable
5z0kB-3ussA:
undetectable		 5z0kA-3ussA:
17.54
5z0kB-3ussA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 142
HIS A  91
HIS A 157
VAL A 131
SER A 106
 FE2  A 212 (-3.3A)
FE2  A 212 ( 3.2A)
SO4  A 215 (-4.1A)
None
None
 1.12A 5z0lA-3ussA:
undetectable
5z0lB-3ussA:
undetectable		 5z0lA-3ussA:
17.54
5z0lB-3ussA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 157
HIS A  91
HIS A 142
VAL A  88
SER A 106
 SO4  A 215 (-4.1A)
FE2  A 212 ( 3.2A)
FE2  A 212 (-3.3A)
None
None
 1.33A 5z0lA-3ussA:
undetectable
5z0lB-3ussA:
undetectable		 5z0lA-3ussA:
17.54
5z0lB-3ussA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 142
HIS A  91
HIS A 157
VAL A 131
SER A 106
 FE2  A 212 (-3.3A)
FE2  A 212 ( 3.2A)
SO4  A 215 (-4.1A)
None
None
 1.14A 5z0mA-3ussA:
undetectable
5z0mB-3ussA:
undetectable		 5z0mA-3ussA:
17.54
5z0mB-3ussA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3uss PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 142
HIS A  89
ARG A 168
 FE2  A 212 (-3.3A)
FE2  A 212 ( 3.2A)
SO4  A 215 (-2.9A)
 0.97A 6b58A-3ussA:
undetectable		 6b58A-3ussA:
16.76