SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3usw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 3usw FLAGELLAR MOTOR
SWITCH PROTEIN
(Helicobacter
pylori) 		5 / 12 ARG A 293
PHE A 286
ALA A 294
ILE A 259
ILE A 262
 None
 1.29A 2bjfA-3uswA:
undetectable		 2bjfA-3uswA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_A_KKKA413_1
(FLAVOHEMOGLOBIN)		 3usw FLAGELLAR MOTOR
SWITCH PROTEIN
(Helicobacter
pylori) 		4 / 8 ILE A 125
GLN A 129
LEU A 130
LEU A 191
 None
 0.81A 3ozwA-3uswA:
undetectable		 3ozwA-3uswA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QT0_A_486A4_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3usw FLAGELLAR MOTOR
SWITCH PROTEIN
(Helicobacter
pylori) 		4 / 4 LYS A 330
GLN A 325
ILE A 251
LEU A 263
 None
 1.35A 3qt0A-3uswA:
undetectable		 3qt0A-3uswA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 3usw FLAGELLAR MOTOR
SWITCH PROTEIN
(Helicobacter
pylori) 		6 / 12 LEU A 195
LEU A 122
ASN A 153
MET A 149
ALA A 131
ILE A 145
 None
 1.38A 3ut5D-3uswA:
undetectable		 3ut5D-3uswA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 3usw FLAGELLAR MOTOR
SWITCH PROTEIN
(Helicobacter
pylori) 		5 / 12 LEU A 271
ILE A 323
ALA A 316
ILE A 251
PHE A 248
 None
 1.18A 4rp8C-3uswA:
undetectable		 4rp8C-3uswA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 3usw FLAGELLAR MOTOR
SWITCH PROTEIN
(Helicobacter
pylori) 		5 / 12 SER A 278
LEU A 275
VAL A 252
PHE A 286
LEU A 271
 None
 1.38A 5jo9A-3uswA:
undetectable		 5jo9A-3uswA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3usw FLAGELLAR MOTOR
SWITCH PROTEIN
(Helicobacter
pylori) 		4 / 6 ILE A 169
ILE A 125
LEU A 122
HIS A 148
 None
 0.94A 5vkqB-3uswA:
undetectable
5vkqC-3uswA:
undetectable		 5vkqB-3uswA:
10.58
5vkqC-3uswA:
10.58