SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ut3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		6 / 12 LEU A 275
PHE A 358
PHE A 360
GLN A 375
PRO A 379
TYR A 228
 None
 1.23A 1drfA-3ut3A:
undetectable		 1drfA-3ut3A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 6 LEU A 151
VAL A 140
VAL A 324
GLN A 322
 None
 0.99A 1e7aB-3ut3A:
undetectable		 1e7aB-3ut3A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_A_IBPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		5 / 9 VAL A 361
LEU A 254
ILE A 223
ALA A 238
LEU A 359
 None
 1.12A 1eqgA-3ut3A:
undetectable		 1eqgA-3ut3A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 7 GLU A 327
LEU A 280
VAL A 376
LEU A 275
 None
 0.95A 1hk3A-3ut3A:
undetectable		 1hk3A-3ut3A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 6 LYS A 323
ALA A 168
SER A  92
THR A  94
 None
 0.92A 1ictB-3ut3A:
undetectable		 1ictB-3ut3A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 8 LYS A 323
GLU A 283
ALA A 168
THR A  94
 None
 0.70A 1ie4B-3ut3A:
undetectable
1ie4D-3ut3A:
undetectable		 1ie4B-3ut3A:
18.01
1ie4D-3ut3A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		5 / 12 THR A  50
PHE A 299
LEU A 290
VAL A  19
ALA A  40
 None
 1.28A 1q23D-3ut3A:
undetectable
1q23E-3ut3A:
undetectable		 1q23D-3ut3A:
19.74
1q23E-3ut3A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U72_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		5 / 12 LEU A 275
PHE A 358
GLN A 375
PRO A 379
TYR A 228
 None
 1.25A 1u72A-3ut3A:
undetectable		 1u72A-3ut3A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 6 ARG A  18
VAL A  39
LEU A  43
ALA A  61
 None
 1.09A 2e1qA-3ut3A:
undetectable		 2e1qA-3ut3A:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		3 / 3 SER A 182
THR A 177
GLN A 204
 None
 0.85A 2fk8A-3ut3A:
undetectable		 2fk8A-3ut3A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 6 LEU A 293
LEU A  43
MET A 295
GLU A 291
 None
 1.25A 2kuhA-3ut3A:
undetectable		 2kuhA-3ut3A:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 6 LYS A 323
GLU A 283
ALA A 168
THR A  94
 None
 0.55A 2roxB-3ut3A:
undetectable		 2roxB-3ut3A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_0
(DIHYDROFOLATE
REDUCTASE)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		5 / 12 LEU A 275
PHE A 358
PHE A 360
ASN A  31
TYR A 228
 None
 1.05A 2w3bB-3ut3A:
undetectable		 2w3bB-3ut3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_A_FOLA1188_0
(DIHYDROFOLATE
REDUCTASE)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		5 / 12 LEU A 275
PHE A 358
PHE A 360
ASN A  31
TYR A 228
 None
 1.04A 2w3mA-3ut3A:
undetectable		 2w3mA-3ut3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_A_FOLA1188_0
(DIHYDROFOLATE
REDUCTASE)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		5 / 12 LEU A 275
PHE A 358
PHE A 360
GLN A 375
TYR A 228
 None
 1.09A 2w3mA-3ut3A:
undetectable		 2w3mA-3ut3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_B_FOLB1188_0
(DIHYDROFOLATE
REDUCTASE)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		5 / 12 LEU A 275
PHE A 358
PHE A 360
ASN A  31
TYR A 228
 None
 1.11A 2w3mB-3ut3A:
undetectable		 2w3mB-3ut3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_B_FOLB1188_0
(DIHYDROFOLATE
REDUCTASE)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		5 / 12 LEU A 275
PHE A 358
PHE A 360
GLN A 375
TYR A 228
 None
 1.14A 2w3mB-3ut3A:
undetectable		 2w3mB-3ut3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 8 THR A  49
GLN A  47
MET A  62
ILE A  58
 None
 1.14A 2xytH-3ut3A:
undetectable		 2xytH-3ut3A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 7 THR A  49
GLN A  47
MET A  62
ILE A  58
 None
 1.13A 2xytI-3ut3A:
undetectable		 2xytI-3ut3A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 5 THR A  93
THR A 369
HIS A 364
LEU A 233
 None
 1.23A 2zj0A-3ut3A:
undetectable		 2zj0A-3ut3A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 5 THR A  93
THR A 369
HIS A 364
LEU A 233
 None
 1.16A 3ce6C-3ut3A:
undetectable		 3ce6C-3ut3A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 6 LYS A 323
ALA A 168
SER A  92
THR A  94
 None
 0.58A 3cfqA-3ut3A:
undetectable		 3cfqA-3ut3A:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 7 LYS A 323
ALA A 168
SER A  92
THR A  94
 None
 0.93A 3cfqA-3ut3A:
undetectable
3cfqB-3ut3A:
undetectable		 3cfqA-3ut3A:
15.78
3cfqB-3ut3A:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_C_VIAC901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 7 MET A 235
LEU A 224
PHE A 358
VAL A 376
 None
 1.06A 3jwqC-3ut3A:
undetectable		 3jwqC-3ut3A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_C_FLRC700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		5 / 12 VAL A 140
LEU A 286
LEU A 151
VAL A  42
GLY A  38
 None
 0.95A 3rr3C-3ut3A:
undetectable		 3rr3C-3ut3A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_D_FLRD700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		5 / 12 VAL A 140
LEU A 286
LEU A 151
VAL A  42
GLY A  38
 None
 0.95A 3rr3D-3ut3A:
undetectable		 3rr3D-3ut3A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 6 ASP A 297
GLY A  52
ASP A 305
THR A  50
 None
 1.17A 3vqrA-3ut3A:
undetectable		 3vqrA-3ut3A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 5 ASP A 297
GLY A  52
ASP A 305
THR A  50
 None
 1.17A 3vqrB-3ut3A:
undetectable		 3vqrB-3ut3A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 5 GLU A  90
GLY A 173
TYR A 170
GLU A 327
 None
 1.38A 3w9tA-3ut3A:
undetectable		 3w9tA-3ut3A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 5 GLU A  90
GLY A 173
TYR A 170
GLU A 327
 None
 1.37A 3w9tC-3ut3A:
undetectable		 3w9tC-3ut3A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 5 GLU A  90
GLY A 173
TYR A 170
GLU A 327
 None
 1.38A 3w9tD-3ut3A:
undetectable		 3w9tD-3ut3A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 5 GLU A  90
GLY A 173
TYR A 170
GLU A 327
 None
 1.38A 3w9tG-3ut3A:
undetectable		 3w9tG-3ut3A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 6 LYS A 323
ALA A 168
SER A  92
THR A  94
 None
 0.64A 4i89A-3ut3A:
undetectable		 4i89A-3ut3A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KEB_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		5 / 12 LEU A 275
PHE A 358
PHE A 360
ASN A  31
TYR A 228
 None
 1.02A 4kebB-3ut3A:
undetectable		 4kebB-3ut3A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KEB_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		5 / 12 LEU A 275
PHE A 358
PHE A 360
GLN A 375
TYR A 228
 None
 1.08A 4kebB-3ut3A:
undetectable		 4kebB-3ut3A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		5 / 12 LEU A 275
PHE A 358
PHE A 360
PRO A 379
TYR A 228
 None
 1.02A 4m6kA-3ut3A:
undetectable		 4m6kA-3ut3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_A_QDNA602_1
(CYTOCHROME P450 2D6)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		5 / 11 LEU A  82
GLY A  38
LEU A  78
ALA A   9
SER A  13
 None
 1.14A 4wnuA-3ut3A:
undetectable		 4wnuA-3ut3A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		3 / 3 MET A  83
ASP A  95
PHE A 117
 None
 0.80A 4xeyA-3ut3A:
undetectable		 4xeyA-3ut3A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		3 / 3 MET A  83
ASP A  95
PHE A 117
 None
 0.82A 4xeyB-3ut3A:
undetectable		 4xeyB-3ut3A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 6 LYS A 323
ALA A 168
SER A  92
THR A  94
 None
 0.86A 5bojA-3ut3A:
undetectable		 5bojA-3ut3A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IM2_A_BEZA401_0
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		5 / 12 VAL A 284
LEU A 290
LEU A  43
PHE A  34
GLN A 322
 None
 1.20A 5im2A-3ut3A:
undetectable		 5im2A-3ut3A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 6 LYS A 323
ALA A 168
SER A  92
THR A  94
 None
 0.91A 5l4iA-3ut3A:
undetectable		 5l4iA-3ut3A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		3 / 3 MET A 201
GLU A 351
ARG A 187
 None
 1.11A 5tjzA-3ut3A:
undetectable		 5tjzA-3ut3A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		3 / 3 HIS A  10
SER A  13
ARG A 363
 None
 0.95A 5u63A-3ut3A:
undetectable		 5u63A-3ut3A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 7 PHE A 117
ARG A 118
ALA A  44
GLN A  47
 None
 1.27A 6b89A-3ut3A:
undetectable		 6b89A-3ut3A:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		3 / 3 PRO A 180
SER A 182
SER A 183
 None
 0.55A 6bpyA-3ut3A:
undetectable		 6bpyA-3ut3A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		4 / 5 VAL A  42
LEU A 286
VAL A  23
LEU A 293
 None
 0.95A 6bqgA-3ut3A:
undetectable		 6bqgA-3ut3A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EUQ_A_DXCA502_0
(MULTIDRUG
TRANSPORTER MDFA)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		5 / 11 MET A 295
LEU A 290
GLY A 153
LEU A  43
GLN A 322
 None
 1.43A 6euqA-3ut3A:
undetectable		 6euqA-3ut3A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens) 		5 / 11 ILE A  66
LEU A  48
THR A 307
MET A 298
THR A  54
 None
 1.39A 6hupA-3ut3A:
undetectable
6hupB-3ut3A:
undetectable		 6hupA-3ut3A:
13.98
6hupB-3ut3A:
12.83