SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3utn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 3utn THIOSULFATE
SULFURTRANSFERASE
TUM1
(Saccharomyces
cerevisiae) 		4 / 6 ASP X 284
GLY X 285
PRO X  69
SER X  66
 None
 0.68A 1n4fA-3utnX:
undetectable		 1n4fA-3utnX:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 3utn THIOSULFATE
SULFURTRANSFERASE
TUM1
(Saccharomyces
cerevisiae) 		4 / 6 LEU X  85
SER X  83
ASP X  80
ASP X  79
 DMS  X 409 (-4.0A)
None
None
None
 1.22A 2j2pE-3utnX:
undetectable
2j2pF-3utnX:
undetectable		 2j2pE-3utnX:
19.69
2j2pF-3utnX:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3utn THIOSULFATE
SULFURTRANSFERASE
TUM1
(Saccharomyces
cerevisiae) 		4 / 7 ALA X 271
LEU X 238
ALA X 241
PHE X 245
 None
 0.80A 2vcvL-3utnX:
undetectable		 2vcvL-3utnX:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_2
(PHOSPHOLIPASE A2)		 3utn THIOSULFATE
SULFURTRANSFERASE
TUM1
(Saccharomyces
cerevisiae) 		4 / 5 ILE X 299
SER X 205
PRO X 204
PRO X 197
 None
 1.25A 3bjwC-3utnX:
undetectable		 3bjwC-3utnX:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 3utn THIOSULFATE
SULFURTRANSFERASE
TUM1
(Saccharomyces
cerevisiae) 		4 / 5 LEU X 282
ASP X 284
ILE X 162
GLY X 262
 None
 0.95A 3bufA-3utnX:
undetectable		 3bufA-3utnX:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_A_SRYA403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3utn THIOSULFATE
SULFURTRANSFERASE
TUM1
(Saccharomyces
cerevisiae) 		4 / 8 ASP X 136
ASP X  39
ASP X  57
TYR X  96
 None
 1.23A 3havA-3utnX:
undetectable		 3havA-3utnX:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 3utn THIOSULFATE
SULFURTRANSFERASE
TUM1
(Saccharomyces
cerevisiae) 		4 / 6 LEU X 292
SER X 294
ILE X 203
PHE X 192
 None
 0.87A 3ko0B-3utnX:
undetectable		 3ko0B-3utnX:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 3utn THIOSULFATE
SULFURTRANSFERASE
TUM1
(Saccharomyces
cerevisiae) 		4 / 6 LEU X 292
SER X 294
ILE X 203
PHE X 192
 None
 0.79A 3ko0S-3utnX:
undetectable		 3ko0S-3utnX:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA302_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 3utn THIOSULFATE
SULFURTRANSFERASE
TUM1
(Saccharomyces
cerevisiae) 		4 / 6 LEU X 189
GLU X 193
ARG X 303
HIS X 207
 None
 1.46A 3ltwA-3utnX:
undetectable		 3ltwA-3utnX:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3utn THIOSULFATE
SULFURTRANSFERASE
TUM1
(Saccharomyces
cerevisiae) 		4 / 5 SER X 154
ASP X 159
ASP X 164
ILE X 162
 None
DMS  X 405 (-3.1A)
None
None
 1.32A 3uj7B-3utnX:
undetectable		 3uj7B-3utnX:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3utn THIOSULFATE
SULFURTRANSFERASE
TUM1
(Saccharomyces
cerevisiae) 		3 / 3 ASP X  90
LYS X  89
ASP X  91
 None
 0.86A 4a7tA-3utnX:
undetectable		 4a7tA-3utnX:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 3utn THIOSULFATE
SULFURTRANSFERASE
TUM1
(Saccharomyces
cerevisiae) 		5 / 10 VAL X  27
LEU X  93
VAL X  95
THR X 110
VAL X 119
 None
None
None
None
DMS  X 401 (-4.1A)
 0.93A 4e3hA-3utnX:
undetectable		 4e3hA-3utnX:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 3utn THIOSULFATE
SULFURTRANSFERASE
TUM1
(Saccharomyces
cerevisiae) 		4 / 7 PHE X  56
VAL X  95
PHE X  78
GLY X 112
 None
 0.98A 4ejjB-3utnX:
undetectable		 4ejjB-3utnX:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1N_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3utn THIOSULFATE
SULFURTRANSFERASE
TUM1
(Saccharomyces
cerevisiae) 		5 / 11 ILE X  58
ALA X  60
LEU X  85
PHE X  56
LEU X 111
 None
DMS  X 409 (-3.2A)
DMS  X 409 (-4.0A)
None
None
 1.25A 4i1nA-3utnX:
undetectable		 4i1nA-3utnX:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 3utn THIOSULFATE
SULFURTRANSFERASE
TUM1
(Saccharomyces
cerevisiae) 		4 / 6 PHE X 102
LEU X  33
HIS X  70
THR X 261
 None
 1.16A 4paeA-3utnX:
undetectable		 4paeA-3utnX:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 3utn THIOSULFATE
SULFURTRANSFERASE
TUM1
(Saccharomyces
cerevisiae) 		3 / 3 GLY X 175
GLN X 170
LYS X 179
 None
 0.99A 5imsB-3utnX:
undetectable		 5imsB-3utnX:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 3utn THIOSULFATE
SULFURTRANSFERASE
TUM1
(Saccharomyces
cerevisiae) 		4 / 7 ARG X 281
ALA X 183
ILE X 268
LEU X 272
 None
 0.95A 5te8A-3utnX:
undetectable		 5te8A-3utnX:
21.51