SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uuf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		4 / 6 TYR A 285
HIS A 170
GLU A 275
VAL A 230
 None
 1.40A 1q13A-3uufA:
undetectable		 1q13A-3uufA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		4 / 8 TYR A 196
PHE A 198
ALA A  95
LEU A  47
 None
 1.15A 1x8vA-3uufA:
undetectable		 1x8vA-3uufA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		5 / 12 VAL A  84
VAL A 153
VAL A 165
GLY A 169
TYR A 128
 None
 1.12A 2cbrA-3uufA:
undetectable		 2cbrA-3uufA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		4 / 6 GLY A 226
TYR A 260
ASP A 280
ASN A 225
 None
None
NAG  A 501 (-3.8A)
None
 1.14A 2g72A-3uufA:
undetectable		 2g72A-3uufA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		4 / 6 TYR A 260
GLY A 226
ASP A 280
ASN A 225
 None
None
NAG  A 501 (-3.8A)
None
 1.16A 2g72A-3uufA:
undetectable		 2g72A-3uufA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		4 / 7 GLN A 139
LEU A 179
ASP A 183
LEU A 186
 None
 0.93A 2qqcB-3uufA:
undetectable
2qqcC-3uufA:
undetectable		 2qqcB-3uufA:
18.37
2qqcC-3uufA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		4 / 7 LEU A 179
ASP A 183
LEU A 186
GLN A 139
 None
 0.89A 2qqcA-3uufA:
undetectable
2qqcF-3uufA:
undetectable		 2qqcA-3uufA:
12.74
2qqcF-3uufA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_E_AG2E671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		4 / 7 GLN A 139
LEU A 179
ASP A 183
LEU A 186
 None
 0.91A 2qqcD-3uufA:
undetectable
2qqcE-3uufA:
undetectable		 2qqcD-3uufA:
18.37
2qqcE-3uufA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		4 / 7 LEU A 179
ASP A 183
LEU A 186
GLN A 139
 None
 0.92A 2qqcG-3uufA:
undetectable
2qqcJ-3uufA:
undetectable		 2qqcG-3uufA:
12.74
2qqcJ-3uufA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		4 / 7 LEU A 179
ASP A 183
LEU A 186
GLN A 139
 None
 0.93A 2qqcI-3uufA:
undetectable
2qqcL-3uufA:
undetectable		 2qqcI-3uufA:
12.74
2qqcL-3uufA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_K_AG2K671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		4 / 8 GLN A 139
LEU A 179
ASP A 183
LEU A 186
 None
 0.89A 2qqcH-3uufA:
undetectable
2qqcK-3uufA:
undetectable		 2qqcH-3uufA:
18.37
2qqcK-3uufA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		5 / 12 ILE A 168
VAL A 167
GLY A 173
ALA A  97
LEU A 179
 None
 0.96A 3mb5A-3uufA:
undetectable		 3mb5A-3uufA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		5 / 12 SER A 256
PRO A 251
GLY A 252
LEU A 259
ASP A 245
 None
None
NAG  A 501 ( 4.1A)
None
None
 1.40A 3r24A-3uufA:
undetectable		 3r24A-3uufA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		3 / 3 LYS A  27
SER A 244
GLN A 263
 None
 1.38A 3si7A-3uufA:
undetectable		 3si7A-3uufA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		5 / 12 VAL A 230
HIS A 281
ASP A 228
GLY A 100
SER A 171
 None
 0.92A 3sufB-3uufA:
undetectable		 3sufB-3uufA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		5 / 12 ASP A 228
HIS A 170
PHE A 198
HIS A 281
GLY A 100
 None
 1.31A 4bz6A-3uufA:
undetectable
4bz6B-3uufA:
undetectable		 4bz6A-3uufA:
20.61
4bz6B-3uufA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		3 / 3 ASP A  33
GLY A 262
ASP A 245
 MAN  A 504 (-4.3A)
None
None
 0.69A 4xdtA-3uufA:
undetectable		 4xdtA-3uufA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		4 / 6 SER A 171
HIS A 281
PRO A 231
LEU A 106
 None
 1.33A 5dzka-3uufA:
2.3
5dzko-3uufA:
undetectable		 5dzka-3uufA:
22.57
5dzko-3uufA:
1.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		5 / 12 GLY A 173
HIS A 170
VAL A  52
ILE A 184
ALA A 181
 None
 1.04A 5n0sA-3uufA:
undetectable		 5n0sA-3uufA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		5 / 12 GLY A 173
HIS A 170
VAL A  52
ILE A 184
ALA A 181
 None
 1.01A 5n0tA-3uufA:
undetectable		 5n0tA-3uufA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		5 / 12 GLY A 173
HIS A 170
VAL A  52
ILE A 184
ALA A 181
 None
 1.02A 5n0wB-3uufA:
undetectable		 5n0wB-3uufA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)
(Malassezia
globosa) 		5 / 12 GLY A 173
HIS A 170
VAL A  52
ILE A 184
ALA A 181
 None
 1.03A 5n4iA-3uufA:
undetectable		 5n4iA-3uufA:
22.51