SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uv0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 3uv0 MUTATOR 2, ISOFORM B
(Drosophila
melanogaster) 		5 / 12 LEU A  96
LEU A  87
VAL A  73
ALA A  44
ALA A  58
 None
 1.05A 1n5xA-3uv0A:
undetectable		 1n5xA-3uv0A:
6.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 3uv0 MUTATOR 2, ISOFORM B
(Drosophila
melanogaster) 		5 / 12 LEU A  96
LEU A  87
VAL A  73
ALA A  44
ALA A  58
 None
 1.05A 1n5xB-3uv0A:
undetectable		 1n5xB-3uv0A:
6.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3uv0 MUTATOR 2, ISOFORM B
(Drosophila
melanogaster) 		4 / 8 ILE A  24
PHE A  89
ARG A  55
LEU A  16
 None
 0.88A 2eijN-3uv0A:
undetectable
2eijW-3uv0A:
undetectable		 2eijN-3uv0A:
10.43
2eijW-3uv0A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3uv0 MUTATOR 2, ISOFORM B
(Drosophila
melanogaster) 		4 / 8 ILE A  24
PHE A  89
ARG A  55
LEU A  16
 None
 0.88A 2eikN-3uv0A:
undetectable
2eikW-3uv0A:
undetectable		 2eikN-3uv0A:
10.43
2eikW-3uv0A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3uv0 MUTATOR 2, ISOFORM B
(Drosophila
melanogaster) 		4 / 8 ILE A  24
PHE A  89
ARG A  55
LEU A  16
 None
 0.86A 2eilN-3uv0A:
undetectable
2eilW-3uv0A:
undetectable		 2eilN-3uv0A:
10.43
2eilW-3uv0A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3uv0 MUTATOR 2, ISOFORM B
(Drosophila
melanogaster) 		4 / 8 ILE A  24
PHE A  89
ARG A  55
LEU A  16
 None
 0.90A 3ag3N-3uv0A:
undetectable
3ag3W-3uv0A:
undetectable		 3ag3N-3uv0A:
10.43
3ag3W-3uv0A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3uv0 MUTATOR 2, ISOFORM B
(Drosophila
melanogaster) 		4 / 8 ILE A  24
PHE A  89
ARG A  55
LEU A  16
 None
 0.88A 3asnN-3uv0A:
undetectable
3asnW-3uv0A:
undetectable		 3asnN-3uv0A:
10.43
3asnW-3uv0A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3uv0 MUTATOR 2, ISOFORM B
(Drosophila
melanogaster) 		4 / 7 ASN A  91
GLU A  37
GLU A  40
ARG A  26
 None
 1.09A 4mi4B-3uv0A:
undetectable
4mi4C-3uv0A:
undetectable		 4mi4B-3uv0A:
26.54
4mi4C-3uv0A:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3uv0 MUTATOR 2, ISOFORM B
(Drosophila
melanogaster) 		4 / 8 ASN A  91
GLU A  37
GLU A  40
ARG A  26
 None
 1.09A 4mj8B-3uv0A:
undetectable
4mj8C-3uv0A:
undetectable		 4mj8B-3uv0A:
26.54
4mj8C-3uv0A:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3uv0 MUTATOR 2, ISOFORM B
(Drosophila
melanogaster) 		4 / 7 ILE A  24
PHE A  89
ARG A  55
LEU A  16
 None
 0.81A 5b1bN-3uv0A:
undetectable
5b1bW-3uv0A:
undetectable		 5b1bN-3uv0A:
10.43
5b1bW-3uv0A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3uv0 MUTATOR 2, ISOFORM B
(Drosophila
melanogaster) 		4 / 7 ILE A  24
PHE A  89
ARG A  55
LEU A  16
 None
 0.90A 5b3sN-3uv0A:
undetectable
5b3sW-3uv0A:
undetectable		 5b3sN-3uv0A:
10.43
5b3sW-3uv0A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 3uv0 MUTATOR 2, ISOFORM B
(Drosophila
melanogaster) 		5 / 12 LEU A  16
LEU A  96
ILE A  24
ALA A  94
LEU A  11
 None
 0.98A 5og9B-3uv0A:
undetectable		 5og9B-3uv0A:
14.59