SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uv1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 3uv1 DER F 7 ALLERGEN
(Dermatophagoides
farinae) 		4 / 8 LYS A 190
GLU A 194
ALA A 186
THR A 182
 None
 0.93A 1ie4B-3uv1A:
undetectable
1ie4D-3uv1A:
undetectable		 1ie4B-3uv1A:
20.40
1ie4D-3uv1A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 3uv1 DER F 7 ALLERGEN
(Dermatophagoides
farinae) 		4 / 6 MET A 181
VAL A 184
LEU A 185
PHE A 189
 None
 0.93A 1x8vA-3uv1A:
undetectable		 1x8vA-3uv1A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 3uv1 DER F 7 ALLERGEN
(Dermatophagoides
farinae) 		5 / 12 LEU A 193
VAL A  75
ALA A  73
SER A 126
LEU A 127
 None
 1.06A 2c12C-3uv1A:
undetectable		 2c12C-3uv1A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3uv1 DER F 7 ALLERGEN
(Dermatophagoides
farinae) 		4 / 6 ARG A 178
MET A 181
THR A 182
LEU A 185
 None
 0.77A 3ag1N-3uv1A:
undetectable
3ag1W-3uv1A:
undetectable		 3ag1N-3uv1A:
17.05
3ag1W-3uv1A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3uv1 DER F 7 ALLERGEN
(Dermatophagoides
farinae) 		5 / 12 ILE A 135
ALA A  19
LEU A 193
LEU A 125
LEU A  86
 None
 0.93A 3uvvA-3uv1A:
undetectable		 3uvvA-3uv1A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3uv1 DER F 7 ALLERGEN
(Dermatophagoides
farinae) 		5 / 12 ASP A  17
ILE A  88
SER A 139
MET A 137
LEU A 193
 None
 1.29A 4a84A-3uv1A:
undetectable		 4a84A-3uv1A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 3uv1 DER F 7 ALLERGEN
(Dermatophagoides
farinae) 		5 / 11 ILE A  29
ASP A  30
GLY A  63
VAL A 123
GLY A  89
 None
 0.76A 4ac9B-3uv1A:
undetectable
4ac9C-3uv1A:
undetectable		 4ac9B-3uv1A:
18.49
4ac9C-3uv1A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3uv1 DER F 7 ALLERGEN
(Dermatophagoides
farinae) 		4 / 8 ILE A  29
ASP A  30
VAL A 123
GLY A  89
 None
 0.81A 4acaC-3uv1A:
undetectable		 4acaC-3uv1A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3uv1 DER F 7 ALLERGEN
(Dermatophagoides
farinae) 		4 / 8 ILE A  29
ASP A  30
VAL A 123
GLY A  89
 None
 0.83A 4acbC-3uv1A:
undetectable		 4acbC-3uv1A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)		 3uv1 DER F 7 ALLERGEN
(Dermatophagoides
farinae) 		5 / 11 HIS A 151
ILE A 152
LEU A 105
GLY A 163
PHE A 162
 None
 1.31A 4foxF-3uv1A:
undetectable		 4foxF-3uv1A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3uv1 DER F 7 ALLERGEN
(Dermatophagoides
farinae) 		4 / 5 ARG A 178
MET A 181
THR A 182
LEU A 185
 None
 1.09A 5x19J-3uv1A:
undetectable		 5x19J-3uv1A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3uv1 DER F 7 ALLERGEN
(Dermatophagoides
farinae) 		4 / 5 ARG A 178
MET A 181
THR A 182
LEU A 185
 None
 1.12A 5x1bJ-3uv1A:
undetectable		 5x1bJ-3uv1A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3uv1 DER F 7 ALLERGEN
(Dermatophagoides
farinae) 		4 / 5 ARG A 178
MET A 181
THR A 182
LEU A 185
 None
 0.77A 6nknJ-3uv1A:
undetectable		 6nknJ-3uv1A:
20.67