SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uv9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)
3uv9 TRIPARTITE
MOTIF-CONTAINING
PROTEIN 5

(Macaca
mulatta)
4 / 6 ASN A 308
ILE A 315
VAL A 322
ALA A 313
None
0.98A 2j5mA-3uv9A:
undetectable
2j5mA-3uv9A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)
3uv9 TRIPARTITE
MOTIF-CONTAINING
PROTEIN 5

(Macaca
mulatta)
4 / 7 GLN A 398
TYR A 389
GLN A 393
GLU A 392
None
1.07A 3l2vA-3uv9A:
undetectable
3l2vA-3uv9A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
3uv9 TRIPARTITE
MOTIF-CONTAINING
PROTEIN 5

(Macaca
mulatta)
4 / 7 GLU A 395
GLU A 392
TYR A 480
VAL A 453
None
1.04A 4a97D-3uv9A:
undetectable
4a97D-3uv9A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_A_SAMA1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)
3uv9 TRIPARTITE
MOTIF-CONTAINING
PROTEIN 5

(Macaca
mulatta)
5 / 12 GLY A 378
TYR A 364
GLU A 392
ASN A 482
TYR A 397
None
1.48A 4ymgA-3uv9A:
undetectable
4ymgA-3uv9A:
22.22