SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uvf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_A_DXCA801_0
(STEROID
DELTA-ISOMERASE)		 3uvf INTRON-ENCODED DNA
ENDONUCLEASE I-HJEMI
(Trichoderma
reesei) 		5 / 12 TYR A 256
GLY A 151
VAL A 214
LEU A 187
ALA A 221
 None
 1.25A 1e3vA-3uvfA:
undetectable		 1e3vA-3uvfA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4004_1
(SERUM ALBUMIN)		 3uvf INTRON-ENCODED DNA
ENDONUCLEASE I-HJEMI
(Trichoderma
reesei) 		4 / 4 VAL A 214
PHE A 189
SER A 210
VAL A 211
 None
 1.43A 1e7cA-3uvfA:
undetectable		 1e7cA-3uvfA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 3uvf INTRON-ENCODED DNA
ENDONUCLEASE I-HJEMI
(Trichoderma
reesei) 		4 / 5 LEU A  53
GLY A  56
ILE A  46
ILE A  49
 None
 0.82A 2q9rA-3uvfA:
undetectable		 2q9rA-3uvfA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 3uvf INTRON-ENCODED DNA
ENDONUCLEASE I-HJEMI
(Trichoderma
reesei) 		5 / 12 ILE A 171
ILE A 147
PHE A 169
ILE A 134
VAL A 223
 None
 1.05A 2ygoA-3uvfA:
undetectable		 2ygoA-3uvfA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 3uvf INTRON-ENCODED DNA
ENDONUCLEASE I-HJEMI
(Trichoderma
reesei) 		5 / 12 PHE A  87
GLU A 150
GLY A  17
ILE A  36
GLY A  13
 None
CA  A 303 ( 3.2A)
CA  A 302 ( 3.6A)
None
None
 1.09A 3ps9A-3uvfA:
undetectable		 3ps9A-3uvfA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 3uvf INTRON-ENCODED DNA
ENDONUCLEASE I-HJEMI
(Trichoderma
reesei) 		5 / 12 PHE A  87
GLU A 150
GLY A  17
PHE A  21
ILE A  36
 None
CA  A 303 ( 3.2A)
CA  A 302 ( 3.6A)
None
None
 1.17A 3ps9A-3uvfA:
undetectable		 3ps9A-3uvfA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 3uvf INTRON-ENCODED DNA
ENDONUCLEASE I-HJEMI
(Trichoderma
reesei) 		5 / 12 GLY A 151
LEU A 143
ASN A 213
PHE A 169
ILE A 218
 None
 0.91A 4pb1A-3uvfA:
undetectable		 4pb1A-3uvfA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3uvf INTRON-ENCODED DNA
ENDONUCLEASE I-HJEMI
(Trichoderma
reesei) 		4 / 5 LEU A 225
GLY A 227
ASP A  18
ILE A  36
 None
None
CA  A 301 ( 2.6A)
None
 0.93A 5ik1A-3uvfA:
undetectable		 5ik1A-3uvfA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3uvf INTRON-ENCODED DNA
ENDONUCLEASE I-HJEMI
(Trichoderma
reesei) 		3 / 3 GLU A 119
TYR A 120
ARG A 102
 None
 0.85A 5uunA-3uvfA:
2.3		 5uunA-3uvfA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3uvf INTRON-ENCODED DNA
ENDONUCLEASE I-HJEMI
(Trichoderma
reesei) 		3 / 3 GLU A 119
TYR A 120
ARG A 102
 None
 0.76A 5uunB-3uvfA:
undetectable		 5uunB-3uvfA:
22.98