SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uw0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 3uw0 PECTINESTERASE
(Yersinia
enterocolitica) 		4 / 7 ARG A  75
VAL A  78
SER A  76
ASP A  54
 None
 1.28A 1hwiC-3uw0A:
undetectable		 1hwiC-3uw0A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 3uw0 PECTINESTERASE
(Yersinia
enterocolitica) 		4 / 7 ARG A  75
VAL A  78
SER A  76
ASP A  54
 None
 1.28A 1hwiD-3uw0A:
undetectable		 1hwiD-3uw0A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_B_EV1B1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 3uw0 PECTINESTERASE
(Yersinia
enterocolitica) 		4 / 8 LEU A 158
VAL A 170
ILE A 194
PHE A 189
 None
 0.92A 2weyB-3uw0A:
undetectable		 2weyB-3uw0A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 3uw0 PECTINESTERASE
(Yersinia
enterocolitica) 		4 / 7 VAL A 170
ARG A  85
GLY A  91
VAL A 114
 None
 0.89A 2y05A-3uw0A:
undetectable
2y05B-3uw0A:
undetectable		 2y05A-3uw0A:
22.65
2y05B-3uw0A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZQ9_A_CLSA11_1
(BETA-LACTAMASE
TOHO-1)		 3uw0 PECTINESTERASE
(Yersinia
enterocolitica) 		4 / 4 GLU A 173
ARG A 129
ASN A 130
ASP A 131
 None
 1.09A 2zq9A-3uw0A:
undetectable		 2zq9A-3uw0A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_0
(UNCHARACTERIZED
PROTEIN PH0793)		 3uw0 PECTINESTERASE
(Yersinia
enterocolitica) 		5 / 12 ARG A 219
GLY A 196
HIS A 197
THR A 178
PHE A 288
 None
 1.49A 3a25A-3uw0A:
undetectable		 3a25A-3uw0A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)		 3uw0 PECTINESTERASE
(Yersinia
enterocolitica) 		3 / 3 TYR A 298
ASP A 199
ASP A 301
 None
 0.71A 3r24A-3uw0A:
undetectable		 3r24A-3uw0A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 3uw0 PECTINESTERASE
(Yersinia
enterocolitica) 		5 / 11 LEU A 249
ILE A 194
ILE A 243
ILE A 229
ILE A 214
 None
 0.88A 3s53B-3uw0A:
undetectable		 3s53B-3uw0A:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_A_CLMA221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3uw0 PECTINESTERASE
(Yersinia
enterocolitica) 		5 / 9 PHE A 167
PHE A 209
LEU A 157
PHE A 202
VAL A 154
 None
 1.44A 3u9fA-3uw0A:
0.0		 3u9fA-3uw0A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3uw0 PECTINESTERASE
(Yersinia
enterocolitica) 		3 / 3 SER A 233
ASP A 177
ASP A 150
 None
 0.68A 3uj7A-3uw0A:
undetectable		 3uj7A-3uw0A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3uw0 PECTINESTERASE
(Yersinia
enterocolitica) 		3 / 3 SER A 233
ASP A 177
ASP A 150
 None
 0.62A 4mwzA-3uw0A:
undetectable		 4mwzA-3uw0A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 3uw0 PECTINESTERASE
(Yersinia
enterocolitica) 		6 / 12 LEU A 179
GLY A 203
ILE A 229
ILE A 243
ILE A 194
ILE A 201
 None
 1.41A 5e5jB-3uw0A:
undetectable		 5e5jB-3uw0A:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3uw0 PECTINESTERASE
(Yersinia
enterocolitica) 		4 / 6 PHE A 202
PRO A 232
THR A 207
ILE A 201
 None
 1.31A 5ih0A-3uw0A:
undetectable		 5ih0A-3uw0A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UL4_A_SAMA803_0
(OXSB PROTEIN)		 3uw0 PECTINESTERASE
(Yersinia
enterocolitica) 		5 / 12 ARG A  85
GLY A  87
GLY A  65
GLU A  69
LEU A  71
 None
 1.02A 5ul4A-3uw0A:
undetectable		 5ul4A-3uw0A:
19.06