SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uw5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYK_B_IMNB300_1
(LACTOYLGLUTATHIONE
LYASE)		 3uw5 BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 7,
BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 4
(Homo
sapiens) 		5 / 12 ALA A 110
PHE A 113
LEU A 131
GLY A 159
LYS A 158
 None
 1.09A 4kykA-3uw5A:
undetectable
4kykB-3uw5A:
undetectable		 4kykA-3uw5A:
18.38
4kykB-3uw5A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3uw5 BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 7,
BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 4
(Homo
sapiens) 		4 / 7 GLU A  88
SER A  86
GLY A  85
ALA A 109
 None
 0.99A 5e26A-3uw5A:
undetectable
5e26B-3uw5A:
undetectable		 5e26A-3uw5A:
16.67
5e26B-3uw5A:
16.67