SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uwa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KEC_B_HAEB271_1 (COLLAGENASE 3)	3uwa	RIIA-RIIB MEMBRANE-ASSOCIATED PROTEIN (Synechococcus phage S-SSM7)	3 / 3	HIS A 134 GLU A 135 HIS A 138	ZN A 200 (-3.3A) ZN A 200 ( 3.9A) ZN A 200 (-3.3A)	0.22A	3kecB-3uwaA: undetectable	3kecB-3uwaA: 23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AZV_A_SAMA1474_0 (WBDD)	3uwa	RIIA-RIIB MEMBRANE-ASSOCIATED PROTEIN (Synechococcus phage S-SSM7)	5 / 12	ILE A 136 PHE A 112 ILE A 57 VAL A 59 HIS A 71	None None None None MRD A 201 (-4.2A)	0.99A	4azvA-3uwaA: undetectable	4azvA-3uwaA: 15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ICX_E_SC2E1_1 (CETUXIMAB FAB LIGHT CHAIN MEDITOPE)	3uwa	RIIA-RIIB MEMBRANE-ASSOCIATED PROTEIN (Synechococcus phage S-SSM7)	3 / 3	VAL A 58 GLN A 32 CYH A 34	None	0.76A	5icxA-3uwaA: undetectable 5icxE-3uwaA: undetectable	5icxA-3uwaA: 20.91 5icxE-3uwaA: 7.44