SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ux9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
6 / 12 TYR B  39
GLN B  92
PHE B 103
VAL B 171
ALA B 231
TRP B 243
None
0.74A 1h8sA-3ux9B:
27.3
1h8sA-3ux9B:
48.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 VAL B 111
ARG B  64
VAL B  20
GLU B  86
None
1.12A 1zzrA-3ux9B:
undetectable
1zzrB-3ux9B:
undetectable
1zzrA-3ux9B:
21.28
1zzrB-3ux9B:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 GLU B  86
VAL B 111
ARG B  64
VAL B  20
None
1.14A 1zzrA-3ux9B:
undetectable
1zzrB-3ux9B:
undetectable
1zzrA-3ux9B:
21.28
1zzrB-3ux9B:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 VAL B 111
ARG B  64
VAL B  20
GLU B  86
None
1.12A 1zzuA-3ux9B:
undetectable
1zzuB-3ux9B:
undetectable
1zzuA-3ux9B:
21.28
1zzuB-3ux9B:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 GLU B  86
VAL B 111
ARG B  64
VAL B  20
None
1.11A 1zzuA-3ux9B:
undetectable
1zzuB-3ux9B:
undetectable
1zzuA-3ux9B:
21.28
1zzuB-3ux9B:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0D_A_ERYA1498_0
(CYTOCHROME P450 3A4)
3ux9 INTERFERON
ALPHA-1/13

(Homo
sapiens)
5 / 12 SER A 151
ILE A 148
PHE A  36
ALA A 119
GLU A  59
None
0.76A 2j0dA-3ux9A:
undetectable
2j0dA-3ux9A:
16.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OLD_B_IPHB2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 TYR B  39
PRO B  47
TYR B  90
TYR B 229
None
0.73A 2oldA-3ux9B:
21.2
2oldB-3ux9B:
21.3
2oldA-3ux9B:
38.26
2oldB-3ux9B:
38.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 VAL B 111
ARG B  64
VAL B  20
GLU B  86
None
1.15A 3dqrA-3ux9B:
undetectable
3dqrB-3ux9B:
undetectable
3dqrA-3ux9B:
21.18
3dqrB-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 GLU B  86
VAL B 111
ARG B  64
VAL B  20
None
1.17A 3dqrA-3ux9B:
undetectable
3dqrB-3ux9B:
undetectable
3dqrA-3ux9B:
21.18
3dqrB-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)
3ux9 INTERFERON
ALPHA-1/13
SCFV ANTIBODY

(Homo
sapiens)
5 / 10 LEU B 213
ILE B 185
SER A  27
SER B 165
GLY B 187
None
1.46A 3ik6B-3ux9B:
undetectable
3ik6E-3ux9B:
undetectable
3ik6B-3ux9B:
21.33
3ik6E-3ux9B:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 VAL B 111
ARG B  64
VAL B  20
GLU B  86
None
1.07A 3jx2A-3ux9B:
undetectable
3jx2B-3ux9B:
undetectable
3jx2A-3ux9B:
21.18
3jx2B-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 GLU B  86
VAL B 111
ARG B  64
VAL B  20
None
1.12A 3jx2A-3ux9B:
undetectable
3jx2B-3ux9B:
undetectable
3jx2A-3ux9B:
21.18
3jx2B-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 VAL B 111
ARG B  64
VAL B  20
GLU B  86
None
1.14A 3jx3A-3ux9B:
undetectable
3jx3B-3ux9B:
undetectable
3jx3A-3ux9B:
21.18
3jx3B-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 GLU B  86
VAL B 111
ARG B  64
VAL B  20
None
1.09A 3jx3A-3ux9B:
undetectable
3jx3B-3ux9B:
undetectable
3jx3A-3ux9B:
21.18
3jx3B-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 GLU B  86
VAL B 111
ARG B  64
VAL B  20
None
1.14A 3jx4A-3ux9B:
undetectable
3jx4B-3ux9B:
undetectable
3jx4A-3ux9B:
21.18
3jx4B-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 VAL B 111
ARG B  64
VAL B  20
GLU B  86
None
1.11A 3jx5A-3ux9B:
undetectable
3jx5B-3ux9B:
undetectable
3jx5A-3ux9B:
21.18
3jx5B-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 GLU B  86
VAL B 111
ARG B  64
VAL B  20
None
1.12A 3jx5A-3ux9B:
undetectable
3jx5B-3ux9B:
undetectable
3jx5A-3ux9B:
21.18
3jx5B-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 VAL B 111
ARG B  64
VAL B  20
GLU B  86
None
1.03A 3jx6A-3ux9B:
undetectable
3jx6B-3ux9B:
undetectable
3jx6A-3ux9B:
21.18
3jx6B-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 GLU B  86
VAL B 111
ARG B  64
VAL B  20
None
1.07A 3jx6A-3ux9B:
undetectable
3jx6B-3ux9B:
undetectable
3jx6A-3ux9B:
21.18
3jx6B-3ux9B:
21.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KDM_H_TESH226_1
(IMMUNOGLOBULIN HEAVY
CHAIN
IMMUNOGLOBULIN LIGHT
CHAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
5 / 9 SER B 169
TRP B 181
ALA B 184
TYR B 193
MET B 240
None
0.75A 3kdmH-3ux9B:
14.2
3kdmL-3ux9B:
21.4
3kdmH-3ux9B:
66.47
3kdmL-3ux9B:
39.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 VAL B 111
ARG B  64
VAL B  20
GLU B  86
None
1.05A 3nljA-3ux9B:
undetectable
3nljB-3ux9B:
undetectable
3nljA-3ux9B:
21.18
3nljB-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 GLU B  86
VAL B 111
ARG B  64
VAL B  20
None
1.06A 3nljA-3ux9B:
undetectable
3nljB-3ux9B:
undetectable
3nljA-3ux9B:
21.18
3nljB-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 VAL B 111
ARG B  64
VAL B  20
GLU B  86
None
1.08A 3nlpA-3ux9B:
undetectable
3nlpB-3ux9B:
undetectable
3nlpA-3ux9B:
21.18
3nlpB-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 GLU B  86
VAL B 111
ARG B  64
VAL B  20
None
1.11A 3nlpA-3ux9B:
undetectable
3nlpB-3ux9B:
undetectable
3nlpA-3ux9B:
21.18
3nlpB-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 8 VAL B 111
ARG B  64
VAL B  20
GLU B  86
None
1.07A 3nlqA-3ux9B:
undetectable
3nlqB-3ux9B:
undetectable
3nlqA-3ux9B:
21.18
3nlqB-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 GLU B  86
VAL B 111
ARG B  64
VAL B  20
None
1.13A 3nlqA-3ux9B:
undetectable
3nlqB-3ux9B:
undetectable
3nlqA-3ux9B:
21.18
3nlqB-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 VAL B 111
ARG B  64
VAL B  20
GLU B  86
None
1.08A 3nlrA-3ux9B:
undetectable
3nlrB-3ux9B:
undetectable
3nlrA-3ux9B:
21.18
3nlrB-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 8 GLU B  86
VAL B 111
ARG B  64
VAL B  20
None
1.11A 3nlrA-3ux9B:
undetectable
3nlrB-3ux9B:
undetectable
3nlrA-3ux9B:
21.18
3nlrB-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 VAL B 111
ARG B  64
VAL B  20
GLU B  86
None
1.12A 4cx3A-3ux9B:
undetectable
4cx3B-3ux9B:
undetectable
4cx3A-3ux9B:
21.18
4cx3B-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 GLU B  86
VAL B 111
ARG B  64
VAL B  20
None
1.11A 4cx3A-3ux9B:
undetectable
4cx3B-3ux9B:
undetectable
4cx3A-3ux9B:
21.18
4cx3B-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 VAL B 111
ARG B  64
VAL B  20
GLU B  86
None
1.14A 4cx4A-3ux9B:
undetectable
4cx4B-3ux9B:
undetectable
4cx4A-3ux9B:
21.18
4cx4B-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 GLU B  86
VAL B 111
ARG B  64
VAL B  20
None
1.11A 4cx4A-3ux9B:
undetectable
4cx4B-3ux9B:
undetectable
4cx4A-3ux9B:
21.18
4cx4B-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)
3ux9 INTERFERON
ALPHA-1/13

(Homo
sapiens)
4 / 5 GLU A 142
ARG A 145
PRO A  26
SER A  27
None
1.44A 4k17B-3ux9A:
undetectable
4k17B-3ux9A:
13.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ACL_A_SASA1111_1
(MCG)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
5 / 7 TYR B  35
SER B  37
TYR B  39
TYR B  52
PRO B  58
None
0.78A 5aclA-3ux9B:
21.1
5aclA-3ux9B:
31.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 GLU B  86
VAL B 111
ARG B  64
VAL B  20
None
1.07A 5addA-3ux9B:
undetectable
5addB-3ux9B:
undetectable
5addA-3ux9B:
21.18
5addB-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 GLU B  86
VAL B 111
ARG B  64
VAL B  20
None
1.06A 5adeA-3ux9B:
undetectable
5adeB-3ux9B:
undetectable
5adeA-3ux9B:
21.18
5adeB-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 VAL B 111
ARG B  64
VAL B  20
GLU B  86
None
1.10A 5g0pA-3ux9B:
undetectable
5g0pB-3ux9B:
undetectable
5g0pA-3ux9B:
21.18
5g0pB-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3ux9 SCFV ANTIBODY
(Homo
sapiens)
4 / 7 GLU B  86
VAL B 111
ARG B  64
VAL B  20
None
1.13A 5g0pA-3ux9B:
undetectable
5g0pB-3ux9B:
undetectable
5g0pA-3ux9B:
21.18
5g0pB-3ux9B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)
3ux9 INTERFERON
ALPHA-1/13

(Homo
sapiens)
3 / 3 LYS A  51
ASP A  44
ILE A 117
None
0.69A 5kc4E-3ux9A:
undetectable
5kc4E-3ux9A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)
3ux9 INTERFERON
ALPHA-1/13

(Homo
sapiens)
3 / 3 SER A 151
SER A 155
PHE A 124
None
0.90A 5mugA-3ux9A:
undetectable
5mugA-3ux9A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)
3ux9 INTERFERON
ALPHA-1/13

(Homo
sapiens)
5 / 12 SER A 151
TYR A 123
PHE A 124
ILE A 127
LEU A  67
None
1.21A 5zwrB-3ux9A:
undetectable
5zwrB-3ux9A:
18.55