SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uy4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		5 / 10 PHE A 135
VAL A 156
VAL A 143
TYR A  26
VAL A  27
 None
 1.21A 1fe2A-3uy4A:
undetectable		 1fe2A-3uy4A:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JZS_A_MRCA1301_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		5 / 11 HIS A  34
HIS A  37
GLY A 146
ASP A 149
ILE A 175
 AMP  A 301 ( 4.5A)
AMP  A 301 (-3.9A)
AMP  A 301 (-3.3A)
PAU  A 302 ( 3.7A)
AMP  A 301 (-4.2A)
 1.12A 1jzsA-3uy4A:
undetectable		 1jzsA-3uy4A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		3 / 3 ARG A 186
ARG A  72
ARG A 120
 PAU  A 302 (-3.2A)
None
PAU  A 302 (-3.1A)
 0.80A 1l7fA-3uy4A:
undetectable		 1l7fA-3uy4A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		3 / 3 ARG A 186
ARG A  72
ARG A 120
 PAU  A 302 (-3.2A)
None
PAU  A 302 (-3.1A)
 0.83A 1l7hA-3uy4A:
undetectable		 1l7hA-3uy4A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		5 / 11 HIS A  34
GLY A  36
HIS A  37
GLY A 146
ASP A 149
 AMP  A 301 ( 4.5A)
AMP  A 301 ( 3.9A)
AMP  A 301 (-3.9A)
AMP  A 301 (-3.3A)
PAU  A 302 ( 3.7A)
 1.03A 1pg2A-3uy4A:
3.6		 1pg2A-3uy4A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		5 / 9 ASP A 274
LEU A 181
VAL A 267
ILE A 236
ILE A 241
 None
 1.42A 1q6iA-3uy4A:
undetectable		 1q6iA-3uy4A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		5 / 12 HIS A  34
GLY A  36
HIS A  37
GLY A 146
ASP A 149
 AMP  A 301 ( 4.5A)
AMP  A 301 ( 3.9A)
AMP  A 301 (-3.9A)
AMP  A 301 (-3.3A)
PAU  A 302 ( 3.7A)
 0.95A 1qu2A-3uy4A:
4.5		 1qu2A-3uy4A:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		5 / 12 VAL A  52
HIS A  34
ARG A 186
ILE A 273
TYR A  70
 None
AMP  A 301 ( 4.5A)
PAU  A 302 (-3.2A)
None
None
 1.47A 1xvaA-3uy4A:
2.5		 1xvaA-3uy4A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_A_ADNA601_1
(METHIONYL-TRNA
SYNTHETASE)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		5 / 11 HIS A  34
GLY A  36
HIS A  37
GLY A 146
ASP A 149
 AMP  A 301 ( 4.5A)
AMP  A 301 ( 3.9A)
AMP  A 301 (-3.9A)
AMP  A 301 (-3.3A)
PAU  A 302 ( 3.7A)
 0.98A 2x1lA-3uy4A:
5.6		 2x1lA-3uy4A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_B_ADNB601_1
(METHIONYL-TRNA
SYNTHETASE)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		5 / 12 HIS A  34
GLY A  36
HIS A  37
GLY A 146
ASP A 149
 AMP  A 301 ( 4.5A)
AMP  A 301 ( 3.9A)
AMP  A 301 (-3.9A)
AMP  A 301 (-3.3A)
PAU  A 302 ( 3.7A)
 0.92A 2x1lB-3uy4A:
6.4		 2x1lB-3uy4A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_C_ADNC601_1
(METHIONYL-TRNA
SYNTHETASE)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		5 / 11 HIS A  34
GLY A  36
HIS A  37
GLY A 146
ASP A 149
 AMP  A 301 ( 4.5A)
AMP  A 301 ( 3.9A)
AMP  A 301 (-3.9A)
AMP  A 301 (-3.3A)
PAU  A 302 ( 3.7A)
 0.94A 2x1lC-3uy4A:
5.6		 2x1lC-3uy4A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		4 / 8 HIS A  37
TYR A 189
LEU A 272
SER A 185
 AMP  A 301 (-3.9A)
None
None
AMP  A 301 ( 4.9A)
 0.90A 3lm8B-3uy4A:
2.4
3lm8D-3uy4A:
undetectable		 3lm8B-3uy4A:
22.90
3lm8D-3uy4A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		4 / 5 LEU A 138
ILE A  91
PRO A  92
PHE A  55
 None
 1.23A 3s3vA-3uy4A:
undetectable		 3s3vA-3uy4A:
22.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		8 / 8 GLN A  60
ARG A 120
HIS A 123
VAL A 127
VAL A 130
ASP A 149
GLN A 152
ARG A 186
 PAU  A 302 (-2.9A)
PAU  A 302 (-3.1A)
PAU  A 302 (-4.5A)
PAU  A 302 (-3.9A)
None
PAU  A 302 ( 3.7A)
PAU  A 302 (-3.1A)
PAU  A 302 (-3.2A)
 0.04A 3uy4A-3uy4A:
49.0		 3uy4A-3uy4A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		3 / 3 ASN A 258
ASP A 245
ASN A 247
 None
 0.58A 4agaA-3uy4A:
undetectable		 4agaA-3uy4A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		3 / 3 SER A 185
TYR A  70
ASP A  77
 AMP  A 301 ( 4.9A)
None
None
 0.87A 4rp8C-3uy4A:
2.1		 4rp8C-3uy4A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		3 / 3 GLU A 209
ARG A 213
GLN A 147
 None
 0.88A 4rtbA-3uy4A:
undetectable		 4rtbA-3uy4A:
23.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		9 / 12 HIS A  34
GLY A  36
LEU A  40
GLN A  60
TYR A  70
VAL A 130
GLY A 146
LYS A 148
ASP A 149
 AMP  A 301 ( 4.5A)
AMP  A 301 ( 3.9A)
AMP  A 301 (-4.8A)
PAU  A 302 (-2.9A)
None
None
AMP  A 301 (-3.3A)
None
PAU  A 302 ( 3.7A)
 0.48A 5hg0A-3uy4A:
32.8		 5hg0A-3uy4A:
36.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		6 / 12 HIS A  37
GLY A  36
GLN A  60
TYR A  70
GLY A 146
ASP A 149
 AMP  A 301 (-3.9A)
AMP  A 301 ( 3.9A)
PAU  A 302 (-2.9A)
None
AMP  A 301 (-3.3A)
PAU  A 302 ( 3.7A)
 1.44A 5hg0A-3uy4A:
32.8		 5hg0A-3uy4A:
36.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		6 / 12 HIS A  34
GLY A  36
HIS A  37
LEU A  40
TYR A  70
VAL A 127
 AMP  A 301 ( 4.5A)
AMP  A 301 ( 3.9A)
AMP  A 301 (-3.9A)
AMP  A 301 (-4.8A)
None
PAU  A 302 (-3.9A)
 1.11A 5hg0B-3uy4A:
32.7		 5hg0B-3uy4A:
36.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		8 / 12 HIS A  34
GLY A  36
HIS A  37
LEU A  40
TYR A  70
VAL A 130
GLY A 146
ASP A 149
 AMP  A 301 ( 4.5A)
AMP  A 301 ( 3.9A)
AMP  A 301 (-3.9A)
AMP  A 301 (-4.8A)
None
None
AMP  A 301 (-3.3A)
PAU  A 302 ( 3.7A)
 0.23A 5hg0B-3uy4A:
32.7		 5hg0B-3uy4A:
36.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		8 / 12 HIS A  34
GLY A  36
LEU A  40
TYR A  70
VAL A 130
GLY A 146
LYS A 148
ASP A 149
 AMP  A 301 ( 4.5A)
AMP  A 301 ( 3.9A)
AMP  A 301 (-4.8A)
None
None
AMP  A 301 (-3.3A)
None
PAU  A 302 ( 3.7A)
 0.55A 5hg0B-3uy4A:
32.7		 5hg0B-3uy4A:
36.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		5 / 12 ILE A 175
ASP A 179
LEU A 181
GLY A 180
ASP A 149
 AMP  A 301 (-4.2A)
None
None
None
PAU  A 302 ( 3.7A)
 1.03A 5x66A-3uy4A:
undetectable
5x66B-3uy4A:
undetectable		 5x66A-3uy4A:
22.46
5x66B-3uy4A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		4 / 5 LEU A 272
VAL A 267
GLU A 194
LEU A 190
 None
 1.03A 5xooB-3uy4A:
undetectable		 5xooB-3uy4A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 3uy4 PANTOTHENATE
SYNTHETASE
(Campylobacter
jejuni) 		3 / 3 PHE A  61
ARG A 120
GLN A  60
 None
PAU  A 302 (-3.1A)
PAU  A 302 (-2.9A)
 1.18A 6g1pB-3uy4A:
undetectable		 6g1pB-3uy4A:
22.28