SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uyr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC2_0 (ACTINOMYCIN D)	3uyr	ANTIBODY FAB HEAVY CHAIN (Mus musculus)	4 / 4	THR H 121 PRO H 151 THR H 120 PRO H 122	None	1.34A	1dsdC-3uyrH: undetectable	1dsdC-3uyrH: 6.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC8_0 (ACTINOMYCIN D)	3uyr	ANTIBODY FAB HEAVY CHAIN (Mus musculus)	4 / 4	THR H 121 PRO H 151 THR H 120 PRO H 122	None	1.34A	1dsdC-3uyrH: undetectable	1dsdC-3uyrH: 6.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EM2_A_SALA501_1 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349)	3uyr	ANTIBODY FAB HEAVY CHAIN (Mus musculus)	4 / 5	TYR H 94 LEU H 81 LEU H 86 ARG H 67	None	1.23A	4em2A-3uyrH: undetectable	4em2A-3uyrH: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JHD_E_EDTE301_0 (BETA-2-MICROGLOBULIN TCRBETA CHAIN)	3uyr	ANTIBODY FAB HEAVY CHAIN (Mus musculus)	4 / 8	TYR H 149 SER H 153 THR H 112 PRO H 171	None	1.04A	5jhdE-3uyrH: 18.4 5jhdG-3uyrH: 5.5	5jhdE-3uyrH: 28.19 5jhdG-3uyrH: 14.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5MTH_A_ACTA302_0 (ANTIBODY FAB HEAVY CHAIN)	3uyr	ANTIBODY FAB HEAVY CHAIN (Mus musculus)	4 / 5	SER H 116 ALA H 118 PHE H 150 LEU H 174	None	0.18A	5mthA-3uyrH: 27.7	5mthA-3uyrH: 62.56

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DSD_C_DVAC2_0","ACTINOMYCIN D","3uyr","ANTIBODY FAB HEAVY CHAIN","Mus musculus",4,"THR H 121;PRO H 151;THR H 120;PRO H 122","None","1.34A","1dsdC-3uyrH:undetectable","1dsdC-3uyrH:6.43"],["1DSD_C_DVAC8_0","ACTINOMYCIN D","3uyr","ANTIBODY FAB HEAVY CHAIN","Mus musculus",4,"THR H 121;PRO H 151;THR H 120;PRO H 122","None","1.34A","1dsdC-3uyrH:undetectable","1dsdC-3uyrH:6.43"],["4EM2_A_SALA501_1","UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349","3uyr","ANTIBODY FAB HEAVY CHAIN","Mus musculus",4,"TYR H  94;LEU H  81;LEU H  86;ARG H  67","None","1.23A","4em2A-3uyrH:undetectable","4em2A-3uyrH:21.15"],["5JHD_E_EDTE301_0","BETA-2-MICROGLOBULIN;TCRBETA CHAIN","3uyr","ANTIBODY FAB HEAVY CHAIN","Mus musculus",4,"TYR H 149;SER H 153;THR H 112;PRO H 171","None","1.04A","5jhdE-3uyrH:18.4;5jhdG-3uyrH:5.5","5jhdE-3uyrH:28.19;5jhdG-3uyrH:14.80"],["5MTH_A_ACTA302_0","ANTIBODY FAB HEAVY CHAIN","3uyr","ANTIBODY FAB HEAVY CHAIN","Mus musculus",4,"SER H 116;ALA H 118;PHE H 150;LEU H 174","None","0.18A","5mthA-3uyrH:27.7","5mthA-3uyrH:62.56"]]