SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uyu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_B_VDYB6178_1
(VITAMIN D
HYDROXYLASE)		 3uyu ANTIFREEZE PROTEIN
(Leucosporidium
sp.
AY30) 		5 / 12 PRO A  97
THR A  96
LEU A 100
ILE A  87
VAL A 233
 None
 1.26A 3a51B-3uyuA:
undetectable		 3a51B-3uyuA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 3uyu ANTIFREEZE PROTEIN
(Leucosporidium
sp.
AY30) 		4 / 8 PHE A 191
LEU A 130
PHE A 154
LEU A 135
 None
 0.97A 3i45A-3uyuA:
undetectable		 3i45A-3uyuA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_2
(FIV PROTEASE)		 3uyu ANTIFREEZE PROTEIN
(Leucosporidium
sp.
AY30) 		5 / 10 VAL A 197
GLY A 207
ILE A 189
VAL A 146
LEU A 170
 None
 1.32A 3ogpB-3uyuA:
undetectable		 3ogpB-3uyuA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 3uyu ANTIFREEZE PROTEIN
(Leucosporidium
sp.
AY30) 		4 / 7 PHE A 191
GLY A 207
THR A 161
PHE A 154
 None
 0.98A 3vnsA-3uyuA:
undetectable		 3vnsA-3uyuA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 3uyu ANTIFREEZE PROTEIN
(Leucosporidium
sp.
AY30) 		5 / 12 GLY A 169
GLY A 194
VAL A 197
GLN A 192
SER A 145
 None
 1.22A 4f84A-3uyuA:
undetectable		 4f84A-3uyuA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 3uyu ANTIFREEZE PROTEIN
(Leucosporidium
sp.
AY30) 		5 / 11 ASP A  53
LEU A 100
LYS A  39
ILE A  42
ILE A  50
 None
 1.16A 5gpgA-3uyuA:
undetectable		 5gpgA-3uyuA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GSD_A_STRA401_0
(PROGESTERONE
5-BETA-REDUCTASE)		 3uyu ANTIFREEZE PROTEIN
(Leucosporidium
sp.
AY30) 		5 / 12 VAL A  83
PHE A  34
ILE A  54
VAL A  56
ILE A  42
 None
 1.49A 6gsdA-3uyuA:
undetectable		 6gsdA-3uyuA:
15.48