SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uyw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3uyw HEMAGGLUTININ
(Influenza
A
virus) 		4 / 4 SER A 127
TRP A 129
ASP A 244
ILE A 246
 None
 1.34A 2oxtD-3uywA:
0.0		 2oxtD-3uywA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 3uyw HEMAGGLUTININ
(Influenza
A
virus) 		4 / 4 ASN A  62
ALA A  64
GLY A  65
THR A  95
 None
 1.29A 4bboC-3uywA:
undetectable		 4bboC-3uywA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J03_A_FVSA603_1
(BIFUNCTIONAL EPOXIDE
HYDROLASE 2)		 3uyw HEMAGGLUTININ
(Influenza
A
virus) 		5 / 12 PHE A 101
LEU A 180
LEU A 182
TYR A 104
LEU A  58
 None
 1.29A 4j03A-3uywA:
undetectable		 4j03A-3uywA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3uyw HEMAGGLUTININ
(Influenza
A
virus) 		4 / 4 LEU A 180
TYR A 151
PRO A 257
ILE A 122
 None
 1.32A 5esgA-3uywA:
undetectable		 5esgA-3uywA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)		 3uyw HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 GLU A 121
ARG A 258
TYR A 259
 None
 0.66A 5trqB-3uywA:
undetectable		 5trqB-3uywA:
21.69