SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uz0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3uz0 STAGE II SPORULATION
PROTEIN Q
(Bacillus
subtilis) 		5 / 12 THR B 165
GLU B 158
GLY B 162
VAL B 155
VAL B 143
 None
 1.32A 1n2xA-3uz0B:
undetectable		 1n2xA-3uz0B:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 3uz0 STAGE II SPORULATION
PROTEIN Q
(Bacillus
subtilis) 		3 / 3 PRO B  82
PHE B 219
LYS B  78
 None
 1.23A 3bjwG-3uz0B:
undetectable		 3bjwG-3uz0B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 3uz0 STAGE III
SPORULATION PROTEIN
AH
(Bacillus
subtilis) 		3 / 3 GLU A 150
GLY A 153
THR A 154
 None
 0.55A 3iazA-3uz0A:
undetectable		 3iazA-3uz0A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 3uz0 STAGE III
SPORULATION PROTEIN
AH
(Bacillus
subtilis) 		4 / 5 ALA A 141
GLU A 137
GLU A 140
ALA A 133
 None
 1.43A 3r9tC-3uz0A:
undetectable		 3r9tC-3uz0A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3uz0 STAGE II SPORULATION
PROTEIN Q
STAGE III
SPORULATION PROTEIN
AH
(Bacillus
subtilis) 		5 / 12 ILE A 181
VAL A 210
LEU B 118
ALA A 201
LEU A 199
 None
 1.33A 4m11A-3uz0A:
undetectable		 4m11A-3uz0A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3uz0 STAGE II SPORULATION
PROTEIN Q
STAGE III
SPORULATION PROTEIN
AH
(Bacillus
subtilis) 		5 / 12 ILE A 181
VAL A 210
LEU B 118
ALA A 201
LEU A 199
 None
 1.32A 4m11C-3uz0A:
undetectable		 4m11C-3uz0A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 3uz0 STAGE III
SPORULATION PROTEIN
AH
(Bacillus
subtilis) 		5 / 12 VAL A 151
GLU A 152
ALA A 147
ARG A 117
LEU A 124
 None
 1.38A 5m54B-3uz0A:
undetectable		 5m54B-3uz0A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3uz0 STAGE III
SPORULATION PROTEIN
AH
(Bacillus
subtilis) 		4 / 6 LEU A 113
LYS A 156
GLU A 159
LEU A 171
 None
 1.17A 5xooA-3uz0A:
undetectable		 5xooA-3uz0A:
25.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IFT_A_SAMA301_1
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)		 3uz0 STAGE III
SPORULATION PROTEIN
AH
STAGE II SPORULATION
PROTEIN Q
(Bacillus
subtilis;
Bacillus
subtilis) 		4 / 5 GLN B 168
GLU B 206
ASP A 209
TYR B 195
 None
 1.49A 6iftA-3uz0B:
undetectable		 6iftA-3uz0B:
22.79