SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uzu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 9 LEU A  88
GLY A  48
VAL A  56
GLY A 116
ILE A  45
None
1.00A 1hpvA-3uzuA:
undetectable
1hpvA-3uzuA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 11 LEU A  88
GLY A  48
VAL A  56
GLY A 116
ILE A  45
None
0.99A 1hxwB-3uzuA:
undetectable
1hxwB-3uzuA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 12 GLY A  46
GLY A  48
GLU A  71
LEU A  76
LEU A 118
None
1.11A 1jg2A-3uzuA:
8.7
1jg2A-3uzuA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 11 GLY A  46
GLY A  48
GLU A  71
LEU A  76
ASP A  94
None
0.65A 1jg3A-3uzuA:
8.7
1jg3A-3uzuA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 11 GLY A  46
GLY A  48
GLU A  71
LEU A  76
LEU A 118
None
1.11A 1jg3A-3uzuA:
8.7
1jg3A-3uzuA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 11 GLY A  46
GLY A  48
GLU A  71
LEU A  76
ASP A  94
None
0.65A 1jg3B-3uzuA:
8.9
1jg3B-3uzuA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 11 GLY A  46
GLY A  48
GLU A  71
LEU A  76
LEU A 118
None
1.12A 1jg3B-3uzuA:
8.9
1jg3B-3uzuA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
4 / 8 GLU A  44
GLY A  46
GLU A  71
LEU A  76
None
0.53A 1jg4A-3uzuA:
8.9
1jg4A-3uzuA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
4 / 8 GLU A  44
GLY A  46
LEU A  76
ASP A  94
None
0.66A 1jg4A-3uzuA:
8.9
1jg4A-3uzuA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 12 LEU A  21
LEU A  52
ARG A  59
ALA A  33
ALA A  32
None
1.06A 1n5xA-3uzuA:
undetectable
1n5xA-3uzuA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 12 LEU A  21
LEU A  52
ARG A  59
ALA A  33
ALA A  32
None
1.06A 1n5xB-3uzuA:
undetectable
1n5xB-3uzuA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 12 ILE A  45
GLY A  46
GLY A  48
ASN A 117
PRO A 119
None
0.90A 1nv8A-3uzuA:
10.7
1nv8A-3uzuA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
3 / 3 GLU A  89
HIS A  91
HIS A  68
None
0.64A 1oe2A-3uzuA:
undetectable
1oe2A-3uzuA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 10 GLY A  25
VAL A  26
LEU A  21
LEU A  52
ALA A  29
None
1.33A 1pbcA-3uzuA:
2.6
1pbcA-3uzuA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAO_A_SAMA245_0
(ERMC'
METHYLTRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
6 / 12 PHE A  20
ASP A  73
LEU A  76
ILE A  45
PRO A 119
ILE A 122
None
1.20A 1qaoA-3uzuA:
22.5
1qaoA-3uzuA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAO_A_SAMA245_0
(ERMC'
METHYLTRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
9 / 12 PHE A  20
GLU A  44
GLY A  46
GLY A  48
ASP A  73
LEU A  76
ASP A  94
ASN A 117
PRO A 119
None
0.76A 1qaoA-3uzuA:
22.5
1qaoA-3uzuA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAO_A_SAMA245_0
(ERMC'
METHYLTRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
9 / 12 PHE A  20
GLU A  44
GLY A  46
GLY A  48
ASP A  73
LEU A  76
ASP A  94
PRO A 119
ILE A 122
None
0.74A 1qaoA-3uzuA:
22.5
1qaoA-3uzuA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 12 ILE A  45
GLY A  48
ALA A  51
ASN A 117
PRO A 119
None
0.93A 1sg9C-3uzuA:
10.8
1sg9C-3uzuA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 12 LEU A 126
ILE A 115
GLY A 116
PRO A 119
LEU A  67
None
1.02A 1vptA-3uzuA:
8.0
1vptA-3uzuA:
22.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
6 / 12 GLY A  48
LEU A  76
ASP A  94
PRO A 119
ILE A 122
SER A 193
None
0.66A 1zq9A-3uzuA:
26.1
1zq9A-3uzuA:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
6 / 12 LEU A  76
ASP A  94
PRO A 119
ILE A 122
MET A 143
SER A 193
None
0.92A 1zq9A-3uzuA:
26.1
1zq9A-3uzuA:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
3 / 3 GLY A  46
GLU A  71
ASN A 117
None
0.16A 1zq9A-3uzuA:
25.7
1zq9A-3uzuA:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
7 / 12 GLY A  46
GLY A  48
ASN A 117
LEU A 118
PRO A 119
ILE A 122
PHE A 185
None
1.13A 1zq9B-3uzuA:
25.5
1zq9B-3uzuA:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
8 / 12 GLY A  46
GLY A  48
LEU A  76
ASP A  94
ASN A 117
PRO A 119
ILE A 122
PHE A 185
None
0.73A 1zq9B-3uzuA:
25.5
1zq9B-3uzuA:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
6 / 12 GLY A 116
ASN A 117
LEU A 118
PRO A 119
ILE A 122
PHE A 185
None
1.37A 1zq9B-3uzuA:
25.5
1zq9B-3uzuA:
30.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_A_SAMA500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 11 GLU A  44
GLU A  71
ASP A  73
ASP A  94
PRO A 119
None
0.80A 2admA-3uzuA:
12.6
2admA-3uzuA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 12 GLY A 116
VAL A  31
GLY A  50
VAL A  26
ILE A  30
None
0.86A 2bpxB-3uzuA:
undetectable
2bpxB-3uzuA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 12 GLY A 116
VAL A  31
GLY A  50
VAL A  26
ILE A  30
None
0.87A 2ienB-3uzuA:
undetectable
2ienB-3uzuA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_B_AZZB1211_1
(DEOXYNUCLEOSIDE
KINASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 12 LEU A 233
PHE A 242
VAL A 240
ARG A 272
ALA A 271
None
0.96A 2jj8B-3uzuA:
undetectable
2jj8B-3uzuA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 12 GLY A  46
GLY A  48
LEU A  52
ASP A  73
ASN A 117
None
0.78A 2nxeB-3uzuA:
12.1
2nxeB-3uzuA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
3 / 3 MET A 228
VAL A 217
GLU A 260
None
0.73A 2x9gA-3uzuA:
4.9
2x9gA-3uzuA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
6 / 12 GLY A  46
GLY A  48
ALA A  51
LEU A  52
ASN A 117
PRO A 119
None
1.10A 2zulA-3uzuA:
10.7
2zulA-3uzuA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 12 GLY A 116
VAL A  31
GLY A  50
VAL A  26
ILE A  30
None
0.78A 3bvbA-3uzuA:
undetectable
3bvbA-3uzuA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 12 GLY A  46
GLY A  48
LEU A  52
ASP A  73
ASN A 117
None
0.82A 3cjtO-3uzuA:
12.2
3cjtO-3uzuA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_2
(HIV-1 PROTEASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 12 GLY A 116
VAL A  31
GLY A  50
VAL A  26
ILE A  30
None
0.86A 3cywB-3uzuA:
undetectable
3cywB-3uzuA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 12 GLY A  46
GLY A  48
ALA A  51
ASP A  94
PRO A 119
None
0.70A 3dmfA-3uzuA:
10.6
3dmfA-3uzuA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
6 / 12 GLY A  46
GLY A  48
ALA A  51
LEU A  52
ASN A 117
PRO A 119
None
1.10A 3dmhA-3uzuA:
10.7
3dmhA-3uzuA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DXY_A_SAMA1_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 11 GLU A  44
GLY A  46
GLU A  71
ASP A  94
ALA A  95
None
0.67A 3dxyA-3uzuA:
9.9
3dxyA-3uzuA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DXY_A_SAMA1_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 11 GLU A  44
GLY A  46
GLY A  48
ASP A  94
ALA A  95
None
0.56A 3dxyA-3uzuA:
9.9
3dxyA-3uzuA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_1
(PROTEASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 9 LEU A  88
GLY A  48
VAL A  56
GLY A 116
ILE A  45
None
1.04A 3ektA-3uzuA:
undetectable
3ektA-3uzuA:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FUU_A_ADNA0_1
(DIMETHYLADENOSINE
TRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
7 / 12 GLY A  46
GLY A  48
GLU A  71
ASP A  73
ASP A  94
ALA A  95
ILE A 122
None
0.64A 3fuuA-3uzuA:
24.8
3fuuA-3uzuA:
37.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FUU_A_ADNA0_1
(DIMETHYLADENOSINE
TRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 12 GLY A  48
ASP A  73
ASP A  94
PRO A 119
ILE A 122
None
0.89A 3fuuA-3uzuA:
24.8
3fuuA-3uzuA:
37.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRV_A_ADNA300_1
(DIMETHYLADENOSINE
TRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
9 / 11 GLY A  46
GLY A  48
GLU A  71
ASP A  73
LEU A  76
ASP A  94
ALA A  95
ASN A 117
ILE A 122
None
0.64A 3grvA-3uzuA:
26.1
3grvA-3uzuA:
29.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRV_A_ADNA300_1
(DIMETHYLADENOSINE
TRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
7 / 11 GLY A  48
ASP A  73
LEU A  76
ASP A  94
ASN A 117
PRO A 119
ILE A 122
None
1.05A 3grvA-3uzuA:
26.1
3grvA-3uzuA:
29.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
9 / 12 GLU A  44
GLY A  46
GLY A  48
GLU A  71
ASP A  73
LEU A  76
ASP A  94
ALA A  95
ASN A 117
None
0.65A 3gryA-3uzuA:
26.2
3gryA-3uzuA:
29.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
6 / 12 GLY A  48
ASP A  73
LEU A  76
ASP A  94
ASN A 117
PRO A 119
None
1.15A 3gryA-3uzuA:
26.2
3gryA-3uzuA:
29.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
9 / 12 LEU A  21
GLU A  44
GLY A  46
GLY A  48
GLU A  71
ASP A  73
LEU A  76
ASP A  94
ALA A  95
None
0.57A 3gryA-3uzuA:
26.2
3gryA-3uzuA:
29.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
6 / 12 LEU A  21
GLY A  48
ASP A  73
LEU A  76
ASP A  94
PRO A 119
None
1.04A 3gryA-3uzuA:
26.2
3gryA-3uzuA:
29.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
7 / 12 LEU A  52
GLY A  48
GLU A  71
ASP A  73
LEU A  76
ASP A  94
ALA A  95
None
1.22A 3gryA-3uzuA:
26.2
3gryA-3uzuA:
29.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 11 GLY A  46
THR A  53
GLU A  71
ASP A  94
ALA A  95
None
1.31A 3id5B-3uzuA:
11.9
3id5B-3uzuA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_F_SAMF301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 11 GLY A  46
THR A  53
GLU A  71
ASP A  94
ALA A  95
None
1.30A 3id5F-3uzuA:
10.5
3id5F-3uzuA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 12 GLY A 116
VAL A  31
GLY A  50
VAL A  26
ILE A  30
None
0.74A 3jvyA-3uzuA:
undetectable
3jvyA-3uzuA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_2
(PROTEASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 11 LEU A  88
GLY A  48
VAL A  56
GLY A 116
ILE A  45
None
0.82A 3nu3B-3uzuA:
undetectable
3nu3B-3uzuA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_2
(PROTEASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 9 LEU A  88
GLY A  48
VAL A  56
GLY A 116
ILE A  45
None
0.87A 3nujB-3uzuA:
undetectable
3nujB-3uzuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_2
(PROTEASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 9 LEU A  88
GLY A  48
VAL A  56
GLY A 116
ILE A  45
None
0.87A 3nuoB-3uzuA:
undetectable
3nuoB-3uzuA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_2
(HIV-1 PROTEASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 10 LEU A  88
GLY A  48
VAL A  56
GLY A 116
ILE A  45
None
0.96A 3oy4B-3uzuA:
undetectable
3oy4B-3uzuA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
4 / 4 GLY A  48
GLY A  50
THR A  53
LEU A  88
None
0.92A 3si7C-3uzuA:
undetectable
3si7D-3uzuA:
undetectable
3si7C-3uzuA:
22.64
3si7D-3uzuA:
22.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
3 / 3 GLU A  71
ASP A  73
ASP A  94
None
0.48A 4gc9A-3uzuA:
25.2
4gc9A-3uzuA:
30.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_A_SAMA900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
6 / 12 GLY A  46
GLY A  48
LEU A  72
ASP A  94
ALA A  95
ILE A 122
None
0.93A 4krhA-3uzuA:
11.5
4krhA-3uzuA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 12 GLY A  46
GLY A  48
LEU A  72
ALA A  95
ILE A 122
None
0.92A 4krhB-3uzuA:
11.3
4krhB-3uzuA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_2
(HIV-1 PROTEASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 9 LEU A  88
GLY A  48
VAL A  56
GLY A 116
ILE A  45
None
0.80A 4rvjB-3uzuA:
undetectable
4rvjB-3uzuA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_2
(HIV-1 PROTEASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 9 LEU A  88
GLY A  48
VAL A  56
GLY A 116
ILE A  45
None
0.81A 4rvjD-3uzuA:
undetectable
4rvjD-3uzuA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
4 / 7 SER A 132
ASP A 210
GLY A 215
GLU A 216
None
0.94A 5btfA-3uzuA:
undetectable
5btfB-3uzuA:
2.1
5btfC-3uzuA:
undetectable
5btfA-3uzuA:
21.63
5btfB-3uzuA:
23.00
5btfC-3uzuA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
4 / 7 GLY A  46
GLY A  48
GLU A  71
ASP A  94
None
0.48A 5ergB-3uzuA:
11.7
5ergB-3uzuA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_D_SAMD301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 12 ASP A  94
ALA A  95
PRO A 119
GLY A  48
GLU A  71
None
0.93A 5hfjD-3uzuA:
3.9
5hfjD-3uzuA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_A_ADNA401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
4 / 7 GLY A  46
GLU A  71
ASP A  94
ASN A 117
None
0.85A 5mvsA-3uzuA:
10.5
5mvsA-3uzuA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_B_ADNB401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
4 / 8 GLY A  46
GLU A  71
ASP A  94
ASN A 117
None
0.81A 5mvsB-3uzuA:
10.2
5mvsB-3uzuA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_2
(CYTOCHROME P450 2C9)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
3 / 3 LEU A 214
VAL A 258
ASP A 259
None
0.62A 5x23A-3uzuA:
undetectable
5x23A-3uzuA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 11 GLY A  46
GLU A  71
ASP A  94
ALA A  95
LEU A 126
None
1.07A 5x6yA-3uzuA:
4.4
5x6yA-3uzuA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 10 GLY A  46
GLU A  71
ASP A  94
ALA A  95
LEU A 126
None
1.00A 5x6yB-3uzuA:
4.5
5x6yB-3uzuA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 11 GLY A  46
GLU A  71
ASP A  94
ALA A  95
LEU A 126
None
0.97A 5x6yC-3uzuA:
4.4
5x6yC-3uzuA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_0
(HIV-1 PROTEASE)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
5 / 12 GLY A 116
VAL A  31
GLY A  50
VAL A  26
ILE A  30
None
0.78A 6dj1A-3uzuA:
undetectable
6dj1A-3uzuA:
13.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IFT_A_SAMA301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)
3uzu RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Burkholderia
pseudomallei)
9 / 12 PHE A  20
LEU A  21
GLU A  44
ILE A  45
GLY A  46
GLY A  48
ALA A  51
ASP A  73
LEU A  76
None
0.64A 6iftA-3uzuA:
26.0
6iftA-3uzuA:
30.84