SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v0i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_H_AG2H7012_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3v0i VOLTAGE-SENSOR
CONTAINING
PHOSPHATASE
(Ciona
intestinalis) 		4 / 6 ARG A 398
LEU A 262
ASP A 263
GLY A 365
 None
 0.95A 1n13H-3v0iA:
undetectable
1n13K-3v0iA:
undetectable		 1n13H-3v0iA:
15.60
1n13K-3v0iA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3v0i VOLTAGE-SENSOR
CONTAINING
PHOSPHATASE
(Ciona
intestinalis) 		5 / 12 PHE A 570
LEU A 568
VAL A 566
PHE A 511
ALA A 413
 None
 1.15A 1q23A-3v0iA:
undetectable
1q23B-3v0iA:
undetectable		 1q23A-3v0iA:
20.62
1q23B-3v0iA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0F_A_STRA1499_1
(CYTOCHROME P450 3A4)		 3v0i VOLTAGE-SENSOR
CONTAINING
PHOSPHATASE
(Ciona
intestinalis) 		4 / 4 PHE A 527
ASP A 549
PHE A 529
VAL A 566
 None
 1.23A 1w0fA-3v0iA:
undetectable		 1w0fA-3v0iA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3v0i VOLTAGE-SENSOR
CONTAINING
PHOSPHATASE
(Ciona
intestinalis) 		3 / 3 LYS A 553
ASP A 331
CYH A 363
 None
None
SO4  A 601 ( 4.4A)
 1.25A 2br4F-3v0iA:
undetectable		 2br4F-3v0iA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3v0i VOLTAGE-SENSOR
CONTAINING
PHOSPHATASE
(Ciona
intestinalis) 		4 / 8 PRO A 551
ASN A 550
VAL A 452
GLY A 453
 None
 0.92A 3em0B-3v0iA:
undetectable		 3em0B-3v0iA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 3v0i VOLTAGE-SENSOR
CONTAINING
PHOSPHATASE
(Ciona
intestinalis) 		3 / 3 THR A 565
LYS A 437
GLU A 547
 None
 0.80A 3ijdB-3v0iA:
undetectable		 3ijdB-3v0iA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 3v0i VOLTAGE-SENSOR
CONTAINING
PHOSPHATASE
(Ciona
intestinalis) 		4 / 5 VAL A 509
LEU A 568
VAL A 541
PHE A 529
 None
 0.98A 4lb0B-3v0iA:
undetectable		 4lb0B-3v0iA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3v0i VOLTAGE-SENSOR
CONTAINING
PHOSPHATASE
(Ciona
intestinalis) 		3 / 3 ASP A 487
ASN A 456
PHE A 476
 None
 0.77A 5dsgB-3v0iA:
undetectable		 5dsgB-3v0iA:
19.86